Emulsion with functions of persistently moisturizing and removing wrinkles and preparation method thereof

A technology of emulsion and action, which is applied in the direction of dressing preparations, skin care preparations, pharmaceutical formulations, etc., can solve the problems of skin burden, waste of active ingredients, etc., and achieve the effect of increasing the barrier, reducing the number of times of use, and facilitating long-term preservation

Active Publication Date: 2014-06-04
广州智园生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are many types of moisturizing and anti-wrinkle products in the cosmetics market, but the long-lasting and slow-release effect is far from expected, and regular use of such products will burden the skin and waste active ingredients

Method used

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  • Emulsion with functions of persistently moisturizing and removing wrinkles and preparation method thereof
  • Emulsion with functions of persistently moisturizing and removing wrinkles and preparation method thereof
  • Emulsion with functions of persistently moisturizing and removing wrinkles and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] (1) Weigh 0.25g of Span-80 and 1.25g of polyoxyethylene (40) hydrogenated castor oil, 1.25g of PEG-400 and 0.3g of hexagonal mesoporous silicon, stir and mix, and form a mixed emulsifier after ultrasonication for 10 minutes;

[0034] (2) Weigh 0.1g of five-membered peptide, 0.14g of jojoba oil and 0.86g of isopropyl myristate, mix well and heat to 40°C to form an oil phase;

[0035] (3) Weigh 0.1g of sodium hyaluronate and 0.5g of deionized water, and mix them evenly to form an inner water phase;

[0036] (4) Stir and mix the oil phase in step (2) and the mixed emulsifier in step (1), then add the inner water phase drop by drop to form w / o colostrum, continue to drop by drop slowly under the stirring state of 800rpm Add 5.15g of deionized water to form a w / o / w emulsion, finally add 0.1g of triethanolamine to adjust the pH of the emulsion to 6.10, and continue stirring for 12 hours to obtain an emulsion with lasting moisturizing and wrinkle-removing effects.

Embodiment 2

[0038] (1) Weigh 2g of Tween-80, 1.5g of propylene glycol and 0.4g of hexagonal mesoporous silicon, stir and mix, and form a mixed emulsifier after ultrasonication for 10 minutes;

[0039] (2) Weigh 0.1g of five-membered peptide, 0.33g of olive oil and 0.67g of isopropyl myristate, mix well and heat to 40°C to form an oil phase;

[0040] (3) Weigh 0.1g of sodium hyaluronate and 0.5g of deionized water, and mix them evenly to form an inner water phase;

[0041] (4) Stir and mix the oil phase in step (2) and the mixed emulsifier in step (1), then add the inner water phase drop by drop to form w / o colostrum, continue to drop by drop slowly under the stirring state of 700rpm Add 4.35g of deionized water to form a w / o / w emulsion, and finally add 0.05g of citric acid to adjust the pH of the emulsion to 6.83, and continue stirring for 12 hours to obtain an emulsion with long-lasting moisturizing and wrinkle-removing effects.

Embodiment 3

[0043] (1) Weigh 0.5g of Span-80 and 1.5g of Tween-80, 1.5g of propylene glycol and 0.4g of hexagonal mesoporous silicon, stir and mix, and form a mixed emulsifier after ultrasonication for 10 minutes;

[0044] (2) Weigh 0.1g pentavalent peptide, 0.14g almond oil and 0.86g isopropyl palmitate, mix well and heat to 40°C to form an oil phase;

[0045] (3) Weigh 0.1g of sodium hyaluronate and 0.5g of deionized water, and mix them evenly to form an inner water phase;

[0046] (4) Stir and mix the oil phase in step (2) and the mixed emulsifier in step (1), then add the inner water phase drop by drop to form w / o colostrum, continue to drop by drop slowly under the stirring state of 800rpm Add 4.35g of deionized water to form a w / o / w emulsion, and finally add 0.05g of sodium hydroxide to adjust the pH of the emulsion to 6.20, and continue stirring for 12 hours to obtain an emulsion with lasting moisturizing and wrinkle-removing effects.

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Abstract

The invention discloses an emulsion with functions of persistently moisturizing and removing wrinkles and a preparation method thereof. The emulsion belongs to a w / o / w structure, and meanwhile loads a moisturizing active component and a wrinkle-resistant active component. The emulsion comprises the following components: moisturizing and wrinkle-resistant active components, an emollient, a surfactant, a cosurfactant, mesoporous silicon, a pH adjustor and deionized water. A shell is formed at the oil-water interface of the mesoporous silicon due to characteristic that structurally, oxygen atoms easily form hydrogen bonds with hydrophyllic terminals of the amphipathic surfactant, so that the release time of the active components is postponed. The emulsion with functions of persistently moisturizing and removing wrinkles provided by the invention has very good stability, is simple in preparation method, and has an abroad market when being applied to the field of cosmetics.

Description

technical field [0001] The invention relates to a cosmetic emulsion, in particular to an emulsion with long-lasting moisturizing and wrinkle-removing effects and a preparation method thereof. Background technique [0002] Anti-wrinkle and anti-aging has become one of the hotspots in medical science research, and it is the top priority of the cosmetics industry. According to the survey of the cosmetics market in the United States, the share of moisturizing and anti-wrinkle cosmetics on the market has accounted for more than half. With the increase of the aging population in China, the domestic demand for moisturizing and anti-wrinkle skin care products is increasing. [0003] The appearance of wrinkles is a sign of skin aging, and skin aging is a part of body aging, and the aging of the body is most obvious on the skin. Although aging is a natural law, it is also affected by other factors, such as living habits, ultraviolet rays, frequent exaggerated expressions, lack of exe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/06A61K8/25A61Q19/00A61Q19/08
Inventor 魏坤冯海湾
Owner 广州智园生物科技有限公司
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