37results about How to "Increase the rate of submission" patented technology

The invention discloses a method for preparing a notoginseng triterpene. The notoginseng triterpene is obtained from the caudex or axial root or rootlet or leaf of notoginseng by ultrasonic oscillation extraction, macroporous adsorptive resin passing or water saturated n-butyl alcohol extraction and enrichment, reverse preparation type highly effective liquid chromatographic system purification. The purity of the main active site notoginseng triterpene amounts to 98% above. The notoginseng triterpene has a good action for prevention and treatment of cardiovascular and cerebrovascular diseases.

The invention relates to a new preparation technology for notoginseng danshen root buccal tablet, comprising the following steps: a danshen root tablet and a notoginseng coarse powder are processed by infiltration, water extraction, extractant mergence, concentration and drying, and a dry extract is obtained; after adding an accessories, granulating and tableting, a primary tablet is prepared or a film-coated tablet is prepared by coating a film; the preparation technology is characterized in that after the step of extractant mergence, the extractant is thermally insulated in 70-100 DEG C for 8-36 hours. The new preparation technology has the advantages of greatly increasing the extraction rate of danshen root in notoginseng danshen root buccal tablet, saving medicinal materials, reducing dosage and enhancing therapeutic effect.

The disclosed preparation method for Zn-metalloprotein comprises: cleaning and crushing material for homogenate; filtering, vacuum distilling in kettle of 35-60Deg for extraction; condensing, froze separating at -90~-10Deg, and vacuum drying. This invention has high extraction and purification rate with short period and simple process.

A method for extracting alginic acid belongs to the technical field of marine organism extraction. The method comprises the following steps: (1) enzymatic hydrolysis pretreatment of sargassum: adding water into an openmouthed reactor with a stirring device, adding 4-6 g/L of papain with stirring, after papain is fully dissolved, adding 100-300 g/L of sargassum powder, heating to 50-60 DEG C, keeping the temperature for performing enzymatic hydrolysis for 1-4 h, then stopping stirring; pouring out sargassum subjected to enzymatic hydrolysis, filtering, washing with water to obtained sargassum subjected to enzymatic hydrolysis pretreatment; and (2) extracting alginic acid from the sargassum subjected to enzymatic hydrolysis pretreatment by employing a conventional technology. The method provided by the invention helps to improve the extraction yield of alginic acid, reduce resource consumption and reduce production cost. By utilizing papain to perform enzymatic hydrolysis pretreatment on the raw material sargassum and then employing the conventional technology to extract alginic acid, the extraction yield of alginic acid is substantially improved and reaches 90% or more.

Disclosed is a pharmaceutical composition for treating cardiovascular and cerebrovascular diseases, which is prepared fromacanthopanax root extract, gen-seng extract and medicinal adjuvant for water-soluble injection, and has the functions of benefiting vital energy, promoting blood circulation. The invention also discloses the process for preparing the pharmaceutical composition. Pharmacological experiment has shown that the medicinal composition has good actions for preventing and treating cardiovascular and cerebrovascular diseases.

The invention relates to a heart-benefiting pulse-invigorating injection which is prepared from the raw materials of chuanxiong rhizome, schisandra chinensis volatile oil, HP-beta-CD, sun-dried ginseng, lilyturf root, astragalus root, salvia miltiorrhizae and water-soluble medicinal auxiliary materials for injection. The invention also discloses the process for preparing the injection.

The invention discloses an improved method of a bone strengthening injection production process. The method comprises the following steps: putting the caulis premnae fulvae medicine powder into an ultrasonic extraction pot, adding 40% ethanol 6-8 times the caulis premnae fulvae medicine powder in quantity, and performing ultrasonic oscillation extraction for 20-40 minutes, wherein the oscillation frequency is 50-100kHz; controlling the temperature at room temperature; extracting for 2-3 times, and filtering; combining the extracting solutions to obtain a stock solution of caulis premnae fulvae medicine; performing reduced-pressure recovery of ethanol from the stock solution of caulis premnae fulvae medicine at a temperature below 60 DEG C, and concentrating into a cream with relative density of 1.15-1.20 (50 DEG C); eluting with water through a D101 type macroporous resin adsorption column until the eluent is colorless; eluting with 40% ethanol 3-5 times the column in volume; collecting the ethanol eluent, and performing reduced-pressure recovery of ethanol at a temperature below 60 DEG C to obtain a concentrated solution of caulis premnae fulvae medicine; and producing according to the original production process to obtain a finished product. The method greatly shortens the extraction time, improves the extraction rate of active ingredients and the utilization rate of raw materials, and is simple to operate and suitable for industrial production.

