Preparation method of film coating for Salvia miltiorrhiza tablet

A technology of film coating and Danshen tablets, which is applied in the field of film coating preparation of Danshen tablets, to achieve the effects of increasing dissolution rate, improving clinical efficacy and reducing costs

Inactive Publication Date: 2014-01-22
LUOYANG SHUNSHI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But so far, there is no film-coated product of Danshen tablets on the market.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Take 1.6kg of film coating material and put it in the slurry mixing tank, add 15kg of 95% ethanol, stir evenly, put 100kg of pre-pressed Danshen tablet cores in the coating machine, turn on the hot air, and turn the main machine to make the tablets in the coating machine. Roll in the washing machine, the temperature gradually rises to 41.5°C, adjust the spray gun, spray the uniformly stirred coating material solution on the rolling Danshen tablet core, stop spraying when the color is uniform, and dry it to obtain Danshen tablet film-coated tablet product.

Embodiment 2

[0031] Take 1.6kg of film coating material and put it in the slurry mixing tank, add 19kg of absolute ethanol, stir evenly, put 100kg of pre-pressed Danshen tablet cores in the coating machine, turn on the hot air, and turn the main machine to make the tablets in the coating machine. Roll in the washing machine, the temperature gradually rises to 40°C, adjust the spray gun, and spray the evenly stirred coating material solution on the rolling Danshen tablet core. When the color is uniform, stop spraying and dry it. Danshen tablet film-coated tablet product was obtained.

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PUM

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Abstract

The invention relates to a preparation method of a film coating for a Salvia miltiorrhiza tablet. The preparation method of the film coating for the Salvia miltiorrhiza tablet comprises the following steps: 1, slurry preparation: dissolving 49% of a high-molecular polymer, 12% of an antitackiness agent, 5% of an adhesive, 20% of a plasticizer, 4% of a coloring agent and 10% of a photophobic agent in ethanol; 2, preheating: placing a pre-pressed Salvia miltiorrhiza tablet core in a coating machine, and rising the temperature to 39-40DEG C; 3, spraying: uniformly spraying the Salvia miltiorrhiza tablet core with the above obtained ethanol solution of a coating material, stopping spraying when the obtained color is uniform, and drying to obtain the film coating for the Salvia miltiorrhiza tablet core. The preparation method of the film coating for the Salvia miltiorrhiza tablet core has the protruding advantages of reduced production cost, substantially shortened production time, good moisture resistance and the like.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a preparation method for film coating of Danshen tablets. Background technique [0002] Danshen tablet is a traditional Chinese medicine that can promote blood circulation and remove blood stasis. It is mainly used for thoracic obstruction caused by blood stasis. Symptoms include chest pain, fixed pain spot, dark purple tongue; coronary heart disease and angina pectoris, see the above syndromes, etc. [0003] Film coating refers to wrapping a relatively stable coating film outside the tablet core. The function of tablet coating film coating is to protect the tablet from the effects of moisture and oxygen in the air, increase stability, and can cover up bad smell, and has less negative side effects than sugar coating. In order to ensure the quality of the tablet and take it conveniently, a suitable coating material is wrapped on the surface of the tablet core after co...

Claims

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Application Information

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IPC IPC(8): A61K36/537A61K9/30A61K9/32A61P9/10
Inventor 何广政
Owner LUOYANG SHUNSHI PHARMA
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