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Oral liquid for relieving physical fatigue and improving sleep and preparation method thereof

A technology for relieving physical fatigue and improving sleep. It is applied in medical preparations containing active ingredients, pharmaceutical formulas, and food science. It can solve problems such as easy-to-contaminate bacteria, inability to adopt high-temperature sterilization methods, and poor quality controllability. The effect of relieving physical fatigue, improving sleep, and broad market prospects

Active Publication Date: 2017-01-04
HARBIN PHARM GROUP SANJING PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Royal jelly is a highly susceptible substance that is sensitive to heat and cannot be sterilized by conventional high temperature methods. Therefore, the liquid preparations containing this substance have poor quality controllability and are prone to bacterial contamination.

Method used

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  • Oral liquid for relieving physical fatigue and improving sleep and preparation method thereof
  • Oral liquid for relieving physical fatigue and improving sleep and preparation method thereof
  • Oral liquid for relieving physical fatigue and improving sleep and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The composition of this product is: every 100ml contains 10g of Acanthopanax senticosus extract, 5g of royal jelly, 50g of honey, 0.5g of sodium citrate, and 5g of ethanol.

[0024] The specific preparation process is:

[0025] 1. Heat and boil purified water for 30 minutes to prepare sterilized water.

[0026] 2. Take the formula amount of honey and heat it in a water bath, keep stirring, control the temperature at 60°C, process and filter it with a 120-mesh filter, pass the filtered honey through a heat exchanger, raise the honey temperature to 75°C, keep it for 5 minutes, and then put The honey is pressed into the cooling system to lower the honey temperature to 60°C; the sterilized honey is sent to the thin-film vacuum evaporator at a temperature of 50°C for 3 minutes.

[0027] 3. Take the concentrated liquid of Acanthopanax acanthopanax extract and pass it through the D392 macroporous resin (the ratio of extract to resin is about 3:1). The adsorption rate is 2BV / h...

Embodiment 2

[0032] The composition of this product is: every 100ml contains 5g of Acanthopanax senticosus extract, 1g of royal jelly, 10g of honey, 0.3g of sodium citrate, and 3g of ethanol.

[0033] The specific preparation process is:

[0034] 1. Heat and boil purified water for 30 minutes to prepare sterilized water.

[0035] 2. Take the formula amount of honey and heat it in a water bath, stirring constantly, the temperature is controlled at 58±2°C, processed and filtered with a 120-mesh filter, the filtered honey passes through a heat exchanger, and the temperature of the honey is raised to 80±5°C, and kept at 10 Minutes, then press the honey into the cooling system to lower the honey temperature to 58±2°C; send the sterilized honey into a thin-film vacuum evaporator at a temperature of 50°C for 5 minutes.

[0036] 3. Take the concentrated liquid of Acanthopanax acanthopanax extract and pass it through the D392 macroporous resin (the ratio of extract to resin is about 3:1). The adso...

Embodiment 3

[0041] The composition of this product is as follows: every 100ml contains 7g of Acanthopanax senticosus extract, 2g of royal jelly, 15g of honey, 0.5g of sodium citrate, and 10g of ethanol.

[0042] The specific preparation process is:

[0043] 1. Heat and boil purified water for 30 minutes to prepare sterilized water.

[0044] 2. Take the formula amount of honey and heat it in a water bath, keep stirring, control the temperature at 55°C, process and filter it with a 120-mesh filter, pass the filtered honey through a heat exchanger, raise the honey temperature to 100°C, keep it for 5 minutes, and then put The honey is pressed into the cooling system to lower the honey temperature to 55°C; the sterilized honey is sent to the thin-film vacuum evaporator at a temperature of 50°C for 5 minutes.

[0045] 3. Take the concentrated liquid of Acanthopanax acanthopanax extract and pass it through the D392 macroporous resin (the ratio of extract to resin is about 3:2). The adsorption r...

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Abstract

The invention relates to an oral liquid capable of relieving physical fatigue and improving sleep and a preparation method thereof. The composition is as follows: every 100 volume fractions contains 0.5-20 parts by mass of Acanthopanax senticosus extract, 0.5-10 parts by mass of royal jelly, 10-80 parts by mass of honey, 0.1-5 parts by mass of sodium citrate, and 0.2 parts by mass of ethanol. -20 parts by mass. The present invention effectively purifies the active ingredients in Acanthopanax extractum during the preparation process, guarantees the quality and effect of honey to the greatest extent, adopts heat preservation and sterilization to ensure product quality, makes the drug effect of the prepared product more significant, and reduces the interference of impurities on the curative effect and the In order to prevent the occurrence of side effects, royal jelly and honey are optimized to make the product more stable and reliable in quality, reduce the stimulation of the product to the gastrointestinal tract, and enhance its health care effect.

Description

[0001] (1) Technical field: [0002] The invention relates to a preparation method of an oral liquid capable of relieving physical fatigue and improving sleep. [0003] (two) background technology: [0004] There are various products for relieving physical fatigue in the market, the preparation process is complicated, and the effects are uneven. Among them, there are many products containing Acanthopanax and royal jelly, which are mainly solid preparations. The present invention is an oral liquid, which has the advantages of fast absorption, high bioavailability, and convenient administration, and is especially suitable for some people who have difficulty swallowing. The Acanthopanax extract contained in this product is completely eluted with D392 macroporous resin to completely elute the active ingredient total saponin, eliminate the interference of other ineffective ingredients on the effect, reduce adverse reactions and side effects, and effectively improve the anti-fatigue ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L2/38A23L33/00A61K36/254A61K9/08A61P39/00A61P25/20
Inventor 秦雅英刘春凤郭艳波刘洋
Owner HARBIN PHARM GROUP SANJING PHARMACEUTICAL CO LTD
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