A traditional Chinese medicine composition for treating systemic lupus erythematosus and its preparation method

Abstract

The invention discloses a traditional Chinese medicine composition for treating systemic lupus erythematosus. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 15-30 parts of buffalo horn sheets, 20-30 parts of oldenlandia diffusa, 10-20 parts of radix rehmanniae, 10-15 parts of fructus forsythiae, 10-20 parts of radix paeoniae alba, 10-20 parts of cortex moutan, 10-15 parts of gentiana macrophylla, 15-20 parts of lalang grass rhizome and 10-15 parts of fried atractylodes macrocephala. The invention also discloses a preparation method and application of the traditional Chinese medicine composition for treating systemic lupus erythematosus. According to the formula, the traditional Chinese medicine composition has the favorable effects of inhibiting the generation of an autoantibody, forming an immune complex and inhibiting type-III allergic reaction, has favorable analgesic and anti-inflammatory effects, has a remarkable effect in clinical treatment and has a better effect as comparison with preliminarily-researched Langchuangqing granules, in addition, the formula is simple, the dosage is reduced, and caulis sinomenii serving as a poisonous traditional Chinese medicine in the formula is removed, so that the traditional Chinese medicine composition prepared according to the formula has more advantages from the views of safety and effectiveness as comparison with the Langchuangqing granules.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating systemic lupus erythematosus made from traditional Chinese medicines and a preparation method thereof. Background technique [0002] Systemic lupus erythematosus (SLE) is a typical systemic autoimmune disease. The body produces a variety of autoantibodies accompanied by multi-system damage symptoms, usually with fever, joint pain, rash and kidney, blood, central nervous system, etc. Systemic involvement is the main clinical manifestation. At present, hormones and immunosuppressants are still the main means of treatment for SLE. But hormones are a double-edged sword. While suppressing inflammation and reducing disease activity, long-term use of such drugs can lead to serious adverse reactions such as metabolic disorders. The characteristic of traditional Chinese medicine is that long-term administrat...

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Problems solved by technology

However, the Qingfengteng in this formula is a poisonous traditional Chinese medicine in the Great Dictionary of Toxic Chinese Medicine of the People's Republic of China, which increases the potential safety hazard of clinical medication.

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