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Traditional Chinese medicine composition for preventing and treating hand-foot-mouth disease

A hand, foot, and mouth disease and composition technology, which is applied in the field of traditional Chinese medicine compositions for preventing and treating hand, foot, and mouth disease, can solve the problems of lycorine antibody-dependent infection enhancement, and achieve good control effects

Inactive Publication Date: 2015-12-02
陈巧真
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Other drugs for the prevention and treatment of HFMD are in the stage of laboratory research, and there is still a long way to go before clinical application. For example, lycorine inhibits the reproduction of HFMD virus, and virus neutralizing antibodies block HFMD virus infection, thus It has the ability to prevent and treat hand-foot-mouth disease, but lycorine has toxicity and neutralizing antibodies have antibody-dependent infection enhancement. Whether this kind of hand-foot-mouth disease candidate drug can be used as a clinical drug is unknown.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0070] A traditional Chinese medicine composition for preventing and treating hand, foot and mouth disease, comprising the following components by weight:

[0071] Pseudostellaria 10, Scutellaria baicalensis 10, Astragalus 10, Gypsum 20, Jiao Sanxian 10, Betel nut 10, Magnolia officinalis 5, Atractylodes macrocephala 10, Fangfeng 5, Angelica dahurica 12, Arctium 8, Magnolia 3, Luo Han Guo 10, Perilla leaves 6-10, Ginger 30, licorice 5.

[0072] The preparation steps are as follows:

[0073] Weigh the above medicine, grind it to 200 mesh, then heat and dry it with hot air circulation at 50°C for 20 minutes, then pour it into distilled water at 35°C, and keep it soaked for 20 hours. The weight of distilled water is 50 times the total weight of the medicine.

[0074] First heat and boil for 3 minutes, then boil at 90°C for 30 minutes, filter to obtain the medicinal liquid after cooling, precipitate, and take the supernatant, which is the finished product of the traditional Chine...

Embodiment 2

[0076] A traditional Chinese medicine composition for preventing and treating hand, foot and mouth disease, comprising the following components by weight:

[0077] Pseudostellaria 15, Scutellaria baicalensis 20, Astragalus 20, Gypsum 30, Jiao Sanxian 15, Betel nut 12, Magnolia officinalis 15, Atractylodes macrocephala 15, Fangfeng 9, Angelica dahurica 15, Arctium 14, Magnolia 5, Luo Han Guo 20, Perilla leaf 10, Ginger 40, Licorice 10.

[0078] The preparation steps are as follows:

[0079] Weigh the above medicine, grind it to 300 mesh, then heat and dry it with hot air circulation at 60°C for 50 minutes, then pour it into distilled water at 45°C, and keep it soaked for 35 hours. The weight of distilled water is 100 times the total weight of the medicine.

[0080] First heat and boil for 5 minutes, then boil at 95°C for 35 minutes, filter to obtain the medicinal liquid after cooling, precipitate, and take the supernatant, which is the finished product of the traditional Chine...

Embodiment 3

[0082] A traditional Chinese medicine composition for preventing and treating hand, foot and mouth disease, comprising the following components by weight:

[0083] Pseudostellaria 10, Scutellaria baicalensis 10, Astragalus 15, Gypsum 25, Jiao Sanxian 12, Betel nut 10, Magnolia officinalis 9, Atractylodes macrocephala 10, Fangfeng 6, Angelica dahurica 12, Arctium 10, Magnolia 6, Luo Han Guo 15, Perilla leaf 10, Ginger 35, Licorice 8.

[0084] The preparation steps are as follows:

[0085] Weigh the above medicine, grind it to 250 mesh, then heat and dry it with hot air circulation at 55°C for 30 minutes, then pour it into distilled water at 40°C, and keep it soaked for 30 hours. The weight of distilled water is 60 times the total weight of the medicine.

[0086] First heat and boil for 5 minutes, then boil at 90°C for 30 minutes, filter to obtain the medicinal liquid after cooling, precipitate, and take the supernatant, which is the finished product of the traditional Chinese ...

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Abstract

A traditional Chinese medicine composition for preventing and treating the hand-foot-mouth disease is prepared from, by weight, 10-15 parts of radix pseudostellariae, 10-20 parts of scutellaria baicalensis, 10-20 parts of radix astragali, 20-30 parts of gypsum, 10-15 parts of parched malt, parched hawthorn fruit and parched medicated leaven mixtures, 10-12 parts of areca catechu, 5-15 parts of mangnolia officinalis, 10-15 parts of atractylodes macrocephala, 5-9 parts of radix sileris, 12-15 parts of radix angelicae, 8-14 parts of arctium lappa, 3-5 parts of flos magnoliae, 10-20 parts of siraitia grosvenorii, 6-10 parts of perilla leaves, 30-40 parts of fresh ginger and 5-10 parts of liquorice. The traditional Chinese medicine composition adopts reasonable components and can have an excellent prevention effect on symptoms of the hand-foot-mouth disease.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for preventing and treating hand, foot and mouth disease. Background technique [0002] Hand, foot and mouth disease is caused by viruses of the family Picornaviridae and the genus Enterovirus, and has become an important infectious disease that endangers the health of infants and young children and public health safety. HFMD is mainly caused by Enterovirus 71 (Enterovirus71, EV71) and Coxsackievirus A16 (Coxsackievirus A16, CA16). Hand, foot and mouth disease is usually a transient infection. It takes 3-6 days from infection to the appearance of clinical symptoms. Papules and herpes often appear on the hands, feet, and mouth. 3-year-old infants and young children will have serious complications, such as viral meningitis, encephalitis, paralysis similar to polio, and myocarditis, pericarditis, cardiomyopathy, and t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P31/14A61K33/06
Inventor 陈巧真
Owner 陈巧真
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