Traditional Chinese medicine for treating chronic colitis and preparation method thereof

A technology for chronic colitis and traditional Chinese medicine, applied in pharmaceutical formulations, medical preparations containing active ingredients, drug combinations, etc., can solve problems such as inability to share or use antibiotics for a long time, affecting the quality of life of patients, and large side effects in the liver, and achieve improvement. Intestinal mucosa pathological changes, promoting ulcer healing and eliminating inflammatory mediators

Inactive Publication Date: 2016-03-09
ZHENGZHOU ZHENGXIAN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among these drugs, sulfasalazine has serious side effects on the liver, and cannot be shared with antibiotics or used for a long time
Surgical treatment is to remove the entire colon, but due to many surgical complications, it seriously affects the quality of life of patients after surgery

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] In the embodiment of the present invention, weigh raw materials: Ophiopogon japonicus 15g, Morinda officinalis 10g, Shengdi 5g, Daqingye 6g, licorice 16g, Yizhi 9g, peach kernel 4g, ebony 12g, Donglingcao 6g, Campanulaceae 3g, Kochia scop 14g of seeds, 4g of eucalyptus leaves.

[0021] The specific steps of preparation include:

[0022] 1) Wash, cut and dry Ophiopogon japonicus, Morinda officinalis, Shengdi, Daqingye, licorice, Yizhi, peach kernel, black plum, Donglingcao, platycodon, Kochia, and Eucalyptus leaves, according to the above weight Weigh, reserve;

[0023] 2) Boil Ophiopogon japonicus, Morinda officinalis, Shengdi, Daqingye, licorice, Yizhi, peach kernel, ebony, and all traditional Chinese medicines in water 7-8 times the total weight, each time for 1-1.5h, filter and combine Concentrate the filtrate into an extract with a specific gravity of 1.0, add ethanol for alcohol precipitation, recover and concentrate the ethanol, and dry at 60-65°C to obtain extr...

Embodiment 2

[0027] In the embodiment of the present invention, raw materials were weighed: Ophiopogon japonicus 22g, Morinda officinalis 14g, Shengdi 9g, Daqingye 12g, licorice 22g, Yizhi 14g, peach kernel 9g, ebony plum 18g, Donglingcao 11g, Campanulaceae 6g, Kochia scop 19g of seeds, 8g of eucalyptus leaves. The preparation steps are consistent with Example 1.

Embodiment 3

[0029] In the embodiment of the present invention, the raw materials are weighed: 17g of Ophiopogon japonicus, 11g of Morinda officinalis, 6g of habitat, 8g of Daqingye, 18g of licorice, 10g of Yizhi, 6g of peach kernel, 14g of ebony plum, 8g of Donglingcao, 4g of Platycodon grandiflorum, and Kochia scoparia 16g of seeds, 5g of eucalyptus leaves. The preparation steps are consistent with Example 1.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine for treating chronic colitis and a preparation method thereof. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 15 to 22 parts of tuber of dwarf lilyturf, 10 to 14 parts of morinda officinalis, 5 to 9 parts of rehmanniae radix, 6 to 12 parts of folium isatidis, 16 to 22 parts of licorice, 9 to 14 parts of alpinia oxyphylla, 4 to 9 parts of peach seed, 12 to 18 parts of dark plum, 6 to 11 parts of rabdosia rubescens, 3 to 6 parts of balloonflower root, 14 to 19 parts of broom cypress fruit, and 4 to 8 parts of leaf of eucalyptus robusta. The preparation method comprises the following steps: washing raw materials, cutting and drying raw materials, adding water into tuber of dwarf lilyturf, morinda officinalis, and the like, decocting tuber of dwarf lilyturf, morinda officinalis, and the like for three times, condensing the decoction, carrying out alcohol precipitation, drying the precipitate to obtain extract (A); adding ethanol into rabdosia rubescens, balloonflower root, and the like, performing reflux, drying to obtain extract (B); merging extract (A) and extract (B), grinding, and mixing. The provided traditional Chinese medicine can quickly relieve the clinical symptoms of ulcerative colitis patients such as diarrhea, pus and blood stool, stomachache, and the like; can prominently improve the pathological change of intestinal mucosa, eliminate the inflammation medium, and promote the healing of ulcer; and achieves a good curative effect. The total effective rate is 96%, and no adverse reaction, side effect, or toxic effect has been found.

Description

technical field [0001] The invention relates, in particular, to a traditional Chinese medicine for treating chronic colitis and a preparation method thereof. Background technique [0002] Chronic colitis is a chronic inflammatory disease of unknown etiology characterized by the mucosa and submucosa of the large intestine (mainly the rectum and colon). Ulcerative colitis is a chronic nonspecific inflammatory disease of the colon and rectum whose etiology is not yet clear, and the lesions are limited to the mucosa and submucosa of the large intestine. The lesions are mostly located in the sigmoid colon and rectum, and can also extend to the descending colon, or even the entire colon. The course of the disease is long and often recurrent. The disease is seen at any age, but it is most common in 20-30 years old. The cause of ulcerative colitis is still unknown. [0003] The current traditional treatment is basically taking drugs and injections, as well as surgery to remove t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61P1/00
CPCA61K36/9062A61K36/185A61K36/195A61K36/315A61K36/346A61K36/484A61K36/53A61K36/61A61K36/704A61K36/736A61K36/746A61K36/804A61K36/855A61K36/8968A61K2236/33A61K2236/331A61K2236/39A61K2236/51A61K2236/53
Inventor 顾晓荣
Owner ZHENGZHOU ZHENGXIAN PHARMA CO LTD
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