Preparation method of gluconic acid and glucaric acid

A technology of glucaric acid and gluconic acid, which is applied in the field of organic electrochemical synthesis, can solve the problems of product aldehyde and acid yield, regulation, and hindering new reactions, etc., so as to maintain continuous high efficiency, simple and stable process excellent effect

Inactive Publication Date: 2013-12-11
TIANJIN POLYTECHNIC UNIV
View PDF5 Cites 25 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Even so, there are still some shortcomings in organic electrochemical synthesis: (1) Electrochemical synthesis cannot separate reactants and products in time after the reaction, which will lead to further oxidation of products and other side reactions, which will eventually affect the reaction. Selectivity and yield of the target product; (2) The reactant can only rely on the electric field to transfer from the solution body to the electrode surface, and then the...

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of gluconic acid and glucaric acid
  • Preparation method of gluconic acid and glucaric acid
  • Preparation method of gluconic acid and glucaric acid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Nano TiO 2 The supported titanium-based electrocatalytic membrane is used as the anode, and the auxiliary electrode stainless steel is used as the cathode, which are respectively connected to a stabilized power supply via wires to form an electrocatalytic membrane reactor device. Prepare 50.5mmol / L glucose solution and place it in the membrane reactor at 0.1mmol / LH 2 SO 4 The solution is used as an electrolyte at room temperature and pressure, working voltage 2.8V, current density 3mA / cm 2 And membrane flux is 3.0L / m 2 ·Under the condition of h, the electrocatalytic membrane is used to catalyze the oxidation of glucose to prepare gluconic acid and glucaric acid. At the same time, the peristaltic pump is used to absorb the membrane permeate, and the target product obtained is separated from the reaction liquid in real time through the membrane osmosis. , The membrane permeate is separated and purified to obtain gluconic acid and glucaric acid products. The components of th...

Embodiment 2

[0042] Nano MnO 2 The supported titanium-based electrocatalytic membrane is used as the anode, and the auxiliary electrode stainless steel is used as the cathode to form an electrocatalytic membrane reactor device. Prepare 75.25mmol·L -1 The glucose solution is placed in the membrane reactor, with 0.1mmol / LNa 2 SO 4 The solution is used as the electrolyte, and the aqueous solution containing glucose and electrolyte is placed in the electrocatalytic membrane reactor at room temperature and pressure, working voltage 3.1V, current density 4mA / cm 2 And membrane flux is 2.0L / m 2 ·Under the condition of h, the electrocatalytic membrane is used to catalyze the oxidation of glucose to prepare gluconic acid and glucaric acid. At the same time, the peristaltic pump is used to absorb the membrane permeate, and the target product obtained is separated from the reaction liquid in real time through the membrane osmosis. , The membrane permeate is separated and purified to obtain gluconic acid ...

Embodiment 3

[0044] Nano WO 3 The supported titanium-based electrocatalytic membrane is used as the anode, and the auxiliary electrode stainless steel is used as the cathode to form an electrocatalytic membrane reactor device. Prepare 101mmol·L -1 The glucose solution is placed in a membrane reactor, with 0.1mmol / L NaCl solution as electrolyte, at room temperature and pressure, working voltage 3.5V, current density 6mA / cm 2 And membrane flux is 1L / m 2 ·Under the condition of h, the electrocatalytic membrane is used to catalyze the oxidation of glucose to prepare gluconic acid and glucaric acid. At the same time, the peristaltic pump is used to absorb the membrane permeate, and the target product obtained is separated from the reaction liquid in real time through the membrane osmosis. , The membrane permeate is separated and purified to obtain gluconic acid and glucaric acid products. The components of the permeate sample were analyzed by high performance liquid chromatography. Calculating u...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a preparation method of gluconic acid and glucaric acid in the technical field of organic electrochemistry synthesis. The preparation method comprises the steps that an electro-catalytic membrane serving as an anode and an auxiliary electrode serving as a cathode are connected with a voltage-stabilized source by wires to form an electro-catalytic membrane reactor; by taking a glucose aqueous solution as a reactant, and an inorganic substance as an electrolyte, gluconic acid and glucaric acid are prepared by catalytic oxidation of glucose with the electro-catalytic membrane under the action of an electric field; membrane penetration liquid is collected by suction of a peristaltic pump; obtained target products are separated from reaction liquid in real time by permeation of the membrane; the membrane penetration liquid is separated and purified to form gluconic acid and glucaric acid products; and yields of gluconic acid and glucaric acid are adjusted and controlled by adjusting and controlling current density and membrane flux. The preparation method integrates catalytic oxidation and separation functions, and can separate the obtained target products from the reaction liquid timely, so that the continuous high efficiency of the electro-catalytic membrane is maintained effectively; a side reaction is avoided; and the selectivity of the target products is improved.

Description

Technical field [0001] The invention belongs to the technical field of organic electrochemical synthesis, and particularly relates to a method for preparing gluconic acid and glucaric acid. Background technique [0002] D-gluconic acid (D-gluconic acid) is an important intermediate for products in the chemical, food, pharmaceutical, light industry and other industries, and has a very broad application prospect. The current world output of gluconic acid exceeds 100,000 tons per year. As a high value-added organic acid, gluconic acid is usually produced by oxidation of glucose, the most abundant monosaccharide in nature. Among them, the fermentation oxidation method is the main route for the industrial preparation of gluconic acid and the reaction equation is as follows: [0003] [0004] The method uses biological enzymes to oxidize glucose to prepare gluconic acid, without adding other oxidants that are harmful to the environment, and the production cost is low. However, this me...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C25B3/02C25B3/23
Inventor 李建新王虹宾德善
Owner TIANJIN POLYTECHNIC UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap