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Traditional Chinese medicine for treating alcohol-induced osteonecrosis of femoral head and preparation method of traditional Chinese medicine

A femoral head necrosis, alcohol-based technology, applied in the direction of medical formula, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems of avascular necrosis of the femoral head and achieve no adverse reactions, Improve the cure rate and total effective rate, the effect of no toxic side effects

Inactive Publication Date: 2016-06-01
庄蕾
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

How long and how much alcohol you drink every day can lead to avascular necrosis of the femoral head. At present, there is no definite clinical data at home and abroad

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0044] The present invention also provides the preparation method of above-mentioned Chinese medicine, and the dosage form of described Chinese medicine is oral liquid, and its preparation method comprises the following steps:

[0045] The first step is to mix Dongli Ma, Shrimp Raft Grass, Shiqingcai, Geman, Kanmai Niang, Shanxiaoju, Rolling Mountain Worm and Snake Hanshi, and add 3 to 5 times the amount of alcohol concentration to 55 %-65% ethanol reflux extraction 2-4 times, 2-3 hours each time, filter, combine the filtrates, recover ethanol, concentrate to a paste with a relative density of 1.30-1.32 at 70°C, and set aside;

[0046] The second step is to mix the remaining raw medicinal materials in proportion, add 3 to 5 times the amount of water relative to the mixture, boil for 2 to 4 hours, filter, and concentrate to a paste with a relative density of 1.27 to 1.29 at 70°C;

[0047] The third step is to mix the paste obtained in the first step and the second step, and dry...

Embodiment 1

[0055] Embodiment 1: oral liquid

[0056] Take 150g Donglima, 140g Shrimp Grass, 180g Shiqingcai, 160g Pueraria, 160g Kanmai Niang, 250g Shanxiaoju, 120g Rolling Mountain Worm, 200g Shehanshi, 140g Scallion, 280g Desmodium, 220g Fir Fruit, 150g Yahuazi, 140g broken rice firewood, 200g chicken gizzard grass, 160g prickly water grass and 290g water golden phoenix;

[0057] Prepare as follows:

[0058] The first step is to mix Dongli Ma, Shrimp Raft Grass, Shiqingcai, Geman, Kanmai Niang, Shanxiaoju, Rolling Mountain Worm and Shehanshi, and add ethanol with an alcohol concentration of 65% relative to the mixture, which is 5 times the amount Reflux extraction 3 times, 2 hours each time, filter, combine the filtrates, recover ethanol, concentrate to a paste with a relative density of 1.31 at 70°C, and set aside;

[0059] In the second step, mix the remaining raw medicinal materials in proportion, add 3 times the amount of water relative to the mixture, boil for 2 hours, filter, a...

Embodiment 2

[0064] Embodiment 2: Granules

[0065] Take 180g of Dongli Ma, 100g of Shrimp Grass, 220g of Shiqingcai, 140g of Geman, 200g of Mai Niang, 220g of Shanxiaoju, 150g of Rolling Mountain Worm, 180g of She Hanshi, 160g of Scallion, 250g of Desmodium, 240g of Fir Fruit, 120g Yahuazi, 170g broken rice firewood, 160g chicken gizzard grass, 190g water grass and 260g water golden phoenix;

[0066] Prepare as follows:

[0067]Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 6 times that of the mixture and 90% ethanol, heat to boiling and reflux for 3 hours, filter, and use the percolation method at a rate of 2ml per minute. Percolation, collect the percolation liquid, then concentrate under reduced pressure at 0.07Mpa to a paste with a relative density of 1.07 at 60°C, spray dry, the air inlet temperature of the spray dryer is 175°C, and the air outlet temperature is 85°C, then Crushed into powder, made into dry cream ...

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Abstract

The invention provides a traditional Chinese medicine for treating alcohol-induced osteonecrosis of femoral head and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine comprises the following raw herbs: edible debregeasia root and leaf, all-grass of capitatestigma willowweed, herb of Chinese chlamydoboea, pueraria stem, Alopecurus aequalis Sobol., root of citrusleaf glycosmis, glomeris, limonite, longstamen onion bulb, longhairy antenoron herb, delavay fir seed, Pittosporum illicioides Makino, small-leaved desmodium, wight parnassia herb, all-grass of Arcuaate iolet and flower or root of Lightyellow snapweed. The traditional Chinese medicine and the preparation method thereof have the following benefits: the traditional Chinese medicine can be used together with the western medicine interventional therapy to treat alcohol-induced osteonecrosis of a femoral head, the cure rate and the total effective rate are effectively improved, and toxic and side effects, as well as adverse effects, are prevented.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating alcoholic femoral head necrosis and a preparation method thereof. Background technique [0002] Alcoholic femoral head necrosis is a kind of femoral head necrosis caused by excessive drinking. Among alcoholic patients, the incidence of femoral head necrosis was significantly higher than that of the general population. Significantly more men than women. Alcoholism (excessive drinking) intake is a cause of osteonecrosis of the femoral head has been proven, that is to say whether the occurrence of osteonecrosis of the femoral head is related to the amount of alcohol consumed and the number of years of drinking. Men who have been drinking for more than 10 years are more likely to suffer from femoral head necrosis, which is 50% higher than normal. [0003] Alcoholic femoral head necros...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P19/08A61K33/26A61K35/64
CPCA61K36/185A61K9/0095A61K9/1652A61K33/26A61K35/63A61K36/15A61K36/48A61K36/53A61K36/75A61K36/8962A61K47/26A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 庄蕾王发芬
Owner 庄蕾
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