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Therapeutic agent for meniere

A therapeutic agent and dose technology, applied in the field of Meniere’s therapeutic agent, can solve the problems of large surgical trauma, insignificant improvement of symptoms, and easy recurrence of patients’ symptoms, so as to improve the microcirculation of the inner ear, reduce the stenosis and occlusion of the inner ear blood vessels, relieve The effect of stray water

Active Publication Date: 2015-04-22
童绥君
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0020] At present, the treatment methods for Meniere's disease are mostly one-sided. Medications that mainly regulate autonomic nerve function, improve inner ear microcirculation, and relieve labyrinth hydrops are not effective. Surgical treatment is traumatic and can improve symptoms more than internal medicine. There is no advantage to treatment
Through the research of multiple groups of clinical medical records, it is found that the currently used clinical methods for the treatment of Meniere's disease have short curative effects on patients with dizziness, hearing loss, tinnitus, and stuffy ears, and the symptoms are not significantly improved, and the symptoms of patients are easy to repeat

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042]Outpatient Chen XX, female, 64 years old, came to our hospital with "repeated dizziness and hearing loss in the right ear for more than 2 years". History of present illness: dizziness due to no obvious inducement more than 2 years ago, manifested as visual rotation, not related to body position change, accompanied by nausea and vomiting in severe cases, lasting from 1 hour to several hours each time, accompanied by hearing progress in the right ear Sexual decline, the sound of listening to mobile phones in the right ear is significantly worse than that in the left ear, occasionally tinnitus, no hoarseness, difficulty swallowing, no abnormal mental behavior, no weakness and numbness of limbs, no fever, chills, and multiple visits to other hospitals for symptomatic treatment (specific Unknown) Symptoms did not improve, so he was referred to our hospital. Physical examination: T36.3°C, P77 beats / min, R19 beats / min, BP122 / 80mmHg, clear mind, normal spirit, clear speech, corr...

Embodiment 2

[0044] Outpatient Zhu XX, female, 58 years old, came to our hospital with "repeated dizziness and hearing loss in both ears for more than 3 years". History of present illness: due to dizziness without obvious inducement more than 3 years ago, manifested as spinning vision, a sense of spinning world, not related to body position changes, accompanied by nausea and vomiting, lasting about 1 hour each time, accompanied by progressive hearing loss in both ears, No abnormal mental behavior, no hoarseness, difficulty swallowing, no limb weakness and numbness, no fever, chills, and repeated visits to other hospitals for symptomatic treatment (specifically unknown). The symptoms did not improve, so he was referred to our hospital. Physical examination: T36.6°C, P79 beats / min, R19 beats / min, BP113 / 69mmHg, clear mind, normal spirit, clear speech, correct answer, good response, good memory and comprehension, double pupils are equal in size, About 2.5mm in diameter, sensitive to light refl...

Embodiment 3

[0046] Outpatient Zhuang XX, male, 50 years old, came to our hospital with "repeated dizziness and tinnitus for more than 1 year". History of present illness: dizziness due to no obvious incentives more than 1 year ago, manifested as spinning vision, a sense of spinning, not related to body position changes, accompanied by nausea and vomiting in severe cases, lasting 1-2 hours each time, accompanied by tinnitus, as paroxysmal Hairy hair-like murmurs, no limb weakness and numbness, no hoarseness, difficulty swallowing, no fever, chills, palpitations, chest tightness, and dyspnea. She visited other hospitals for symptomatic treatment (specifically unknown) and the symptoms did not improve. Consult our hospital. Physical examination: T36.3°C, P88 beats / min, R19 beats / min, BP119 / 78mmHg, clear mind, normal spirit, clear speech, correct answer, good response, good memory and comprehension, double pupils are equal in size, About 2.5mm in diameter, sensitive to light reflection, free...

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Abstract

The invention discloses a therapeutic agent for meniere. The therapeutic agent is mainly prepared from the following ingredients: deanxit, amitriptyline, clonazepam, bayaspirin and perenan. The target spot of the therapeutic agent acts on a plurality of etiological factors of the meniere, so that the therapeutic agent has obvious effects on adjustment of central neurotransmitter, adjustment of autonomic nervous function, improvement of inner ear microcirculation, alleviation of hydrolabyrinth, alleviation of inner ear vascular stricture or occlusion and the like, obviously improves the symptoms such as dizziness, deafness and tinnitus of patients and has no obvious drug side effects.

Description

technical field [0001] The present invention relates to a Meniere therapeutic agent. Background technique [0002] Meniere's disease is considered an idiopathic membranous hydrops. In 1938, Hallpike and Cairns reported that the main pathological change of this disease was membrane labyrinthine hydrops. [0003] The cause of Meniere's disease [0004] (1) Central neurotransmitter disorder: Many patients have mood swings, mental tension, anxiety, and depression before the onset of the disease. The disorder of central transmitter regulation makes the internal environment of central transmitter unstable, especially affects the vertigo center, thereby causing symptoms such as vertigo and vagal excitation, which may be the basic background of Meniere's disease. [0005] (2) Autonomic nervous dysfunction: Due to the dysfunction of the autonomic nervous system, the sympathetic nerve excitability increases, and the small blood vessels of the inner ear spasm, resulting in labyrinth...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/616A61K31/496A61K31/135A61K31/5513A61K31/48A61P1/08A61P27/16A61P25/00
Inventor 童绥君马琪林毕敏李剑鹏江斌
Owner 童绥君
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