Traditional Chinese medicine for treating schizophrenia and preparation method thereof

A technology of traditional Chinese medicine and medicinal materials, which is applied in the field of pharmacy, can solve the problems of low treatment efficiency, decreased patient will, and large side effects, and achieve the effects of simple production process, short healing time, and small toxic and side effects

Inactive Publication Date: 2014-06-18
李佃场
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] (4) Disorders of will and behavior: Most patients have decreased or even lack of will, manifested as reduced activities, being alone, passive behavior, and lack of due enthusiasm and initiative Sexuality, loss of interest in work and study, no concern for the future, no clear plans for the future, some patients may have some plans and intentions, but they are rarely implemented
[0020]2. Internal resistance of phlegm and dampness
[0040]At present, Western medicine treats schizophrenia, and antipsychotic drug treatment is the preferred treatment for schizophrenia. The curative effect is not good, and the treatment efficiency is low. It can only play a controlling role , Once the dose is insufficient or the drug is stopped, it will relapse, with relatively large side effects, strong dependence and drug resistance

Method used

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Examples

Experimental program
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Effect test

preparation example Construction

[0103] Wherein, when the dosage form of described Chinese medicine is honey refining pill, its preparation method comprises the following steps:

[0104] Step 1: First mix the golden brush handle, iron-coated gold, uncaria root and gardenia according to the stated ratio, and then distill and crystallize to obtain a powder;

[0105] Step 2: Take the remaining raw materials and mix them according to the ratio, add 2-6 times the amount of 83-94% ethanol to soak for 1-2 hours, heat and extract twice, each time for 1-1.5 hours, and combine the extracts , 124-150 mesh filtration, and then ultrafiltration through an ultrafiltration column with a cut-off molecular weight of 4400-98000, and the ultrafiltrate is concentrated under reduced pressure to an extract with a relative density of 1.04 at 87°C, which becomes component 1;

[0106] Step 3: Soak the dregs of traditional Chinese medicine in step 2 with 4-6 times the amount of water for 1-2.5 hours, extract once in 1.5-2 hours, concen...

Embodiment 1

[0119] Embodiment 1 honey refining pill of the present invention

[0120]Take 27g of gold brush, 16g of iron-clad gold, 25g of uncaria root, 23g of gardenia, 28g of tempeh, 32g of skullcap, 24g of Prunella vulgaris, 12g of mulberry leaves, 15g of angelica, 19g of Cyperus cyperus, 32g of cassia seed, 26g of horsetail, and 20g of dogwood , Green Box 30g, Gujingcao 24g, Mimenghua 23g, Cerulean 17g, Trichosanthes 18g, Zhuru 28g, Bamboo Lek 17g, Tianzhuhuang 16g, Magnet 19g, Divine Comedy 33g, Keel 22g, Valerian 8g, Polygala 26g, Albizia Julibrissin 11g, Zibei tooth 16g, Licorice 14g and Shichangpu 8g.

[0121] Its preparation method comprises the following steps:

[0122] Step 1: First mix the golden brush handle, iron-coated gold, uncaria root and gardenia according to the stated ratio, and then distill and crystallize to obtain a powder;

[0123] Step 2: Take the remaining raw materials and mix them according to the stated ratio, add 94% ethanol which is 4 times the amount of ...

Embodiment 2

[0127] Embodiment 2 Granules of the present invention

[0128] Take 33g of gold brush handle, 21g of iron-clad gold, 19g of Uncaria root, 28g of gardenia, 25g of tempeh, 26g of skullcap, 27g of Prunella vulgaris, 19g of mulberry leaves, 25g of angelica, 17g of Cyperus cyperus, 30g of cassia seed, 15g of horsetail, 25g of dogwood , Green Box 26g, Gujingcao 19g, Mimenghua 26g, Cerulean 21g, Trichosanthes 23g, Zhuru 34g, Bamboo Lek 21g, Tianzhuhuang 18g, Magnet 29g, Divine Comedy 35g, Keel 27g, Valerian 12g, Polygala 33g, Albizia Julibrissin 19g, Zibei tooth 22g, Licorice 20g and Shichangpu 10g.

[0129] Its preparation method comprises the following steps:

[0130] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 95% that is 5 times that of the mixture, heat to boiling and reflux for 4 hours, filter, and use percolation method at a rate of 2ml per minute. Percolation, collect the percolation liquid, then concen...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating schizophrenia and a preparation method thereof. The traditional Chinese medicine comprises the following raw herbal materials: cladonia fallax abbayes, berchemia lineate, uncaria rhynchophylla root, jasmine, fermented soybean, scutellaria baicalensis, square-stem, folium mori, angelica sinensis, rhizoma cyperi, semen cassia, scouring rush, dogwood, semen celosiae, pipewort, butterflybush flower, motherwort fruit, fructus trichosanthis, bamboo shavings, bamboo juice, tabasheer, magnetite, medicated leaven, keel, valerian, polygala tenuifolia, cortex albiziae, concha mauritiae arabicae, liquorice and rhizoma acori graminei. The traditional Chinese medicine has the beneficial effects that the traditional Chinese medicine disclosed by the invention adopts different properties of traditional Chinese medicinal materials, is rigorous in compatibility, can directly reach the focus of infection by treatment based on syndrome differentiation, has the effects of purging liver-fire, and removing phlegm and inducing resuscitation, is short in recovery time, not easy to reappear after recovery, small in toxic and side effects, proper in taste, easy to accept by a patient, and simple and convenient in manufacturing process; the drug is easy to manufacture and low in cost.

Description

[0001] technical field [0002] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for treating schizophrenia and a preparation method thereof Background technique [0003] Schizophrenia is a group of severe mental illnesses of unknown etiology, mostly in young adults with slow or subacute onset, clinically manifested as a syndrome with various symptoms, involving obstacles in perception, thinking, emotion, and behavior and incoordination of mental activity. Patients generally have clear consciousness and basically normal intelligence, but some patients may experience cognitive impairment during the course of the disease. The course of the disease is generally protracted, showing recurrent attacks, aggravation or deterioration, and some patients eventually develop decline and mental disability, but some patients can maintain recovery or basically recovery after treatment. [0004] The basic causes mainly include the fo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/20A61K9/16A61P25/18A61K33/26A61K35/02A61K35/618
Inventor 李佃场梁轶聪
Owner 李佃场
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