Composition, use and health care product
A technology for compositions and health care products, which can be used in drug combinations, medical preparations containing active ingredients, applications, etc., and can solve problems such as unsatisfactory effects of therapeutic drugs or health care products.
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Embodiment 1
[0038] Embodiment 1 Animal test
[0039] Dose protection of main raw materials:
[0040]
[0041]
[0042] Effects on alcohol-induced acute gastric mucosal injury rat model:
[0043] Select SPF grade SD rats, male, weighing 180-220g. Every batch of animals is randomly divided into 8 groups by body weight, including normal control group, model control group, single drug group and test group (table 1), every group of 10, each group is all by oral gavage of 10ml / kg, 1 times / day. Rats were fasted without food and water for 24 hours before modeling. Except for the normal control group, all other groups were administered once to create models of acute gastric mucosal injury. In order to observe the cumulative effect of the drug effect, another 80 rats were administered in the same way at 9 am every day for 7 days. On the 6th day, the rats were fasted for 24 hours. At 9 a.m. on the 7th day, the model was established 1 hour after administration. One hour after modeling, the...
Embodiment 2
[0054] The preparation of embodiment 2 tablet
[0055]
[0056]
[0057] Weigh Hericium erinaceus or Hericium erinaceus extract, chitosan, wheat oligopeptide, microcrystalline cellulose, mannitol, crospovidone, magnesium stearate, silicon dioxide in the formula A certain amount of raw and auxiliary materials are put into the mixer and mixed for 20-30 minutes.
[0058] The above mixture is compressed into tablets with a tablet machine, 1 g / tablet, to obtain plain tablets.
[0059] Weigh the coating agent according to the formula, adjust it to a suitable solid content, and stir it in a paddle pan for 30 to 45 minutes; after the stirring is completed, coat the plain tablet until the surface of the tablet is basically formed into a film and the color is consistent.
Embodiment 3
[0060] The preparation of embodiment 3 tablet
[0061]
[0062]
[0063] Weigh Hericium erinaceus or Hericium erinaceus extract, chitosan, wheat oligopeptide, microcrystalline cellulose, mannitol, crospovidone, magnesium stearate, silicon dioxide in the formula A certain amount of raw and auxiliary materials are put into the mixer and mixed for 20-30 minutes.
[0064] The above mixture is compressed into tablets with a tablet machine, 1 g / tablet, to obtain plain tablets.
[0065] Weigh the coating agent according to the formula, adjust it to a suitable solid content, and stir it in a paddle pan for 30 to 45 minutes; after the stirring is completed, coat the plain tablet until the surface of the tablet is basically formed into a film and the color is consistent.
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