The invention discloses an artemisia rupestris preparation used in medicaments for treating diabetes and a preparation method thereof. The preparation method comprises the following steps: crushing artemisia rupestris herbs; weighing the powder; adding ethyl ether of which the volume is 3 times of the volume of the powder; standing for 8 hours, and then, filtering; ultrasonically extracting precipitates with 80% ethanol at 35 DEG C for 30-40 minutes every time; filtering to obtain an ethanol extracting solution; precipitating with 95% ethanol, centrifuging, and taking a supernatant solution; extracting ethyl acetate; filtering to obtain an ethyl acetate part; carrying out polyamide column chromatography on the ethyl acetate part; eluting by sequentially adopting ethanol solutions with different concentrations of 20%, 40%, 60% and 80%; collecting ethanol eluate obtained by adopting the ethanol solutions with the concentrations of 60% and 80%; concentrating while depressurizing to obtain an extract; proportioning the obtained extract and a milk vetch extract according to the weight ratio of (5-10):1; and preparing a certain amount of pure water to obtain a finished preparation. The prepared artemisia rupestris preparation has the activity of reducing blood sugar, the using dose of the artemisia rupestris preparation is 67.5mg/kg, and the artemisia rupestris preparation has wide application fields in medicaments for treating diabetes.

The invention discloses a potato starch extraction technology. The preparation process comprises the following steps: cleaning potato and removing the peel, crushing potato until the granularity of the crushed object is 40-60 meshes, sealing to exclude the air to store for later use; placing the processed potato into a reaction pot, adding a certain amount of water until the solid-to-liquid ratio is 1:5-20, adding a certain amount of a disodium hydrogen phosphate-citric acid buffer to adjust pH to 4.1-4.4, adding 0.2-0.3 wt% of cellulose, extracting at 30-35 DEG C for 30-120min, carrying out centrifugal filtration on an extract, taking a precipitate as a green starch, and drying to obtain a product. By the adoption of the potato starch extraction technology, process wastewater discharge is reduced, an important commercial technique is provided for environmentally-friendly high-value utilization of the potato resource, potato starch industry can develop rapidly and properly, higher agricultural economic value is created, and good social benefit and economic benefit are brought for the society.

The invention belongs to the field of medical technology, which relates to an enrichment extract of Gymnema Sylvestre compound plant medicine dissolution and a preparation method. The invention utilizes an extraction technology for the compound extract of medicinal plants comprising a plurality of triterpene saponin, and the emulsification which is generated by the saponin in water and light-concentration alcohol to promote the maximum extraction for various semi-polarity and non-polar active ingredients of the other traditional Chinese medicines in the extractive compound. Compared with other traditional Chinese medicines, compound extractive of botanical drug formula and Gymnema Sylvestre unilateral extract, the Gymnema Sylvestre compound has the advantages that: the biological activity is enhanced; the toxicity of the extract is lowered, and the physical traits of the extract can be improved, so that the Gymnema Sylvestre compound can be prepared into standardized and modern preparation in small dose. Such combined extract can be taken as a drug and health product for the treatment of hyperglycemia, hyperlipemia and adiposity.

The invention discloses a grating LED (light-emitting diode) chip and a preparation method. The grating LED chip comprises a substrate; an epitaxial layer structure arranged on the substrate; a GaP layer arranged at one side, departing from the substrate, of the epitaxial layer structure; a grating layer with preset grating constant arranged at one side, departing from the epitaxial layer structure, of the GaP layer; and an electrode structure arranged on the grating layer. The grating LED chip is high in luminous efficiency, large in luminous area, and high in brightness.

The invention discloses a medicinal composition containing extracts of curcuma zedoaria and red ginseng, and preparation method and application, wherein the composition comprises the inclusion compound of significant part of aromatic turmeric oil, significant part of red ginseng extract and medicinal adjuvant, the prepared medicine has the functions of antineoplastic, antithrombotic, and antivirus. Pharmacological experiment has shown that the preparation provided by the invention has better pharmaceutical actions.

The invention relates to a preparation method of gypenoside. The method comprises the following steps: placing an extraction solvent and a gynostemma pentaphyllum herb in an ultrasonic extractor for extraction; starting an infusion pump while extracting, transferring extracting solution to a column body of an expanded bed from the bottom up, and allowing the remaining solution after adsorption byresin to return to the ultrasonic extractor to be extracted again; continuously transferring effective constituents of the gynostemma pentaphyllum from the herb to resin in the column during the dynamic extraction process; closing the ultrasonic extractor upon completion of extraction, and transferring flushing liquid to the column body of the expanded bed from the top down by the infusion pump; transferring an eluant into the column body of the expanded bed from the top down by the infusion pump after the flushing liquid becomes clear, and collecting the eluant in an automatic collector; andtransferring another eluant into the column body of the expanded bed from the top of the expanded bed down by the infusion pump upon completion of elution to complete a regeneration process of the column. The preparation method has the advantages of high efficiency, simplified steps, low cost and low energy consumption.