Qualitative source analyzing method for lead exposure source in human blood

A source analysis and blood technology, applied in the field of exposure source analysis and determination, can solve the problems of effective identification of multi-source systems of heavy metals that cannot be deposited, qualitative evaluation of difficult pollution contributions, and large workload, and achieves good operability and practicability. , the effect of small error and simple method

Inactive Publication Date: 2015-03-04
UNIV OF SCI & TECH BEIJING
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Problems solved by technology

However, these two methods are mainly for statistical analysis and quality evaluation of the total amount and chemical forms of heavy metal elements in sediments, and cannot effectively identify and analyze the multi-source system of heavy metals in sediments, and it is difficult to make a qualitative evaluation of the pollution contribution; in addition, these two methods Both of these methods require large-scale sampling, and the workload is relatively large, so they are limited in practical application.

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  • Qualitative source analyzing method for lead exposure source in human blood
  • Qualitative source analyzing method for lead exposure source in human blood
  • Qualitative source analyzing method for lead exposure source in human blood

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[0035] There are four stable isotopes of lead in nature, which are 204 Pb, 206 Pb, 207 Pb and 208 Pb, the latter three are 238 U 235 U 232The final product of Th decay, the abundance of these three isotopes (the abundance of isotopes in nature, also known as the natural occurrence ratio, refers to the proportion of this isotope in all natural isotopes of this element, and the abundance is generally expressed in The percentage indicates that the abundance of man-made isotopes is zero. Because various isotopes are often distributed evenly in nature, the calculation of the average value is more accurate, so the atomic weights listed on the periodic table are actually weighted by the abundance of various isotopes mean) increases with time, while 204 Pb has not yet been found to be related to which radioactive isotope parent, and its absolute content does not change with time. because 238 U 235 U and 232 The decay constants of Th are different, which determines the corres...

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Abstract

The invention discloses a qualitative source analyzing method for a lead exposure source in human blood. The qualitative source analyzing method comprises the following steps: collecting an environment medium sample and a blood sample and determining the content of lead to obtain a characteristic specific value 208Pb / 206Pb; and calculating a lead isotope medium difference index D to qualitatively evaluate the lead exposure source in the blood. The invention provides the qualitative evaluation method and creatively provides the lead isotope medium difference index D; and the evaluation method, and the determination and the calculation of the lead isotope medium difference index have direct guide meaning on the evaluation of the lead exposure source in the blood. The evaluation method disclosed by the invention is applicable to the analysis and the determination of the lead exposure source in the blood, and the comprehensive evaluation is carried out on the lead exposure source in a qualitative manner; and the method is simple, objective and accurate, has the good repeatability and small errors, and has the very good operability and practicability, and scientific theoretical foundations are provided for the determination of the lead exposure source in the blood.

Description

technical field [0001] The invention relates to a method for analyzing and determining the exposure source of lead in human venous blood samples, in particular to a qualitative evaluation method for the source of lead exposure in blood. Background technique [0002] Lead is a soft slightly off-white heavy metal, which is widely distributed in the earth's crust and has a large amount of reserves. It is not degradable in the natural environment. Once mined, it will permanently exist in the living environment. Due to its unique properties such as softness, ductility, low melting point and corrosion resistance, it is one of the most widely used metals in industrial production. Current scientific research shows that not only is lead not an essential nutrient element for the human body, but excessive lead can also cause damage to multiple systems of the human body, including the nervous system, hematopoietic system, cardiovascular system, and endocrine system. Children are more s...

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Application Information

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IPC IPC(8): G01N27/62
Inventor 段小丽曹素珍赵秀阁王贝贝马瑾林春野孙承业黄楠董婷
Owner UNIV OF SCI & TECH BEIJING
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