Traditional Chinese medicine preparation for treating migraine with obstruction of collaterals by blood stasis and preparation method thereof

A technology of traditional Chinese medicine preparations and blood stasis blocking collaterals, which can be applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and drug combinations, etc., can solve the problems such as difficulty in obtaining satisfactory curative effects, and achieve the effects of less toxic and side effects and definite curative effects.

Inactive Publication Date: 2014-03-19
陈红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Western medicine generally uses anti-inflammatory, analgesic and calcium channel blockade methods in the treatment of migraine, but it is difficult to achieve satisfactory clinical results

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0041] The present invention also provides the preparation method of above-mentioned Chinese medicine preparation, and the dosage form of described Chinese medicine preparation is capsule, and its preparation method comprises the following steps:

[0042] The first step is to mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 55-65% that is 2-4 times the mass of the mixture, heat and reflux for 2-4 hours, extract, and filter to obtain the first extraction. liquid; the dregs obtained by filtration are then added ethanol with an alcohol concentration of 55-65% relative to the mass of the dregs, heated to reflux for 45 minutes to 1 hour, extracted, and filtered to obtain the second extract; the first extract The liquid and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0043] In the second step, the dry paste obtain...

Embodiment 1

[0050] Embodiment 1: Capsules

[0051] Take Gangmeigen 120g, Luhuo 270g, Donglingcao 80g, Maple Pear 310g, Basil 120g, Rauwolfia 60g, Bashanhu 90g, Lemongrass 120g, Red Hen Grass 170g, Zushima 70g, Zoumafeng 180g, Youcao 90g, laurel root 130g and triangular wind 220g;

[0052] Prepare as follows:

[0053] The first step is to mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 65% that is 4 times the mass of the mixture, heat and reflux for 3 hours, extract, and filter to obtain the first extract; Then add ethanol with an alcohol concentration of 65% relative to the quality of the dregs, heat and reflux for 45 minutes, extract, and filter to obtain the second extract; combine the first extract and the second extract, and concentrate under reduced pressure to remove ethanol solvent, dried to obtain a dry paste;

[0054] In the second step, the dry paste obtained in the first step is placed in a sup...

Embodiment 2

[0056] Embodiment 2: powder

[0057] Take 140g of plum root, 280g of deer humerus, 70g of winter grass, 330g of maple pear, 140g of basil, 80g of Rauwolfia, 70g of Bashan tiger, 130g of lemongrass, 190g of red hen grass, 80g of ancestral hemp, 160g of Zoumafeng, Youcao 60g, laurel root 110g and triangular wind 240g;

[0058] Prepare as follows:

[0059] The first step: mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 70% that is 4 times the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 70% that is 2 times the mass of the medicinal residues, heat and reflux for 1 hour, extract, and filter to obtain the second extract; combine the first extract and the second extract, and concentrate under reduced pressure to remove Ethanol solvent, drying, obtains dry paste;

[0060] The second st...

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PUM

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Abstract

The invention provides a traditional Chinese medicine preparation for treating migraine with obstruction of collaterals by blood stasis and a preparation method thereof. The traditional Chinese medicine preparation comprises the following raw material medicines: radix ilicis asprellae, rhynchosia volubilis, herba rabdosiae, root of dentiferous dendropanax, sweet basil herb, rauvolfia verticillate, Indian nightshade root, lemongrass herb, abrus herb, herba lagotis, six-eared blumea, leersia hexandra, root of artocarpus hypargyreus and Chinese ivy stem. The traditional Chinese medicine preparation provided by the invention has the functions of activating blood and dissolving stasis and dredging collaterals and relieving pain, and realizes an exact curative effect on migraine with obstruction of collaterals by blood stasis while causing few toxic and side effects.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine preparation for treating migraine of blood stasis blocking collaterals type and a preparation method thereof. Background technique [0002] Migraine is a common chronic neurovascular disease. It usually occurs in children and adolescence, and reaches the peak in young and middle-aged adults. It is more common in women, and the ratio of male to female patients is about 1:2~3. % to 10%, often with a genetic background. Migraine is a recurrent disease with a tendency to develop in families. It is manifested as paroxysmal hemilateral throbbing headache, accompanied by nausea, vomiting and photophobia, which recurs after a period of rest. Headache relief in a quiet, dark environment or after sleep. It may be accompanied by neurological and mental dysfunction before or during the onset of headache. ...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P25/06
Inventor 陈红姜秀娟
Owner 陈红
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