Traditional Chinese medicinal composition for treating fever in children as well as preparation method and application thereof

A technology of children's fever and composition, which is applied in the direction of drug combination, antipyretics, and pharmaceutical formulas, can solve the problems of toxic side effects, cell damage, etc., and achieve the effect of rapid development, visceral energy, clear spirit, and vigorous vitality

Inactive Publication Date: 2013-07-10
鞠建明
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

High heat can cause dehydration, convulsions, and cell destruction. If chemical drugs are used, they will have relatively large toxic and

Method used

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  • Traditional Chinese medicinal composition for treating fever in children as well as preparation method and application thereof
  • Traditional Chinese medicinal composition for treating fever in children as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
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Example Embodiment

[0024] Example 1: Combine 6g of Astragalus vulgaris, 8g of Viola serrata, 6g of mallow seeds, 7g of gypsum, 6g of nepeta, 12g of glutinous root, 6g of forsythia, 12g of pueraria lobata, 6g of scutellaria, 12g of scrophulariaceae, 6g of wild rehmannia, and 12g of parsnip , Add water to decocting twice, the first time adding water is 10 times the weight of the medicinal material, decocting for 1.5h, the second time adding water is 8 times the weight of the medicinal material, decocting for 1.5h, combined decoction, 0.07MPa, 60- Concentrate under reduced pressure at 70°C to 65°C for the extract with a relative density of 1.15, add 95% (v / v) ethanol to make the alcohol content 75% (v / v), stir, stand for 24 hours, filter, and filtrate Concentrate under reduced pressure at 0.07MPa and 65°C to a relative density of 1.25 at 65°C, and recover ethanol to obtain a concentrate, which is spray-dried (conditions: inlet air temperature is 100°C, outlet air temperature is 85°C , The material t...

Example Embodiment

[0025] Example 2: Combine 9g of Astragalus vulgaris, 6g of Viola serrata, 9g of mallow seeds, 5g of gypsum, 9g of nepeta, 9g of glutinous root, 9g of forsythia, 9g of pueraria lobata, 9g of scutellaria, 9g of scrophulariaceae, 9g of scutellaria, and 9g of fangfeng , Add water to decocting twice, the first time adding water is 8 times the weight of the medicinal material, decocting for 1h, the second time adding water is 6 times the weight of the medicinal material, decocting for 1h, combined decoction, 0.07MPa, 60-70℃ The relative density is 1.20 when concentrated under reduced pressure to 65℃, add 95% (v / v) ethanol to make the alcohol content reach 80% (v / v), stir, stand for 24 hours, filter, the filtrate is at 0.07MPa, 65 Concentrate under reduced pressure at ℃ to 65℃ to a relative density of 1.30, and recover ethanol to obtain a concentrated solution, filter, add water and sucrose to prepare an oral solution.

Example Embodiment

[0026] Example 3: Combine 12g of 薢薢, 4g of Viola serrata, 12g of mallow seeds, 3g of gypsum, 12g of nepeta, 6g of rhizome, 12g of forsythia, 6g of Pueraria lobata, 12g of scutellaria, 6g of Scrophulariaceae, 12g of Radix Scrophulariaceae, and 6g of Parsnips , Add water to decoct twice, the first time adding water is 12 times the weight of the medicinal material, decocting for 2h, the second time adding water is 10 times the weight of the medicinal material, decocting for 2h, combined decoction, 0.07MPa, 60-70℃ Concentrate under reduced pressure to an extract with a relative density of 1.20 at 65°C, add 95% (v / v) ethanol to make the alcohol content reach 85% (v / v), stir, stand for 24 hours, filter, and the filtrate at 0.07 MPa, 65°C under reduced pressure and concentration to 65°C, the relative density is 1.30, and ethanol is recovered to obtain the concentrated solution, which is spray-dried (conditions: inlet air temperature is 120°C, outlet air temperature is 90°C, material T...

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Abstract

The invention provides a traditional Chinese medicinal composition for treating fever in children. The composition is characterized by being prepared from the following raw materials in parts by weight: 6 to 12 parts of yam rhizome, 4 to 8 parts of Chinese violet, 6 to 12 parts of chingma abutilon seed, 3 to 7 parts of gyp, 6 to 12 parts of schizonepeta, 6 to 12 parts of cyrtomium rhizome, 6 to 12 parts of fructus forsythiae, 6 to 12 parts of kudzuvine root, 6 to 12 parts of baical skullcap root, 6 to 12 parts of radix scrophulariae, 6 to 12 parts of raw rehmannia root, and 6 to 12 parts of divaricate saposhnikovia root. By adopting a corresponding preparation method, oral solution, tablets, capsules or granules can be prepared. The traditional Chinese medicinal composition has the functions of dispelling wind and clearing heat, nourishing yin and removing toxicity, and can be used for treating fever in children.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating fever in children, a preparation method and application thereof. Background technique [0002] Children in the growth and development stage often have immature nervous systems and are easily disturbed by factors such as climate, environment, improper feeding, diseases, and drugs. This is the fundamental reason why children are prone to fever in summer. Fever, the first "protective wall" in the body Fever is a symptom and a normal immune response in the body, which can help kill bacteria and improve resistance. When fever occurs, various immune functions in the body are "activated", metabolism increases, antibody synthesis increases and phagocyte activity increases. High heat can cause dehydration, convulsions, and cell destruction. If chemical drugs are used, they will have relatively large toxic and s...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P29/00A61K33/06
Inventor 鞠建明刘克冕
Owner 鞠建明
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