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Traditional Chinese medicine extract and preparation method thereof

An extract and traditional Chinese medicine technology, applied in the field of traditional Chinese medicine extracts and preparation, can solve problems such as difference in effect and composition, and achieve the effects of prolonging life, inhibiting tumor and prolonging life.

Inactive Publication Date: 2015-04-29
HEILONGJIANG UNIV OF CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Therefore, the interaction between the various components will have an impact on the composition of the final extract of traditional Chinese medicine, resulting in different proportions of the extract components of traditional Chinese medicine and compatible Chinese medicine. At the same time, the components and proportions of the extract will also vary due to different extraction conditions. Different extracts with different proportions of corresponding ingredients and the effects of different extracted parts will also have differences

Method used

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  • Traditional Chinese medicine extract and preparation method thereof
  • Traditional Chinese medicine extract and preparation method thereof
  • Traditional Chinese medicine extract and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1: Preparation of the extract of Hedyotis diffusa, Scutellaria barbata and Prunella vulgaris composition

[0034] Add 30 times of the total amount of Chinese medicine (150g) to 60g of Hedyotis diffusa, 60g of Scutellaria barbata and 30g of Prunella vulgaris, and soak at room temperature for 24 hours to obtain the pretreated Chinese medicine. Boil the obtained pretreated traditional Chinese medicine at 100° C. for 1.5 hours, filter the boiled liquid with 4 layers of gauze, add 15 times of water, boil for 1 hour, filter the boiled liquid with 4 layers of gauze to remove medicinal residues. The two liquid medicines were combined and allowed to stand overnight. The next day, take the supernatant, precipitate centrifugal filtration (3000rpm, 20 minutes), combine all the supernatants, boil and concentrate to 500mL, then concentrate the supernatant to 100mL decoction in a 100°C water bath, and then use 71% The concentrated solution was precipitated with ethanol to ...

Embodiment 2

[0037] Embodiment 2: Preparation of the extract of Hedyotis diffusa and Prunella vulgaris composition

[0038]Add 30 times the total amount of traditional Chinese medicine (90 g) to 60 g of Hedyotis diffusa and 30 g of Prunella vulgaris, and soak at room temperature for 24 hours to obtain a pretreated Chinese medicine. Boil the obtained pretreated traditional Chinese medicine at 100° C. for 1.5 hours, filter the boiled liquid with 4 layers of gauze, add 15 times of water, boil for 1 hour, filter the boiled liquid with 4 layers of gauze to remove medicinal residues. The two liquid medicines were combined and allowed to stand overnight. The next day, take the supernatant, precipitate centrifugal filtration (3000rpm, 20 minutes), combine all the supernatants, boil and concentrate to 500mL, then concentrate the supernatant to 100mL decoction in a 100°C water bath, and then use 71% The concentrated solution was precipitated with ethanol to obtain ethanol precipitate and dissolved ...

Embodiment 3

[0041] Embodiment 3: Preparation of the extract of Hedyotis diffusa and Scutellaria barbata composition

[0042] Add 30 times of the total amount of traditional Chinese medicine (120 g) to 60 g of Hedyotis diffusa and 60 g of Scutellaria barbata, and soak for 24 hours at room temperature to obtain a pretreated Chinese medicine. Boil the obtained pretreated traditional Chinese medicine at 100° C. for 1.5 hours, filter the boiled liquid with 4 layers of gauze, add 15 times of water, boil for 1 hour, filter the boiled liquid with 4 layers of gauze to remove medicinal residues. The two liquid medicines were combined and allowed to stand overnight. The next day, take the supernatant, precipitate centrifugal filtration (3000rpm, 20 minutes), combine all the supernatants, boil and concentrate to 500mL, then concentrate the supernatant to 100mL decoction in a 100°C water bath, and then use 71% The concentrated solution was precipitated with ethanol to obtain ethanol precipitate and d...

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Abstract

The invention discloses a traditional Chinese medicine extract and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The preparation method comprises the following steps: heating and boiling oldenlandia diffusa, sculellaria barbata and prunella vulgaris or a traditional Chinese medicine composition of oldenlandia diffusa, sculellaria barbata and prunella vulgaris so as to obtain decoction, depositing the decoction by using 71% ethanol over night so as to obtain an alcohol soluble substance and an alcohol precipitation substance, respectively concentrating and drying the alcohol soluble substance and the alcohol precipitation substance so as to obtain crude extracts, and further separating and purifying the crude extracts, thereby obtaining an extract containing total triterpenoids and general flavones in different proportions. The traditional Chinese medicine extract disclosed by the invention has the functions of preventing tumor and prolonging the life, and the experiment shows that the average life prolonging rate can be up to 24.14%, and the average tumor inhibition rate can be up to 31.98%.

Description

technical field [0001] The invention relates to a traditional Chinese medicine extract and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Hedyotis diffusa, also known as: snake manager, Rubiaceae herb. In my country, it is mainly distributed in southern provinces such as Guangdong, Guangxi, Yunnan, and Fujian. Return stomach, large intestine meridian, small intestine meridian, cold in nature, slightly sour in taste. The root of the whole plant is used as medicine. It has the functions of clearing away heat and detoxification, clearing heat and promoting dampness, reducing inflammation and swelling, and anticancer. Hedyotis diffusa is a commonly used traditional Chinese medicine. The research hotspots are mainly the identification and extraction of effective active ingredients, pharmacological effects and mechanisms, and clinical applications. [0003] Modern research shows that its chemical co...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/748A61P39/06A61P35/00
Inventor 王艳杰李冀李明珠张雨薇姜玲王扬
Owner HEILONGJIANG UNIV OF CHINESE MEDICINE
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