A kind of extracting method of active ingredient of rhubarb, a Chinese medicinal material

A technology of active ingredients and extraction method, applied in the field of extraction of active ingredients of Chinese medicinal material rhubarb, can solve problems such as content reduction, long heating time, incomplete extraction, etc., and achieve the effects of improving the extraction rate, reducing water consumption, and reducing energy consumption.

Active Publication Date: 2018-11-02
GUANGXI YULAN PHARMA CO LTD
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AI Technical Summary

Problems solved by technology

[0002] The main components of rhubarb, a traditional Chinese medicine, in hemorrhoid tablets are emodin and chrysophanol, and their content is an important indicator for drug measurement; since the above-mentioned main components of rhubarb are greatly affected by the decoction time and heating temperature, too long heating time will cause Its content is reduced, and the heating time is too short, then the extraction is incomplete. The extraction method of rhubarb in the Chinese Pharmacopoeia is: add water and decoct twice, the first time 10 times the amount of water, the second time 9 times the amount of water, because the amount of water added is relatively large. Many, longer heating time, insufficient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Put 50 kg of rhubarb, a Chinese medicinal material, into a 500L multi-functional extraction tank, add 350 kg of water for the first time, heat to boiling, keep the temperature at 96±2°C, extract for one hour, and collect the extract; add 250 kg of water for the second time, heat until boiling, keep the temperature at 96±2°C, extract for one hour, combine the two extracts, concentrate and dry to obtain 17.8 kg of dry paste.

Embodiment 2

[0014] Put 50 kg of rhubarb, a Chinese medicinal material, into a 500L multifunctional extraction tank, add 350 kg of water for the first time, heat to boiling, keep the temperature at 96±2°C, extract for one hour, and collect the extract; add 300 kg of water for the second time, heat To boiling, keep the temperature at 96±2°C, extract for one hour, combine the two extracts, concentrate and dry to obtain 17.2 kg of dry paste.

Embodiment 3

[0016] Put 50 kg of rhubarb, a Chinese medicinal material, into a 500L multi-functional extraction tank, add 400 kg of water for the first time, heat to boiling, keep the temperature at 96±2°C, extract for one hour, and collect the extract; add 250 kg of water for the second time, heat To boiling, keep the temperature at 96±2°C, extract for one hour, combine the two extracts, concentrate and dry to obtain 18.1 kg of dry paste.

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PUM

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Abstract

The invention discloses an extraction method of active ingredients of a traditional Chinese medicinal material rhubarb, belonging to the technical field of traditional Chinese medicine extraction and aiming to provide a new rhubarb extraction method with high efficiency and good extraction effects. The extraction method is characterized in that extraction is carried out by adopting twice water extraction modes, wherein the extraction conditions are as follows: 7-8 times amount of water is added during first extraction, 5-6 times amount of water is added during second extraction, the temperature is maintained at 96+ / -2 DEG C after boiling, and the extraction time every time is one hour. The method is mainly used for extracting the active ingredients of the traditional Chinese medicinal material rhubarb.

Description

technical field [0001] The invention relates to a technology for extracting Chinese medicinal materials, more specifically, it relates to a method for extracting effective components of rhubarb, a traditional Chinese medicinal material. Background technique [0002] The main components of rhubarb, a traditional Chinese medicine, in hemorrhoid tablets are emodin and chrysophanol, and their content is an important indicator for drug measurement; since the above-mentioned main components of rhubarb are greatly affected by the decoction time and heating temperature, too long heating time will cause Its content is reduced, and the heating time is too short, then the extraction is incomplete. The extraction method of rhubarb in the Chinese Pharmacopoeia is: add water and decoct twice, the first time 10 times the amount of water, the second time 9 times the amount of water, because the amount of water added is relatively large. Many, the heating time is longer, and there are defici...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/708
CPCA61K36/708A61K2236/331A61K2236/39
Inventor 张盈盈赖丽雯尹中秋陈远强
Owner GUANGXI YULAN PHARMA CO LTD
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