Donkey-hide glue small peptide composition for resisting fatigue

A technology of Ejiao small peptide and composition, applied in the directions of drug combination, peptide, antidote, etc., can solve the problems of large dosage and poor efficacy, and achieve the effects of enhancing immune function, regulating gastric contraction, and promoting hematopoietic function.

Inactive Publication Date: 2016-01-20
ANHUI BIOLOGICAL PEPTIDE IND RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Nowadays, traditional Chinese medicine compound formulas have low ingredients, large doses, and poor efficacy

Method used

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  • Donkey-hide glue small peptide composition for resisting fatigue
  • Donkey-hide glue small peptide composition for resisting fatigue

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] Prescription: Donkey-hide gelatin small peptide 60g Codonopsis astragalus lily total polysaccharide 120g Rhodiola total glycosides 70g Cistanche deserticola phenylethanol glycosides 70g

[0078] Preparation method: Preparation of donkey-hide gelatin small peptide: Take 50kg donkey-hide gelatin, crush it properly, pass through a 60-mesh sieve, add 20 times the amount of water, stew at 60°C, cool to room temperature, adjust the pH to 2.0 with hydrochloric acid, and then add 1 % pepsin, hydrolyzed in a water bath at 42°C for 1.5h, and then inactivated in a water bath at 85°C for 15min. After cooling, adjust the pH to 8 with sodium hydroxide solution, add trypsin with 1% substrate amount, enzymatically hydrolyze in a water bath at 42°C for 2.5 hours, and then inactivate in a water bath at 85°C for 15 minutes. Then keep the inactivated enzymolysis solution in a 40°C water bath, centrifuge, collect the supernatant, adjust the pH to 6.5-7.0, add 1%-3% activated carbon, stir ev...

Embodiment 2

[0084] The active part raw material prepared in Example 1 was used.

[0085] Take 300g donkey-hide gelatin small peptide, 900g codonopsis astragalus lily polysaccharide, 350g salidroside total glycosides, 350g phenylethanol glycosides from cistanche deserticola, add starch to 2600g, and make 10000 capsules.

Embodiment 3

[0087] The active part raw material prepared in Example 1 was used.

[0088] Take 120g donkey-hide gelatin small peptide, 300g Codonopsis astragalus lily polysaccharide, 140g salidroside total glycosides, and 140g phenylethanol glycosides from Cistanche deserticola, add dextrin to a total of 800g, dry-press granules, and obtain.

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PUM

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Abstract

The invention discloses an anti-fatigue traditional Chinese medicine effective component composition as well as a preparation method and application thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition takes effective components extracted from donkey-hide glue, codonopsis pilosula, milkvetch root, lily, root of kirilow rhodiola and all-grass of desertliving cistanche as main components of the medicine, is prepared into appropriate dosage forms, and is relatively good in curative effect of resisting fatigue. Moreover, the anti-fatigue composition disclosed by the invention does not have any toxic or side effects, and does not show effects of mutagenesis and teratogenesis after being taken by animals for a long time. Therefore, the anti-fatigue composition disclosed by the invention is safe and effective, and is suitable for taking for a long time by fatigable people suffering from fast-paced work and overstrain nerves, and high-end people including middle-aged and aged people and the like.

Description

technical field [0001] The present invention relates to a composition of active parts of traditional Chinese medicine with anti-fatigue effect and a preparation method thereof, specifically a composition of effective parts of traditional Chinese medicine extracted from donkey-hide gelatin, Codonopsis pilosula, astragalus, lily, rhodiola rosea and cistanche, and a preparation method thereof. It belongs to the field of traditional Chinese medicine. Background technique [0002] Fatigue is a comprehensive physiological process involving many physiological and biochemical factors, and it is a normal physiological phenomenon that must occur when the human body's mental or physical activities reach a certain stage. It not only marks the temporary decline of the original working ability of the body, but also may be a precursor to the development of the body into an injury state. In 1982, at the Fifth International Sports Biochemical Academic Conference, fatigue was defined as: the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/01A61P39/00C12P21/06C07K1/34C08B37/00A61K36/41A61K36/64A61K31/715
Inventor 柏道鸣凌中鑫
Owner ANHUI BIOLOGICAL PEPTIDE IND RES INST
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