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External patch for auxiliary treatment of insomnia

A technology of adjuvant therapy and patch, applied in the field of external patch for adjuvant treatment of insomnia, to achieve the effect of good skin followability, convenient use, and good therapeutic effect

Active Publication Date: 2014-02-05
刘秀芹
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It has been reported that the preparation technology of meridian patch cataplasm is studied, but at present, there is no external patch of traditional Chinese medicine cataplasm for treating insomnia in China.

Method used

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  • External patch for auxiliary treatment of insomnia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] An external patch for auxiliary treatment of insomnia, the preparation method of which comprises the following steps:

[0019] Step 1) Extraction of ointment: Weigh 100g of Coptidis rhizome and 50g of Caulis persicae, firstly mix Coptidis and Caulis persica evenly, add 70% ethanol solution with mass fraction 8 times the volume of medicinal materials, and extract at 80°C under reflux in water bath Twice, extracting for 2 hours each time, collecting the reflux liquid for suction filtration, each time the reflux liquid needs to be suction filtered twice to remove the residue; place the filtrate on a rotary evaporator at 50°C and a pressure of 0.09MPa to concentrate to a slurry;

[0020] Step 2) Preparation of patch: take 10g of concentrated ointment and heat it in a water bath, add it to a mixture of 100g of glycerol, 12.2g of propylene glycol, and 3.3g of cinnamon powder, stir and mix to form phase A, and then add 15g of sodium polyacrylate, Glycol 0.7g, EDTA 0.2g, stir a...

Embodiment 2

[0023] An external patch for auxiliary treatment of insomnia, the preparation method of which comprises the following steps:

[0024] Step 1) Extraction of ointment: Weigh 200g of Coptidis Rhizome and 100g of Caulis Norifolia, first mix Coptidis Rhizoma and Caulis Phytophthora evenly, add an ethanol solution with a mass fraction of 8 times the volume of medicinal materials, and extract at 87°C under reflux in a water bath Twice, extracting for 2 hours each time, collecting the reflux liquid for suction filtration, each time the reflux liquid needs to be suction filtered twice to remove the residue; place the filtrate on a rotary evaporator at 45°C and a pressure of 0.09MPa to concentrate to a slurry;

[0025] Step 2) Preparation of patch: take 20g of concentrated ointment and heat it in a water bath, add it to a mixture of 200g of glycerin, 24.4g of propylene glycol, and 6.6g of cinnamon powder, stir and mix to form phase A, and then add 30g of sodium polyacrylate, Glycol 1.4g...

Embodiment 3

[0028] An external patch for auxiliary treatment of insomnia, the preparation method of which comprises the following steps:

[0029] Step 1) Extraction of the ointment: Weigh 400g of Coptidis Rhizoma and 200g of Caulis Norifolia, mix Coptidis Rhizome and Caulis Norifolia evenly, add 70% ethanol solution with a mass fraction 8 times the volume of medicinal materials, and extract under reflux in a water bath at 85°C Twice, extracting for 2 hours each time, collecting the reflux liquid for suction filtration, each time the reflux liquid needs to be suction filtered twice to remove the residue; place the filtrate on a rotary evaporator at 40°C and a pressure of 0.10 MPa to concentrate to a slurry;

[0030] Step 2) Preparation of patch: Take 30g of concentrated ointment and heat it in a water bath, add it to a mixture of 300g of glycerol, 36.6g of propylene glycol, and 13.2g of cinnamon powder, stir and mix to form phase A, and then add 45g of sodium polyacrylate, Glycol 2.1g, EDT...

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Abstract

The invention discloses an external patch for auxiliary treatment of insomnia. According to the external patch, coptis having the function of clearing heart fire, cinnamon having the functions of warming Yang and tonifying kidney and tuber fleeceflower stem having the functions of nourishing heart, dredging collaterals and soothing nerves are selected, the components are extracted and processed and are added into a hollow substrate to prepare a cataplasm for application, the external patch is adhered on Yongquan acupoint, Neiguan acupoint and Sanyinjiao acupoint in combination with an acupoint application therapy to treat insomnia, the external patch has the advantages of convenience for use, few side effect, good skin compatibility and the like and has a good curative effect on patients with mild to moderate insomnia.

Description

technical field [0001] The invention belongs to the research field of traditional Chinese medicine preparation technology, and in particular relates to an external patch for auxiliary treatment of insomnia. Background technique [0002] Insomnia is a common disease that seriously endangers physical and mental health. In recent years, with the rapid development of my country's society, the number of patients with insomnia has increased significantly, which has seriously affected social productivity and the physical and mental health of the people, and brought enormous pressure to the patients themselves, their families, and the society. In the treatment of insomnia, although the current cognitive psychotherapy and drug therapy can help patients achieve some curative effects, most patients are afraid of adverse reactions such as liver and kidney toxicity and dependence of sedative hypnotic drugs. The use of traditional Chinese medicine to prevent and treat insomnia is a major...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61K9/70A61P25/20
Inventor 黄俊山张一帆
Owner 刘秀芹
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