Non-irritant contraceptive gel with function of inhibiting bacteria and preparation method thereof

Abstract

The invention provides a non-irritant contraceptive gel with a function of inhibiting bacteria and a preparation method thereof, relates to contraceptive gel and a preparation method thereof, and aims to improve the nonoxinol spermicidal effect and solve the problem of side effect caused when existing nonoxinol is used for killing sperms. The gel is prepared from the following main components: chlorhexidine acetate, aloe gel, nonoxinol, pomegranate powder, turmeric extract and platycodin D. The method comprises the following steps of: 1, adding water into Carbomer to swell to obtain a Carbomer solution; regulating the pH value to obtain gel; 2, dissolving aloe gel with water to obtain aloe gel solution; and 3, adding ethanol and tween 80 into chlorhexidine acetate, uniformly stirring to obtain a mixed solution, adding pure water, uniformly stirring, adding into gel and nonoxinol to obtain mixture; and 4, adding pomegranate powder, turmeric extract and platycodin D, and uniformly mixing to obtain a contraceptive gel. The contraceptive gel has a good sperm killing effect, does not have side effect if being used for a long time, and is used in the field of contraceptive medicines.

Description

technical field [0001] The invention relates to a contraceptive gel and a preparation method thereof. Background technique [0002] Population explosion has become a major global problem. Worldwide, more than 200 million pregnancies occur each year, 50% of which are unintended. my country is a country with a large population, and family planning is our basic national policy. The research and development of contraceptives has always attracted much attention. Spermicides are contraceptive drugs that are used in the vagina before sexual intercourse to prevent pregnancy. Spermicides are very effective when used in conjunction with other barrier contraceptive methods. How to improve the spermicidal efficiency and effect of drugs and prevent unintended pregnancy caused by the use of drugs is a hot spot in current research. [0003] The currently widely used spermicide is nonoxynol-9 (nonoxynol-9, N-9), but long-term use of nonoxynol will destroy the normal vaginal flora, cause ...

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is in order to improve nonoxynol spermicidal effect, and solve the problem of the side effect that brings during existing nonoxynol spermicidal, provide a kind of nonirritant contraceptive gel with antibacterial function and its Preparation