Preparation method of lactobacillus paracasei probiotics tablet of bifidobacteria producing bile salt hydrolase

Abstract

The invention relates to bifidobacteria producing bile salt hydrolase and a preparation method of a probiotics tablet which has the function of reducing serum cholesterol, and the method is suitable for producing microecological preparations such as functional probiotics lactic acid bacteria living bacteria. The formula of the probiotics tablet provided by the invention comprises lactobacillus paracasei KL1-Liu probiotics powder and auxiliary materials such as skim milk powder, fructo-oligose, xylitol, cane sugar, citric acid, microcrystalline cellulose and maltodextrin. The preparation method comprises the following steps: performing processes such as activation, enlarged cultivation, high-density fermentation, concentration by centrifuging, freeze-drying protective additive addition, pre-freezing and freezing on lactobacillus paracasei KL1-Liu CGMCC No. 7029 of the bifidobacteria producing bile salt hydrolase, thereby preparing the probiotics powder; and mixing the crushed and sieved auxiliary materials with the probiotics powder and compressing to prepare the probiotics tablet. The probiotics tablet provided by the invention has good storage stability and the expiration date of living bacteria at 4 DEG C is at least over 1 year, so that the tablet still has the health function of reducing serum cholesterol. According to the probiotics tablet prepared by the invention, the raw materials are easily available, the process is simple, the preparation period is short and the operation is simple. The tablet is suitable for industrial production.

Description

technical field [0001] The invention relates to a preparation method of a probiotic tablet that produces bile salt hydrolyzing enzyme and has the effect of lowering serum cholesterol, and is suitable for the production of functional probiotic live lactic acid bacteria preparations (tablet type, powder type) and other microecological preparations. Background technique [0002] The Lactobacillus paracasei (Lactobacillus paracasei) KL1-Liu involved in the present invention is a probiotic lactic acid bacterium that produces bile salt hydrolysis enzyme and has the effects of lowering serum cholesterol and regulating intestinal flora balance, etc. . [0003] Probiotics refer to a class of microorganisms that improve the microecological balance of specific parts of the host through intestinal colonization and have several other beneficial physiological functions. They can improve the ecological balance of intestinal microorganisms, control intestinal infection, reduce serum choles...

AI Technical Summary

Problems solved by technology

Although the above-mentioned patents and documents have reports on the use of probiotics to prepare tablet-type foods, about the preparation of probiotics by using Lactobacillus paracasei KL1-Liu, which is isolated and screened from the bile salt hydrolyzing enzyme in Tibetan mushrooms and has the effect of lowering serum cholesterol. The method of bacteria sheet has not yet been seen in relevant literature reports and patent reports at home and abroad

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