A kind of chitosan quaternary ammonium salt coupling agent and preparation method thereof

Abstract

The invention discloses a chitosan quaternary ammonium salt couplant and a preparation method thereof. The chitosan quaternary ammonium salt couplant is prepared from 0.1-0.9wt% of Carbomer 941, 0.5-6wt% of phenoxyethanol, 0.01-1.0wt% of hydrochloric acid, 0.1-0.8wt% of chitosan quaternary ammonium salt, 1.2-10wt% of triethanolamine, 2-20wt% of a humectant and the balance distilled water. The chitosan quaternary ammonium salt couplant has the advantages of good bactericidal effects, good environmental performances, no carcinogenesis on the human body, clarification, transparency, alcohol fragrance, good homogeneity and good fineness.

Description

technical field [0001] The invention relates to the field of medical medicaments, in particular to a medical coupling agent, in particular to a chitosan quaternary ammonium salt coupling agent and a preparation method thereof. Background technique [0002] As we all know, medical couplant is a kind of drug applied on the skin during ultrasonic examination. First, the ultrasonic couplant can fill the tiny gaps between the contact surfaces, so as to prevent the tiny amount of air in the gaps from affecting the penetration and detection results of ultrasound; Secondly, through the transitional effect of the coupling agent, the acoustic impedance difference between the probe and the skin is reduced, thereby reducing the reflection loss of ultrasonic energy at this interface; Reduced so that the probe can slide and explore flexibly. [0003] Most of the medical coupling agents used in clinical B-ultrasound are polymer water-soluble gel preparations, and their chemical components...