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Anti-adhesion patch having internal drainage function

An anti-adhesion and internal drainage technology, used in wound drainage devices, medical science, prostheses, etc., can solve the problems of cumbersome preparation process, easy delamination, high cost, etc., and achieve excellent ingrowth performance, reduce adhesion, and compliance. Good results

Active Publication Date: 2016-05-25
TRANSEASY MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation of this product has gone through many chemical reactions, which is relatively complicated and adds a large cost to the production process.
[0007] The above products may have problems such as cumbersome preparation process, many chemical reactions, easy delamination, easy to cause serous swelling, affect the healing of tissue and repair materials, and have controversial anti-adhesion effects

Method used

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  • Anti-adhesion patch having internal drainage function
  • Anti-adhesion patch having internal drainage function
  • Anti-adhesion patch having internal drainage function

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] The manufacturing process of the anti-adhesion patch with internal drainage function according to the present invention will be described in detail below with a specific example. Described manufacturing process specifically comprises the following steps:

[0041] 1. Solution preparation

[0042] 1.1 Materials: PLCL pellets, acetone.

[0043] 1.2 Apparatus: 1000ml volumetric flask, 250ml measuring cylinder, 250ml Erlenmeyer flask.

[0044] 1.3 Environment: Class 100,000 clean workshop

[0045] 1.4 Equipment dry heat sterilization, 165 ℃, 2 hours. Rinse with acetone before use.

[0046] 1.5 Take the PLCL pellets, open it at room temperature, pour it into a 1000ml volumetric flask, add acetone to make the volume to 1000ml, cover the bottle tightly and place it at 40°C to dissolve for 48-72 hours, shake and shake during the period, and use it as a film-making PLCL solution for later use (PLCL concentration: 0.1 g / ml).

[0047] 1.6 Take 100ml of film-making PLCL soluti...

Embodiment 2

[0108] 1. Solution preparation

[0109] 1.1 Materials: PLCL, MPEG2000-PLLA6000, acetone.

[0110] 1.2 Apparatus: 1000ml volumetric flask, 250ml measuring cylinder, 250ml Erlenmeyer flask.

[0111] 1.3 Environment: Class 100,000 clean workshop

[0112] 1.4 Equipment dry heat sterilization, 165 ℃, 2 hours. Rinse with acetone before use.

[0113] 1.5 Prepare 10 grams of MPEG2000-PLLA6000, open it at room temperature, pour it into a 1000ml volumetric flask, add acetone, cover the bottle tightly and place it at 40°C to dissolve, then add 90 grams of PLCL, stir to dissolve completely, and add acetone to make it to 1000mL , to be used as a film-making mixed solution (the mass ratios of PLCL and MPEG2000-PLLA6000 are 9:1, 7:3, and 1:1, respectively).

[0114] 1.6 Add 100ml of film-forming PLCL solution into a 250ml Erlenmeyer flask, then add 100ml of acetone, cap the bottle tightly and shake well, and use it as a coating mixed solution for later use.

[0115] 2. Fusion

[0116] ...

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Abstract

The invention relates to an anti-adhesion patch having an internal drainage function, belonging to the technical field of medical consumables. The anti-adhesion patch having the internal drainage function comprises a polypropylene mesh and a polylactide-caprolactone membrane layer, wherein the surface of the polypropylene mesh is dipcoated with a polylactide-caprolactone coating, and the polylactide-caprolactone membrane layer is laminated on the polypropylene mesh; drainage holes are formed in the polylactide-caprolactone membrane layer. The integrity of the polylactide-caprolactone membrane layer of the anti-adhesion patch can be maintained for 30 days or more in the human body, and the complete absorption time of the polylactide-caprolactone membrane layer is 90-120 days. Compared with hot-pressing or molding by casting, the anti-adhesion patch enables polypropylene and the anti-adhesion membrane to be completely nested with each other, and microscopic examination proves no obvious boundary surface exists, so that the phenomenon of stratification does not occur. The anti-adhesion patch is suitable for itra-abdominal herniorrhaphy of abdominal hernia and abdominal wall defect as well as itra-abdominal herniorrhaphy of laparoscopic inguinal hernia.

Description

technical field [0001] The invention relates to the technical field of medical consumables, and more specifically, the invention relates to an anti-adhesion patch with internal drainage function. Background technique [0002] A hernia is a fascial defect in a structure, such as the abdominal wall, through which an organ or part of an organ, tissue or part of a tissue can protrude. Usually it involves a weakening, bulging or actual tearing of the fascia that normally structurally contains the organ or tissue. There are many types of hernias. For example, when in the lower abdominal region, hernias often contain intra-abdominal contents, such as bowel or other tissue, that enter or pass through a defect in the abdominal wall. Mesh mesh is widely used in hernia repair. Currently commonly used hernia repair sheets are polyester mesh (such as Dacron, Mersilene) and polypropylene mesh (such as Marlex, Prolene, etc.). However, pure non-degradable mesh cannot be used for intrape...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/00A61M27/00A61L31/04A61L31/14
CPCA61F2/0063A61L31/048A61L31/14A61M27/002C08L23/12
Inventor 何建庆孙杰陈凡乔红英丁玲翠
Owner TRANSEASY MEDICAL TECH
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