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Pharmaceutical composition for treating beriberi

A composition and drug technology, applied in the direction of drug combination, drug delivery, active ingredients of heterocyclic compounds, etc., to achieve better effects, reasonable compatibility, and simple preparation methods

Pending Publication Date: 2016-05-18
ZHEJIANG AEGIS BIOLOGICAL SCI & TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0027] At present, the application of combining lysozyme and osthole for the prevention and treatment of beriberi has not been reported

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Embodiment 1, prepare the ointment containing osthole

[0043] Weigh 10 parts by weight of osthole, 50 parts by weight of sodium carboxymethyl cellulose, 10 parts by weight of zinc oxide and 1 part by weight of disodium ethylenediamine tetraacetate and disperse them in 500 parts by weight of purified water, stir evenly Obtain the water phase; then weigh 50 parts by weight of vaseline, put 10 parts by weight of Tween 80 in another container, and mix to obtain the oil phase; heat the water phase and the oil phase respectively, mix them, homogenize for 10 minutes, and cool down Make ointment A1 containing osthole.

Embodiment 2

[0044] Embodiment 2, prepare the ointment containing lysozyme

[0045] Weigh 10 parts by weight of lysozyme, 50 parts by weight of sodium carboxymethylcellulose, 10 parts by weight of zinc oxide and 1 part by weight of disodium ethylenediamine tetraacetate and disperse them in 500 parts by weight of purified water, and stir to obtain water phase; then weigh 50 parts by weight of vaseline, put 10 parts by weight of Tween 80 in another container, and mix to obtain an oil phase; heat the water phase and the oil phase respectively, mix them, homogenize for 10 minutes, and prepare into ointment A2 containing lysozyme.

Embodiment 3

[0046] Embodiment 3, prepare the ointment containing lysozyme and osthole (1:1)

[0047] Weigh 5 parts by weight of lysozyme, 5 parts by weight of osthole, 50 parts by weight of sodium carboxymethylcellulose, 10 parts by weight of zinc oxide and 1 part by weight of disodium edetate dispersed in 500 parts by weight 50 parts by weight of Vaseline, and 10 parts by weight of Tween 80 in another container, mixed to obtain an oil phase; the water phase and the oil phase were heated and mixed respectively, Homogenize for 10 minutes, and make ointment A3 containing lysozyme and osthole (1:1 by weight) after cooling down.

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PUM

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Abstract

The invention relates to a pharmaceutical composition for treating beriberi. The weight ratio of the active ingredient lysozyme to the active ingredient osthole is (1:10)-(10:1). Compared with ordinary western medicine preparations, the lysozyme preparation has the advantages that the preparing method is simple, compatibility of medicines is high, and the two active ingredients have their own functions and can also generate synergistic interaction so as to treat beriberi remarkably. Lysozyme and osthole both have natural sources and are safe, free of toxin and free of side effect. Due to the fact that no western medicine antibacterial agent is contained in the pharmaceutical composition, the pharmaceutical composition has no drug resistance.

Description

technical field [0001] The invention relates to the field of pharmacy, in particular to a medicine for treating beriberi. Background technique [0002] Athlete's foot is also called "tinea pedis" in medicine, commonly known as "Hong Kong's foot", which is a fungal infection of the foot. It manifests as itching, erythema, papules, peeling, or blisters between the toes or on the soles of the feet, which can erode and ooze in severe cases. If it is not controlled in time, it will spread to other parts, causing tinea corporis, jock itch or "onychomycosis". In medicine, beriberi is usually divided into three types: erosive, vesicular, and keratotic beriberi. The erosive type occurs between the third and fourth, fourth and fifth toes. At the beginning, the toes are wet, impregnated and whitish or have small blisters. After drying and desquamation, peeling off the dander becomes a moist, flushed, erosive surface, which is extremely itchy and prone to secondary infection. The ve...

Claims

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Application Information

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IPC IPC(8): A61K38/47A61P17/00A61P31/10A61K31/37
CPCA61K38/47A61K9/0014A61K9/06A61K31/37A61K47/02A61K47/06A61K47/183A61K47/38C12Y302/01017
Inventor 潘宏涛卢亚萍
Owner ZHEJIANG AEGIS BIOLOGICAL SCI & TECH CO LTD
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