The invention relates to the technical field of health wine, in particular to health wine capable of reinforcing the kidney to strengthen yang and a preparation method of the health wine. The health wine is processed from raw materials by mass as follows: 3,000-30,000 g of Dendrobium officinale, 1,500-15,000 g of mulberries, 1,000-10,000 g of sharpleaf galangal fruits, 1,000-10,000 g of wolfberries, 1,000-10,000 g of peach seeds, 500-5,000 g of ginseng, 500-5,000 g of jujube kernels, 250-2,500 g of cinnamon, 250-2,500 g of liquorice, 500-10,000 g of white granulated sugar and 220,000-450,000 g of a wine matrix. The health wine has the effects of reinforcing the kidney, refilling essence, benefiting marrow, and promoting blood circulation to remove meridian obstruction, can build fitness and prolong life and is suitable for modern people to drink. The preparation method has simple and mature process and good economic benefit and facilitates popularization and application.