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Drug for improving male sperm count and motility, preparations, application and preparation method thereof

A technology for sperm count and pharmaceutical preparations, applied in pharmaceutical formulations, drug combinations, drug delivery, etc., can solve the problems of high dosage, many toxic and side effects, and insufficient curative effect, and achieves the goal of enhancing the quantity and vitality and improving the quality of male sperm. Effect

Active Publication Date: 2014-05-07
GUIZHOU SHENQI PHARMA RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are relatively few types of medicines currently used clinically to treat low sperm motility and low sperm count, and the therapeutic effects are not obvious, and the single application of chemical medicines has a single purpose of treatment, and there are many toxic and side effects. , can gradually improve fundamentally, but its application in the market has certain limitations due to its insufficient rapid curative effect, unclear mechanism of action of active ingredients, and large dosage. The combination of Chinese and Western medicines with small doses and no side effects has attracted more and more attention, and has broad market prospects.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0074] Embodiment 1: the preparation of A1 syrup

[0075] Prescription: Pecan kernel 75g, Luo Han Guo 54g, zinc gluconate 60g, mannan peptide 7g

[0076] Preparation method: Grind hickory nuts into fine powder for later use, decoct Luo Han Guo with 5 times the amount of water for 3 times, each time for 0.5 hours, combine the decoction, filter, and concentrate the filtrate under reduced pressure to an extract with a density of 1.05 at 50°C; Fully mix Luo Han Guo extract, pecan kernel powder, zinc gluconate and mannan peptide, take another appropriate amount of sucrose into boiling water to dissolve evenly, filter to make simple syrup, and add appropriate amount of simple syrup to the above drug mixture Make the final sugar content 70%, add 0.6% sodium benzoate, heat to dissolve in a water bath, add water to 5000ml, stir well, filter, potting, and obtain the syrup.

[0077] Usage and dosage: oral administration, 10ml each time, 3 times a day, 30 days as a course of treatment. ...

Embodiment 2

[0078] Embodiment 2: the preparation of A2 syrup

[0079] Prescription: 60g of pecan kernels, 43g of Luo Han Guo, 48g of zinc gluconate, 5g of mannan peptide

[0080] Preparation method: Grind hickory kernels into fine powder for later use, decoct Luo Han Guo with 10 times the amount of water twice, for 2 hours each time, combine the decoction, filter, and concentrate the filtrate under reduced pressure to an extract with a density of 1.1 at 50°C; Fully mix Luo Han Guo extract, pecan kernel powder, zinc gluconate and mannan peptide, take another appropriate amount of sucrose into boiling water to dissolve evenly, filter to make simple syrup, and add appropriate amount of simple syrup to the above drug mixture Make the final sugar content 60%, add 0.4% sodium benzoate, heat to dissolve in a water bath, add water to 5000ml, stir well, filter, potting, and obtain the syrup.

Embodiment 3

[0081] Embodiment 3: the preparation of B1 oral liquid

[0082] Prescription: 90g pecan kernels, 65g Luo Han Guo, 72g zinc gluconate, 9g mannan peptide

[0083] Preparation method: Grind hickory kernels into fine powder for later use, decoct Luo Han Guo with 6 times the amount of water twice, each time for 1.5 hours, combine the decoction, filter, and concentrate the filtrate under reduced pressure to an extract with a density of 1.1 at 50°C; Fully mix Luo Han Guo extract, pecan kernel powder, zinc gluconate and mannan peptide, take another appropriate amount of sucrose into boiling water to dissolve evenly, filter to make simple syrup, and add appropriate amount of simple syrup to the above drug mixture Make the final sugar content 50%, add 0.3% sodium benzoate, boil to dissolve, add water to 5000ml, stir well, filter, potting, and then the oral liquid is obtained.

[0084] Usage and dosage: oral administration, 10ml each time, 3 times a day, 30 days as a course of treatment...

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Abstract

The invention relates to a drug for improving male sperm count and motility, preparations, application and a preparation method thereof. The drug and its preparations are made of pecan kernels, Siraitia grosvenorii, zinc gluconate and mannan. Auxiliary materials are added into the medicines to prepare pharmaceutical preparations according to conventional preparation processes. Application of the drug and its preparations provided by the invention to enhancement of male sperm count and motility and improvement of sperm quality can achieve unexpected therapeutic effects. Therefore, the drug and its preparations provided by the invention can be another choice for treatment of male infertility.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations for treating infertility, in particular to a medicine for improving the quantity and vitality of male sperm and its preparation, application and preparation method. Background technique [0002] Semen is composed of sperm and seminal plasma, of which sperm account for about 5%, and the rest is seminal plasma. In addition to water, fructose, protein and fat, it also contains a variety of enzymes and inorganic salts. Sperm are produced by the testes, and seminal plasma is secreted by the prostate, seminal vesicles, and bulbourethral glands. Seminal plasma contains fructose and protein, which are nutrients for sperm. In addition, seminal plasma also contains prostaglandins and some enzymes. Normal semen is milky white, light yellow, or colorless. The number of sperm per milliliter of semen is generally between 60 million and 200 million. Motile sperm accounted for more than 60%...

Claims

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Application Information

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IPC IPC(8): A61K36/52A61K38/14A61K9/08A61K9/20A61P15/08
Inventor 张芝庭张涛涛
Owner GUIZHOU SHENQI PHARMA RES INST
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