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Detection method of total-component granule Chinese herbal medicine santalum album based on terahertz spectroscopy technology

A spectral technology and spectral detection technology, which is applied in the detection field of Chinese herbal sandalwood in full-component granules, can solve the problems of large interference factors, low measurement repeatability and correlation, and difficulty in obtaining fingerprint peaks of Chinese medicinal materials, etc., to achieve The effect of avoiding pollution, fast detection speed and low cost

Inactive Publication Date: 2016-01-06
CAPITAL NORMAL UNIVERSITY
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Problems solved by technology

However, the research objects of these terahertz tests are still limited to the original unprocessed Chinese medicinal materials or herbal medicinal materials. This form of medicinal materials has not been purified, so impurity molecules and other interference factors to the spectrum are very large, and the measurement repetition The correlation and correlation are not high, and in the limited range of 2.6THz, it is difficult to obtain the obvious characteristic fingerprint peaks of Chinese herbal medicines experimentally.

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  • Detection method of total-component granule Chinese herbal medicine santalum album based on terahertz spectroscopy technology
  • Detection method of total-component granule Chinese herbal medicine santalum album based on terahertz spectroscopy technology

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Embodiment 1

[0030] The present embodiment provides a method for detecting sandalwood using terahertz time-domain spectroscopy, which includes the following steps:

[0031] 1), sample preparation: the sample used is the full-component traditional Chinese medicine sandalwood granule produced by Beijing Kangrentang Pharmaceutical Co., Ltd., weigh about 60 mg of sandalwood granule with an electronic balance, and then grind it into a fine powder in a mortar. Next, set the shape in the tablet press, increase the pressure to 5 tons, and take 8 minutes to obtain a disc with a diameter of 13 mm, smooth on both sides, and a thickness of less than 0.4 mm.

[0032] 2), sample test: turn on the laser until the output power is stable, calibrate the light collimation in the optical path; turn on the laptop, set the measurement parameters on the program panel of the terahertz spectroscopy system software, and measure after the laser warms up for one hour; Put the prepared empty sample rack into the sampl...

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Abstract

The invention relates to the field of Chinese herbal medicine detection, in particular to a detection method of total-component granule Chinese herbal medicine santalum album based on terahertz spectroscopy technology. The invention aims to provide the method characterizing total-component Chinese herbal medicine granules by means of wide frequency band terahertz spectroscopy technology so as to obtain fingerprint peaks within the wide frequency spectrum, and the characteristics of terahertz fingerprint peaks within the wide frequency spectrum are utilized to distinguish different types of total-component Chinese herbal medicine granules. The method solves the problems of spectrum characterization and variety differentiation in measurement of total-component Chinese herbal medicine granules, reduces chemical reagent assistance, is a pure physical detection method, and has the advantages of simple operation, fast data processing and accurate result.

Description

technical field [0001] The invention relates to the field of detection of traditional Chinese medicinal materials, in particular to a detection method of sandalwood, a Chinese herbal medicine in full-component granules, based on terahertz spectroscopy. Background technique [0002] Chinese medicine extract is a new product of traditional Chinese herbal medicine combined with modern pharmaceutical technology. Establishing effective analysis, identification and identification methods will help Chinese medicine extract to promote the international market of Chinese herbal medicine. At present, traditional Chinese medicine extracts are usually a single compound or a complex mixture system such as full-ingredient extract granules. Traditional Chinese medicine is a complex mixture system. The advantage of traditional Chinese medicine lies in "multi-armed joint operations", that is, compound prescriptions to treat diseases. The theory of yin and yang and five elements is often used...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/3586
Inventor 左剑刘尚建张存林
Owner CAPITAL NORMAL UNIVERSITY