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A method for test of human exhaled breath by using laser spectrums of optical frequency combs

A spectral detection, exhaled breath technology, applied in the direction of color/spectral characteristic measurement, etc., can solve the problem of immature technology, and achieve the effect of excellent sensitivity and specificity, accurate measurement, fast and short measurement time

Inactive Publication Date: 2013-09-11
UNIV OF SHANGHAI FOR SCI & TECH
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Problems solved by technology

At present, the method of using optical comb laser spectrum to detect human exhaled breath has not been reported so far, and no related mature technology has appeared

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  • A method for test of human exhaled breath by using laser spectrums of optical frequency combs

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Embodiment Construction

[0023] The present invention is described in detail below in conjunction with accompanying drawing and embodiment, but present embodiment can not be used for limiting the present invention, and every similar method and similar variation thereof that adopt the present invention all should be included in the protection scope of the present invention.

[0024] The optical comb laser spectrum detector consists of two parts: software and hardware, and the hardware part includes a computer, an optical comb generator, an inhalation tube, an exhalation tube, a gas sample chamber, a filter, a temperature sensor, an air pressure sensor, a photodetector and a spectrum analysis Module; the software part includes system control software, Fourier spectrum and spectrum restoration algorithm, and a standard database of gases contained in human exhaled breath.

[0025] One end of the inhalation tube is connected to the filter, and the filter is connected to the human mouth. The exhalation tube ...

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Abstract

A method for test of human exhaled breath by using laser spectrums of optical frequency combs is characterized by: employing two groups of optical frequency combs with different pulse repetition frequencies to beat each other so that frequency spectrum signals are reduced to a microwave frequency range; employing a simple conventional microwave detection method to obtain frequency spectrum absorption and phase information of the exhaled breath in the entire optical frequencies, thereby to obtain gas components and traces; and determining a patient's possible condition by the analysis of components and corresponding absorption coefficients of each gas spectrum curve. The method for test of human exhaled breath by using laser spectrums of optical frequency combs of the invention can quickly measure the spectrum of human exhaled breath in a wide range once and for all, achieving a short measurement time and accurate measurement to real-time changing samples. The method has advantages of being non-invasive, quantitative, safe, simple, convenient, quick, repeatable, etc., with sensitivity and specificity better than conventional bronchoscopy.

Description

technical field [0001] The invention relates to a method for detecting exhaled air of a human body by using an optical comb laser spectrum. It belongs to the technical field of laser spectrum utilization. Background technique [0002] From 2006 to 2010, the annual average concentration of PM2.5 in Beijing, Shanghai, Guangzhou, Xi'an and Shenyang increased from 55 μg / m 3 to 182μg / m 3 It is the annual average guidance value of the World Health Organization (WHO) "Global Air Quality Guidelines" (10μg / m 3 ) is 5 to 18 times that of the U.S. Environmental Protection Agency (EPA) PM2.5 annual average standard value (15μg / m 3 ) 4 to 12 times. Since January 12, 2013, the real-time concentration of PM2.5 at monitoring points such as Beijing South Third Ring Road and Olympic Sports Center has exceeded 900μg / m 3 , the monitoring value of Xizhimen pollution monitoring point can reach as high as 993μg / m 3 . Therefore, the recent increase in PM2.5 has led to a rapid increase in out...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/31
Inventor 郝强谷付兴陈杰曾和平
Owner UNIV OF SHANGHAI FOR SCI & TECH
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