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A technology of hemorrhoid tablets and Angelica dahurica, which is applied in the field of preparation of hemorrhoid tablets, can solve the problems of unstable granule properties, difficulty in tableting and coating, and incomplete extraction, and achieve uniform granulation, shorten heating extraction time, and reduce high-temperature damage Effect
Active Publication Date: 2018-11-02
GUANGXI YULAN PHARMA CO LTD
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Problems solved by technology
[0003] There are certain deficiencies in the above-mentioned preparation method, such as the main components of rhubarb, a Chinese medicinal material, in hemorrhoid tablets, which are emodin and chrysophanol, and their content is an important index for drug measurement; If the heating time is too long, the content will be reduced, and if the heating time is too short, the extraction will not be complete. The extraction method of rhubarb in the Chinese Pharmacopoeia is: add water to decoct twice, the first time 10 times the amount of water, the second 9 times the amount of water for the second time, due to the large amount of water added and the long heating time, the extraction rate of emodin and chrysophanol in the crude drug rhubarb is usually only about 30%
[0004] In addition, in the preparation method of Pharmacopoeia, Angelica dahurica powder and thick paste are mixed and granulated and dried. Due to the large amount of thick paste, the drying time is long, and the granule properties are unstable, resulting in hard tablets and uneven colors. Clothes Bring Difficulty
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Embodiment 1
[0015] Extract according to the Chinese Pharmacopoeia, put 30 kg of rhubarb into a 500L multifunctional extraction tank, add 300 kg of water for the first time, heat to boiling, extract for one hour, and collect the extract; add 270 kg of water for the second time, heat to boiling , extracted for one hour, combined the two extracts, concentrated and dried to obtain 13.4 kg of dry paste.
Embodiment 2
[0017] Put 50 kg of Zhongda medicinal material yellow into a 500L multi-functional extraction tank, add 350 kg of water for the first time, heat to boiling, keep the temperature at 96±2°C, extract for one hour, and collect the extract; add 300 kg of water for the second time, Heat to boiling, keep the temperature at 96±2°C, extract for one hour, combine the two extracts, concentrate and dry to obtain 17.8 kg of dry paste.
Embodiment 3
[0019] Put 50 kg of Zhongda medicinal material yellow into a 500L multi-functional extraction tank, add 400 kg of water for the first time, heat to boiling, keep the temperature at 96±2°C, extract for one hour, and collect the extract; add 250 kg of water for the second time, Heat to boiling, keep the temperature at 96±2°C, extract for one hour, combine the two extracts, concentrate and dry to obtain 17.2 kg of dry paste.
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Abstract
The invention discloses a preparation method of a haemorrhoids tablet, belongs to the technical field of preparation of traditional Chinese medicines and aims at providing a novel method with high extraction efficiency and good medicinal effect of a product for preparing the haemorrhoids tablet. The preparation method is characterized by comprising the following steps of crushing part of radix angelicae dahuricae into fine powder; decocting residual radix angelicae dahuricae, fructus tribuli and leatherleaf mahonia stem and extracting; decocting and extracting radix et rhizoma rhei; concentrating an extracting solution; mixing thick paste with the radix angelicae dahuricae powder and biliary powder from pig; granulating, drying and mixing a mixture with borneol; adding an accessory and then performing tabletting, wherein extracting conditions of the radix et rhizoma rhei are that 7 to 8 times of water is added for the first time, 5 to 6 times of water is added for the second time, after boiling, the temperature is kept at at 96+ / -2DEG C, and extracting is performed for one hour each time. The preparation method disclosed by the invention is used for preparing the haemorrhoids tablet in Chinese pharmacopoeia.
Description
technical field [0001] The present invention relates to a kind of preparation method of traditional Chinese medicine, more specifically, it relates to a kind of preparation method of hemorrhoid tablet. Background technique [0002] In the Chinese Pharmacopoeia, the prescription of Hemorrhoids Tablets is: 323g rhubarb, 323g Tribulus terrestris, 645g Gongluomu, 323g Angelica dahurica, 16g borneol, 4g pig gall powder; preparation method: take 162g of Angelica dahurica and crush it into fine powder for the above six flavors, and the remaining Angelica dahurica and Tribulus terrestris, Add water to decoct Gonglaomu twice, each time for two hours, filter, and combine the filtrate; add rhubarb to decoct twice, each time for one hour, filter, and combine the filtrate; Mix Angelica dahurica powder and pig gall powder, granulate, dry, grind borneol finely, mix with proper amount of starch, grind finely again, mix with the above granules, add proper amount of starch and talcum powder, ...
Claims
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