The invention discloses a method for detecting residues of chloramphenicols in milk products. Chloramphenicols include chloramphenicol, thiamphenicol and florfenicol. The method comprises the following steps: carrying out pretreatment on a to-be-detected sample: weighing m1g of the to-be-detected sample, adding v1ml of ethyl acetate for extraction to obtain a first extract, dissolving the first extract by virtue of v2ml of methanol, adding v3ml of normal hexane, mixing uniformly, carrying out centrifuging, abandoning superstratum to obtain a second extract, and purifying the second extract by virtue of a solid phase extraction column, so as to obtain purified substances; analyzing the purified substances by virtue of a liquid phase-tandem mass spectrometer, and detecting the residues of the chloramphenicols in the to-be-detected sample, wherein m1 is less than or equal to 5, v1 is less than 20, v2 is less than 1, and v3 is less than 8. According to the method, an interior label is not required, so that an emulsification phenomenon in the detection process can be avoided, and the interference caused by a matrix to the detection can be reduced; chloramphenicol drugs can be simultaneously detected, the sensitivity and the recovery rate are high, the cost is saved, and the operation is easy.