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Antiviral oral liquid for animals and preparation method thereof

An antiviral oral liquid, a technology of traditional Chinese medicine components, applied in antiviral agents, medical preparations containing active ingredients, pharmaceutical formulations, etc., can solve problems such as no veterinary drugs, achieve simple formula, reduce dosage and feed Cost, efficacy of treatment and prevention improvement

Inactive Publication Date: 2016-06-15
济南亿民动物药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, in this technical field, there is no effective veterinary drug

Method used

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  • Antiviral oral liquid for animals and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] This embodiment provides a traditional Chinese medicine extract of veterinary antiviral oral liquid:

[0027] (1) Weigh Chinese herbal medicines: 10g of Radix Radix, 5g of Honeysuckle, 5g of Forsythia, 5g of Gardenia, 10g of Astragalus, 8g of Echinacea, 5g of Dandelion, 20g of Gypsum, 5g of Perilla Leaf, and 5g of Pulsatilla.

[0028] (2) After pulverizing the Chinese herbal medicine, add 8 times of water to decoct for 3 times, 2 hours each time, collect the filtrate three times, combine and concentrate to 1g (original medicinal material) / mL, and obtain the unfermented Chinese medicine extract.

Embodiment 2

[0030] The present embodiment provides a kind of veterinary antiviral oral liquid:

[0031] (1) Weigh 10g of isatidis root, 5g of honeysuckle, 5g of forsythia, 5g of gardenia, 10g of astragalus, 5g of dandelion, 20g of raw gypsum, 5g of perilla leaf, and 5g of pulsatilla.

[0032] (2) After pulverizing the Chinese medicinal materials, add 8 times of water to decoct 3 times, 2 hours each time, collect the filtrate three times, combine and concentrate to 1g (original medicinal materials) / mL;

[0033] (3) The traditional Chinese medicine extract was sterilized at 121°C for 20 minutes;

[0034] (4) Insert the frozen Lactobacillus acidophilus, Lactobacillus plantarum and Candida utilis strains after the seed medium is sterilized, and cultivate at 37° C. for 18 hours to obtain the seed solution;

[0035] (5) Add the cultured seed solution to the sterilized extract at an inoculum size of 5%, cultivate at a constant temperature of 37°C for 48 hours, and the pH drops to 3.85. After th...

Embodiment 3

[0037] This embodiment provides another veterinary antiviral oral liquid:

[0038] (1) Weigh 8g isatidis, 5g honeysuckle, 5g gardenia, 10g astragalus, 5g echinacea, 5g dandelion, and 5g pulsatilla.

[0039] (2) After pulverizing the Chinese medicinal materials, add 6 times of water to decoct 3 times, 2 hours each time, collect the filtrate three times, combine and concentrate to 1g (original medicinal materials) / mL;

[0040] (3) The traditional Chinese medicine extract was sterilized at 121°C for 20 minutes;

[0041] (4) After the seed medium is sterilized, insert frozen Lactobacillus acidophilus, Lactobacillus plantarum, Enterococcus faecalis, Enterococcus faecium, Saccharomyces cerevisiae and Candida utilis strains, and cultivate them at 37°C for 18 hours to obtain seeds liquid;

[0042] (5) Add the cultured seed solution to the sterilized Chinese medicine extract at an inoculum amount of 5%, cultivate at a constant temperature of 37°C for 24 hours, the pH drops to 3.95, f...

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Abstract

The invention relates to the technical field of veterinary drugs, particularly, the technical field of preparing antiviral veterinary medicines by utilizing symbiosis fermentation of multiple strains of probiotics, and in particular to antiviral oral liquid for animals and a preparation method of the antiviral oral liquid. The antiviral oral liquid for animals is prepared from traditional Chinese medicine components, lactic acid bacteria and yeast. According to the antiviral oral liquid disclosed by the invention, traditional veterinary herbal medicines and micro ecology are organically combined, the functions of reducing toxicity and enhancing the efficacy of the veterinary herbal medicines are realized, the unification of prevention, treatment and conditioning is realized, the dosage and the feeding cost are effectively reduced, and a new safe medicine is provided for green cultivation.

Description

technical field [0001] The invention relates to the technical field of veterinary medicine, in particular to the technical field of preparing antiviral veterinary medicine by symbiotic fermentation of multiple strains of probiotic bacteria, in particular to a veterinary antiviral oral liquid and a preparation method thereof. Background technique [0002] Viruses are important pathogens that seriously endanger human life and the safety of animal husbandry, such as avian influenza virus, which has brought great harm to my country's economic security and social stability. Western antiviral drugs are basically ineffective when taken orally, while traditional Chinese veterinary drugs have a better effect in virus prevention and control. However, traditional Chinese veterinary medicine has problems such as large dosage, slow absorption, slow effect, high cost, and low bioavailability, which seriously restrict the development and application of Chinese veterinary medicine. [0003...

Claims

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Application Information

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IPC IPC(8): A61K36/744A61K9/08A61P31/12A61P1/00A61P37/04A61K35/744A61K35/747A61K33/06
CPCA61K36/744A61K9/0053A61K9/08A61K33/06A61K35/744A61K35/747A61K36/06A61K36/195A61K36/28A61K36/288A61K36/315A61K36/355A61K36/481A61K36/535A61K36/634A61K36/71A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 王林周玉武王涛王莹冉蓉杨建朋杨艳艳张敏
Owner 济南亿民动物药业有限公司
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