a blood culture bottle

A blood culture and culture bottle technology, applied in the field of blood culture bottles, can solve the problems of unacceptable fluorescent substances and product failure, and achieve the effects of reducing the probability of false negative or false positive, not easy to quench, and stable fluorescent substances
CN105647785BActive Publication Date: 2018-10-30JIANGSU ZHONGSHENG MEDICAL DIAGNOSTIC REAGENT
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
JIANGSU ZHONGSHENG MEDICAL DIAGNOSTIC REAGENT
Publication Date
2018-10-30

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Abstract

The invention provides a blood culture bottle. The blood culture bottle comprises a culture bottle body, a sensing layer, adsorbent resin and a culture medium, wherein the sensing layer comprises a fluorescent substance and a substrate; the fluorescent substance comprises an rhodamine pH fluorescent probe, namely an Rh-pH fluorescent probe containing a glutamic acid structure; the structural general formula of the Rh-pH fluorescent probe is shown as I. The blood culture bottle provided by the invention has the following technical effects that firstly, the fluorescent substance in the blood culture bottle is more stable and is not easy to quench, so that the probability that false negative or false positive appears in the diagnostic process is remarkably reduced; in addition, the fluorescent substance can endure high temperature of 121DEG C or over 121DEG C; a product can be subjected to autoclave sterilization at last; secondly, compared with a foreign imported product, the blood culture bottle disclosed by the invention is higher in sensitivity; results of the same positive specimen can be detected in a shorter time.
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Description

technical field

[0001] The invention relates to a blood culture bottle and belongs to the technical field of medical detection. Background technique

[0002] Since the 1990s, my country's automatic blood culture system has long been monopolized by the automatic blood culture systems of BD Company of the United States and Mérieux Company of France. The cost of expenses has brought a heavy burden. In recent years, with the development of the medical device industry, products that can replace Mérieux blood culture bottles have emerged in China, but there are very few products that can replace BD fluorescent blood culture bottles and meet the quality standards.

[0003] The existing similar products in foreign countries are produced in a completely sterile environment during the manufacturing process. Since fluorescent substances cannot withstand high temperature final sterilization, a little environmental change or operational error during the production process will cause prod...

Claims

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