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Montmorillonite product and application thereof

A technology of montmorillonite and montmorillonite powder, applied in the application, food preparation, aluminum/calcium/magnesium active ingredients and other directions, can solve the problems of incomplete defecation, reduced defecation frequency, poor defecation, etc., to improve defecation quality, Improve smoothness and ease of use

Inactive Publication Date: 2013-10-09
赫康贸易(上海)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Commercialized drugs include Smecta, etc., but the main side effects are constipation such as reduced frequency of defecation, poor defecation, and incomplete defecation

Method used

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  • Montmorillonite product and application thereof
  • Montmorillonite product and application thereof
  • Montmorillonite product and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The preparation of embodiment 1 montmorillonite suspension

[0031] Take pharmaceutical grade montmorillonite powder (can be purchased from Inner Mongolia Runlong Chemical Co., Ltd., in line with the national standard WS1-(X-165)-2004Z), collect the powder through a 40-mesh sieve, add purified water to prepare a suspension of 8 mg / ml liquid, sealed and then boiled and sterilized for 30 minutes to obtain the montmorillonite suspension.

[0032] Before use, the suspension is shaken and mixed, and it is taken orally. Its mouthfeel is close to the taste of tap water in areas with hard water in northern my country (such as Inner Mongolia, Hebei, etc.), which is acceptable for adults.

Embodiment 2

[0033] The preparation of embodiment 2 montmorillonite suspension preparations

[0034] Take pharmaceutical grade montmorillonite powder, collect the powder through a 40-mesh sieve, sub-package after cobalt 60 sterilization, 4g per bag; get 500ml of apple juice drink (commercially available, (pure) fruit juice content 10%) in addition. These two constitute the montmorillonite suspension formulation.

[0035] Before use, mix the pharmaceutical-grade montmorillonite powder into apple juice drink and take it orally in the form of suspension. The taste is good, and the unpleasant taste of montmorillonite is completely covered.

Embodiment 3

[0036] The curative effect of embodiment 3 montmorillonite suspensions

[0037] In the case of informed consent, 408 volunteers (22-65 years old) participated in the experiment, including the following categories:

[0038] Class 1: 17 person-times, those with severe constipation symptoms, that is, the number of defecation within 14 days before the test is 6 times or less, and the feces are dry and lumpy, and the montmorillonite suspension prepared in Example 1 is replaced when drinking water every day Taking 500ml or 1500ml for 5 consecutive days, except for 1 person, the rest did not show improvement in constipation, and 5 of them said that constipation was aggravated, so this kind of test was terminated.

[0039] The 2nd class: 6 person-times, those who have diarrhea symptoms, replace 500ml of montmorillonite suspension prepared by taking embodiment 1 when drinking water every day, take 3 days continuously, have 1 people's diarrhea situation as before, 2 people's diarrhea si...

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PUM

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Abstract

The invention provides a low-concentration montmorillonite product and an application thereof in preparing medicines, foodstuff or health products. The product facilitates thorough defecation, and is used for improving a smooth degree of the defecation, treating or preventing mild and moderate constipation, and / or improving visual senses of the defecation, and thus is good for the defecation.

Description

field of invention [0001] The invention belongs to the field of medicine / food / health care products, in particular, the invention relates to medicine / food / health care products and application thereof which are beneficial to the thorough defecation of non-severe constipation and non-diarrhea people. Background of the invention [0002] Montmorillonite is recognized as having the effect of astringent intestines and antidiarrheal, and is used to treat diarrhea and gastroenteritis caused by long-term diarrhea (see Chinese patents 98126152, 00109389, 200410042539, 200610005685, 200610037180, 200610050245, 200610050246, 205074002, etc.) . Commercialized drugs include Smecta, etc., but the main side effects are constipation such as reduced frequency of defecation, poor defecation, and incomplete defecation. [0003] Moreover, in the prior art, montmorillonite is basically formulated into oral solid preparations (such as tablets, capsules, and even enteric drug type) and administere...

Claims

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Application Information

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IPC IPC(8): A61K33/06A23L1/29A23L2/02A23L2/38A61P1/10A23L33/00
Inventor 陈建勳林咏琪
Owner 赫康贸易(上海)有限公司
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