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Pharmaceutical composition for treating dermatitis due to ionizing radiation

A composition and technology of dermatitis, applied in the field of medical invention, can solve problems such as cortical shrinkage, aggravation of infection, and influence on hormone secretion, and achieve obvious effects, significant curative effect, and good promotion value

Inactive Publication Date: 2016-09-28
修新军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, hormone therapy has many side effects. Long-term use can induce or aggravate infection, affect the normal hormone secretion of the body, and cause cortical shrinkage after discontinuation. Therefore, there is an urgent need for a drug that can prevent and treat radiation dermatitis without toxic side effects. drug

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Prescription: Mustard Seed 10g, Two Tips 10g, Perilla Stem 10g, Gecko 5g, Muscarina 10g, Vasong 10g, Tianxianzi 5g, Aconite 5g, Baiqian 10g, Kochia 10g, Licorice 10g.

[0038] Preparation:

[0039] 1) Take the medicine in parts by weight for subsequent use;

[0040] 2) Decoct mustard seeds, two tips, perilla stalks, sinensis, vasong, celestia chinensis, Baiqian, Kochia chinensis, and licorice with 3 times the amount of water for 1 hour each time, filter, combine the filtrates, and decoct the filtrates Concentrate, dry, crush into fine powder, and set aside;

[0041] 3) Stir-fry gecko and white aconite over medium heat for 5 minutes, add 2 times the amount of 65% ethanol to soak for 10 hours, filter, concentrate the filtrate, dry, and grind into fine powder for later use;

[0042] 4) Mix the fine powders in steps 2) and 3) uniformly, add starch accounting for 1 / 5 of the weight of the uniformly mixed fine powders, and pack into capsules to make capsules.

Embodiment 2

[0044] Prescription: 60g of mustard seed, 60g of two tips, 55g of perilla stalk, 30g of gecko, 60g of tendon grass, 50g of vasong, 25g of Tianxianzi, 25g of white aconite, 40g of Baiqian, 50g of Kochia scoparia, 60g of licorice.

[0045] Preparation:

[0046] 1) Take the medicine in parts by weight for subsequent use;

[0047] 2) Decoct mustard seeds, two-end tips, perilla stalks, sinensis, vasong, celestia chinensis, Baiqian, Kochia scoparia, and licorice with 6 times the amount of water for 4 times, each time for 3 hours, filter, combine the filtrates, and decoct the filtrates Concentrate, dry, crush into fine powder, and set aside;

[0048] 3) Stir-fry gecko and white aconite with medium heat for 10 minutes, add 5 times the amount of 85% ethanol to soak for 30 hours, filter, concentrate the filtrate, dry, and grind into fine powder for later use;

[0049] 4) Mix the fine powders in steps 2) and 3) uniformly, add starch accounting for 1 / 5 of the weight of the uniformly mix...

Embodiment 3

[0051]Prescription: 15g mustard seed, 15g two tips, 15g perilla stalk, 10g gecko, 15g sinensis, 15g vasong, 8g tianxianzi, 8g white aconite, 15g white front, 15g Kochia scoparia, 15g licorice.

[0052] Preparation:

[0053] 1) Take the medicine in parts by weight for subsequent use;

[0054] 2) Decoct mustard seed, two-headed tip, perilla stalk, sinensis, vasong, angelica, white front, Kochia chinensis, and licorice with 5 times the amount of water for 3 times, each time for 2 hours, filter, combine the filtrate, and decoct the filtrate Concentrate, dry, crush into fine powder, and set aside;

[0055] 3) Stir-fry gecko and white aconite over medium heat for 8 minutes, add 3 times the amount of 75% ethanol to soak for 20 hours, filter, concentrate the filtrate, dry, and grind into fine powder for later use;

[0056] 4) Mix the fine powder of steps 2) and 3) evenly, add starch accounting for 1 / 5 of the weight of the evenly mixed fine powder, mix evenly, granulate, dry, and gra...

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PUM

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Abstract

The invention relates to a pharmaceutical composition for treating dermatitis due to ionizing radiation and a preparation method thereof. The pharmaceutical composition is prepared by the following medicines in parts by weight: mustard seeds, Radde anemone rhizome, perilla stems, gecko, Ajuga ciliate, orostachys, henbane seeds, typhonium rhizomes, willowleaf swallowwort rhizomes, Kochia scoparia, and licorice; the pharmaceutical composition is prepared by processes of decoction with water, stir frying with fire, and alcohol leaching. The pharmaceutical composition was used for treating 270 patients with dermatitis due to ionizing radiation, the total effective rate reaches 94.4%, effects are obvious, and adverse reactions as well as toxic and side effects are not discovered; the pharmaceutical composition has substantial curative effects for treating dermatitis due to ionizing radiation, and has good promotion values.

Description

technical field [0001] The invention relates to the field of medical inventions, in particular to a pharmaceutical composition for treating radiation dermatitis and a preparation method thereof. Background technique [0002] Radiation dermatitis is the inflammatory damage caused by various ionizing radiations including X-rays and radioisotopes irradiating the skin and mucous membranes. Although people's awareness of radiation and the improvement of protective measures have greatly improved their awareness of such diseases, but with the continuous popularization of radiation in medical diagnosis and treatment and the continuous development of the atomic energy industry, people exposed to The chance of radiation is constantly increasing, so the disease has an increasing trend. Various types of ionizing radiation can cause the skin to respond to varying degrees, and they are consistent with the basic lesion of biological tissue damage, that is, the DNA of the nucleus absorbs r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61P17/00A61K35/583
CPCA61K36/31A61K35/583A61K36/185A61K36/27A61K36/41A61K36/484A61K36/53A61K36/535A61K36/71A61K36/81A61K36/888A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 修新军
Owner 修新军
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