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Preparation for treating porcine bacterial respiratory diseases and preparation method thereof

A bacterial and respiratory technology, applied in the field of veterinary drug long-acting compound cefquinome sulfate injection and its preparation, can solve the problems of weight loss of sick animals, difficult to control the disease and cure, economic loss of farmers and other problems, and achieve the effect of medicine The effect of prolonging the time, enhancing the bactericidal effect, and improving the phagocytosis ability

Active Publication Date: 2016-08-31
QILU ANIMAL HEALTH PROD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For a long time, general drugs or unilateral drugs are difficult to control and cure the disease, causing serious economic losses to farmers
In addition, frequent injections are a labor-intensive job for veterinarians, which will cause greater stress to animals, especially those with poor compliance, which may lead to weight loss of sick animals

Method used

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  • Preparation for treating porcine bacterial respiratory diseases and preparation method thereof
  • Preparation for treating porcine bacterial respiratory diseases and preparation method thereof
  • Preparation for treating porcine bacterial respiratory diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] A kind of injection that is used for the treatment of porcine bacterial respiratory disease, every hectoliter composition is as follows:

[0050] Name of raw material

Dosage

cefquinome sulfate

7.5kg (calculated as cefquinome)

Panax notoginseng saponins

5kg

Aluminum stearate

3kg

Span 80

0.1kg

Soybean oil

Set volume to 100L

[0051] The above-mentioned preparation method for the injection of porcine bacterial respiratory disease, comprises the steps:

[0052] (i) mixing soybean oil and aluminum stearate in proportion, stirring and heating to 130° C., dissolving the suspending agent in soybean oil to obtain a gel;

[0053] (ii) Cool the gel prepared in step (i) to 40°C, add Span 80, stir evenly, then add cefquinome sulfate with a particle size of 10-20 μm and Panax notoginseng with a particle size of 10-20 μm Saponin, stir evenly, make initial mixture;

[0054] (iii) Grinding the initial mixed sol...

Embodiment 2

[0056] A kind of injection that is used for the treatment of porcine bacterial respiratory disease, every hectoliter composition is as follows:

[0057] Name of raw material

[0058] The preparation method is the same as in Example 1.

Embodiment example 3

[0060] A kind of injection that is used for the treatment of porcine bacterial respiratory disease, every hectoliter composition is as follows:

[0061] Name of raw material

[0062] The preparation method is the same as in Example 1.

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Abstract

The invention relates to a preparation for treating porcine bacterial respiratory diseases and a preparation method thereof. The medicinal composition of the preparation comprises cefquinome sulfate and panax notoginseng saponins. The invention further relates to an injection solution for treating porcine bacterial respiratory diseases. The injection solution is prepared from cefquinome sulfate, panax notoginseng saponins, a suspending agent, a dispersing agent, and injection oil for fixing the volume, wherein the cefquinome sulfate is measured by cefquinome. Cefquinome sulfate and panax notoginseng saponins in a reasonable proportion are firstly used for preparing the preparation for treating porcine bacterial respiratory diseases, wherein the panax notoginseng saponins can be used for improving the phagocytic ability of alveolar macrophages, enhancing the sterilization efficacy of cefquinome sulfate, achieving the anti-fibrosis effect, inhibiting pulmonary fibrous exudation in the porcine bacterial respiratory diseases and effectively relieving the symptom of dyspnea in time.

Description

technical field [0001] The invention relates to a preparation for treating porcine bacterial respiratory diseases and a preparation method thereof, in particular to a preparation for preventing porcine respiratory diseases caused by Actinomyces pleuropneumoniae, Haemophilus parasuis and Pasteurella multocida. A long-acting compound cefquinome sulfate injection for diseases and a preparation method thereof belong to the technical field of veterinary drugs. Background technique [0002] At present, my country's large-scale pig farming industry has reached a new level. But the following pig disease is increasingly serious to the harm of large-scale pig production, especially the respiratory disease of pig is more prominent. Porcine respiratory disease is one of the most important threats in the swine industry, from sows, suckling piglets, weaned piglets to finishing pigs, there are respiratory disease problems in all stages. Respiratory diseases in swine can lead to increased...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K9/10A61K31/546A61P31/04A61P11/00
CPCA61K9/0019A61K9/10A61K31/546A61K36/258A61K47/44A61K2300/00
Inventor 朱祈明王海挺张金爱张如如黄娟刘金华王金美王甜孔梅吴连勇
Owner QILU ANIMAL HEALTH PROD
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