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Fluid connector devices and methods of making and using the same

A technology of connectors and connector components, applied in chemical instruments and methods, supporting appliances, laboratory appliances, etc., can solve problems such as increasing pressure and restricting the applicability of microfluidic devices

Inactive Publication Date: 2013-07-10
GENERAL ELECTRIC CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Furthermore, open pipetting techniques do not allow the use of elevated pressures for fluid delivery, such as delivery by pumps, thereby further limiting the applicability of microfluidic devices.

Method used

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  • Fluid connector devices and methods of making and using the same
  • Fluid connector devices and methods of making and using the same
  • Fluid connector devices and methods of making and using the same

Examples

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Embodiment Construction

[0023] The present invention relates to microfluidic interconnect devices for introducing or extracting fluids (liquid or gas) into or from microfabricated fluidic devices, such as microfluidic devices. In certain embodiments, the fluidic connector device functions as a microfluidic interconnection device to introduce or extract fluids from the microfluidic device. Fluidic connector devices can be used to interface microfluidic devices with each other or with other fluidic components and systems such as, but not limited to, pumps, filters, syringes, aerosol collectors, flow cytometers, and chemical analyzers. In one embodiment, a fluidic connector arrangement can couple at least one fluidic conduit to a corresponding port of the microfluidic device.

[0024] In certain embodiments, the fluidic connector devices can be used for synthetic or analytical operations. As described in detail below, the present technology offers several advantages for use in chemical analysis or synt...

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PUM

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Abstract

A fluid connector device (10) is provided. The fluid connector device includes a coupling substrate (12) having a conformal recess (20), a reconnectable fitting (18) disposed in the recess to provide a first passageway, and a force applying element (16) operatively coupled to the reconnectable fitting (18), or the coupling substrate (12), or both the reconnectable fitting (18) and the coupling substrate (12) to at least partially provide a sealing force between the reconnectable fitting (18) and the coupling substrate (12), wherein at least one of the force applying element (16), the reconnectable fitting (18), and the coupling substrate (12) comprises one or more degrees of freedom for self alignment of the reconnectable fitting (18) and the conformal recess (12).

Description

technical field [0001] Embodiments of the present invention relate to microfluidic devices, such as microfluidic devices, and more particularly, to fluidic connectors for introducing fluids into microfluidic devices. Background technique [0002] Typically, microfluidic devices employ a network of chambers connected by microchannels. Microchannels and chambers can have mesoscale to microscale dimensions. Microfluidic devices offer various advantages when used in analytical applications, including the ability to use small sample sizes. For example, sample sizes for microfluidic devices may be on the nano-liter scale. [0003] Advantageously, microfluidic devices can be produced at relatively low cost and can perform many specific operations, including mixing, dispensing, reacting, and detecting. However, introducing fluid samples and reagents into microfluidic devices is a challenge, especially when multiple inputs are required. For example, in a lab-on-a-chip setup, a mi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00
CPCB01L3/502715B01J19/0093B01J2219/00806B01J2219/00813B01L9/527B01L2200/027B01L2200/0689B01L2300/0861B01L2300/123B01L2300/161
Inventor M.巴勒C.任施V.桑珀
Owner GENERAL ELECTRIC CO
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