Traditional Chinese medicine composition for treating acute dampness-warmness skin diseases and preparation method of traditional Chinese medicine composition

A technology for damp-heat skin diseases, which is applied in the field of traditional Chinese medicine composition for treating acute damp-heat skin diseases and its preparation field, can solve problems such as side effects and lack of eczema treatment measures, and achieve improved rate of presentation, strong heat-clearing and damp-dampening effect, and increased The effect of the therapeutic effect

Inactive Publication Date: 2017-09-01
北京市中医研究所 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the commonly used oral drugs for the treatment of eczema in western medicine mainly include antihistamines, glucocorticoids, immunosuppressants, non-specific anti-allergic drugs, etc., but long-term use will cause a series of side effects. , economical and practical eczema treatment measures

Method used

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  • Traditional Chinese medicine composition for treating acute dampness-warmness skin diseases and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating acute dampness-warmness skin diseases and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating acute dampness-warmness skin diseases and preparation method of traditional Chinese medicine composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] 1. Extraction process research

[0049] 1. Research on extraction method

[0050] According to the physical and chemical properties of the main chemical components of each herb in the prescription and their related pharmacological effects, a classification extraction method (alcohol extraction and water extraction) was designed; taking the main component content and anti-inflammatory effect as evaluation indicators, the classification extraction method and Traditional water decoction method, the results are shown in Table 1 and Table 2. The content of gentiopicroside in the monarch drug Gentiana and the content of baicalin in the ministerial drug Scutellaria baicalensis are greater than the traditional water decoction method, and the inhibitory effect of xylene-induced mouse ear swelling is stronger than the traditional water decoction method. , determine the extraction method as classification extraction method.

[0051] Table 1 Comparison of content determination resu...

Embodiment 2

[0088] The preparation method of the granule of the traditional Chinese medicine composition for the treatment of acute damp-heat skin disease, the steps are as follows:

[0089] Get each raw material of following weight portion:

[0090] 9 parts of gentian, 9 parts of skullcap, 12 parts of plantain, 30 parts of imperina root, 15 parts of rehmannia root, 10 parts of poria cocos, 15 parts of isatidis root, 30 parts of raw gypsum, 2.1 parts of licorice, 12.9 parts of talcum powder;

[0091] Add gentian, scutellaria baicalensis and plantain with 12 times the mass concentration of 70% ethanol aqueous solution, extract 3 times, each time for 1.5 hours, filter, recover ethanol from the filtrate until it has no alcohol smell, and obtain the ethanol extract;

[0092] Add 8 times the amount of water to soak in 8 times the amount of water for 30 minutes, extract 3 times, each time for 2 hours, and obtain the water extract;

[0093] Mixing the alcohol extract and the water extract, conc...

Embodiment 3

[0098] The preparation method of the granule of the traditional Chinese medicine composition for the treatment of acute damp-heat skin disease, the steps are as follows:

[0099] Get each raw material of following weight portion:

[0100] 8 parts of gentian, 8 parts of skullcap, 10 parts of plantain, 25 parts of imperina root, 13 parts of rehmannia root, 8 parts of poria cocos, 13 parts of isatidis root, 25 parts of raw gypsum, 1.5 parts of licorice, 9 parts of talcum powder;

[0101] Add gentian, scutellaria baicalensis and plantain with 10 times the mass concentration of 75% ethanol aqueous solution, extract 4 times, each time for 1 hour, filter, recover ethanol from the filtrate until it has no alcohol smell, and obtain the alcohol extract;

[0102] Add 5 times the amount of water and soak for 20 minutes, extract twice, each time for 3 hours, to obtain the water extract;

[0103] mixing the alcohol extract and the water extract, and concentrating to 1.5 times the weight of...

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Abstract

The invention relates to the field of traditional Chinese medicine treatment for skin diseases, in particular to a traditional Chinese medicine composition for treating acute damp-heat skin diseases and a preparation method thereof. A traditional Chinese medicine composition for treating acute damp-heat dermatosis, mainly made from the following raw materials: by weight, 8-10 parts of gentian, 8-10 parts of skullcap, 10-15 parts of plantain, 25- parts of Rhizoma Imperatae 35 parts, 13-18 parts of Rehmannia glutinosa, 8-12 parts of Poria, 13-18 parts of Banlangen, 25-35 parts of raw gypsum, 1.5-2.5 parts of licorice, 9-15 parts of talcum powder. The traditional Chinese medicine composition for treating acute damp-heat skin disease provided by the present invention, the combination of various medicines makes the prescription strong in clearing heat and dampness, and has the effect of cooling blood. , drug eruption and other acute damp-heat skin diseases have a good therapeutic effect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine treatment of skin diseases, in particular to a traditional Chinese medicine composition for treating acute damp-heat skin diseases and a preparation method thereof. Background technique [0002] Dermatological diseases such as eczema and dermatitis are the most common pruritic skin diseases. Eczema accounts for about 52.4%. Modern medicine believes that eczema is an allergic inflammatory skin disease, which is a skin inflammatory reaction with pleomorphic skin lesions and a tendency to exudate caused by a variety of complex internal and external factors. At present, the commonly used oral drugs for the treatment of eczema in western medicine mainly include antihistamines, glucocorticoids, immunosuppressants, non-specific anti-allergic drugs, etc., but long-term use will cause a series of side effects. , Economical and practical eczema treatment measures. Chinese medicine treatment of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P17/00A61P31/22A61K33/06A61K33/12
CPCA61K36/515A61K33/06A61K33/12A61K36/076A61K36/195A61K36/315A61K36/484A61K36/539A61K36/68A61K36/804A61K36/899A61K2236/331A61K2236/333A61K2236/39
Inventor 李萍曾祖平周冬梅何薇韩旭阳
Owner 北京市中医研究所
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