Poison bait capable of inhibiting rat reproduction and preparation method thereof

A bait and rodent technology, applied in the fields of botanical equipment and methods, chemicals for biological control, animal repellents, etc. Unstable sterile effect and other problems, to achieve the effect of long duration of drug effect, reduction of secondary pollution, and good palatability

Active Publication Date: 2016-10-12
SHAANXI INST OF ZOOLOGY NORTHWEST INSTOF ENDANGERED ZOOLOGICAL SPECIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the currently used sterile agents still have problems such as poor palatability, unstable sterile effect, and poor universality.
Moreover, the current medicinal baits are generally prepared by directly mixing and granulating the sterile agent and food materials. When exposed to natur

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1 Calcium Carbonate Porous Carrier / Cyclodextrin Coating Layer Composite Medicinal Bait

[0027] Prepare a solution containing sodium polystyrene sulfonate and calcium nitrate, use sodium carbonate as a precipitant to precipitate calcium carbonate porous microspheres; dissolve desogestrel, ethinyl estradiol, peanut powder, and nonionic surfactants in water to configure To form an impregnating liquid, the weight ratio of desogestrel, ethinyl estradiol and peanut powder is 75:25:400, adding calcium carbonate porous microspheres into the impregnating liquid, fully mixing, heating and evaporating to obtain loaded desogestrel, Calcium carbonate porous microspheres of ethinyl estradiol and peanut powder; prepare a saturated aqueous solution of cyclodextrin, spray the saturated aqueous solution of cyclodextrin onto the porous calcium carbonate microspheres, and then heat and stand at 50°C for 12 hours to obtain cyclodextrin Fine coated calcium carbonate porous microsphe...

Embodiment 2

[0028] Example 2 Polylactic Acid Porous Carrier / Gelatin Coating Layer Composite Medicinal Bait

[0029] To prepare a solution of polylactic acid in dichloromethane, use CO 2Supercritical drying to polylactic acid porous microspheres; dissolving desogestrel, ethinyl estradiol, peanut powder, and nonionic surfactants in 33% ethanol aqueous solution to prepare an impregnation solution, desogestrel, ethinyl estradiol and peanut The weight ratio of the powder is 80:20:300. Add polylactic acid porous microspheres into the impregnating liquid, mix well, heat and evaporate to obtain polylactic acid porous microspheres loaded with desogestrel, ethinyl estradiol and peanut powder; prepare A saturated aqueous solution of gelatin, impregnating the polylactic acid porous microspheres with a saturated aqueous solution of gelatin, then heating and standing at 80° C. for 5 hours, to obtain polylactic acid porous microspheres coated with gelatin; prepare the food material, and the food materia...

Embodiment 3

[0030] Example 3 Chitosan Porous Carrier / Cyclodextrin Coating Layer Composite Medicinal Bait

[0031] Prepare chitosan acetic acid solution, add glutaraldehyde to chemically cross-link to obtain chitosan porous microspheres; dissolve desogestrel, ethinyl estradiol, peanut powder, and nonionic surfactants in water to prepare an impregnating solution, deoxidize The weight ratio of pregnene, ethinyl estradiol and peanut powder is 60:40:700. Add chitosan porous microspheres into the impregnation solution, mix well, heat and evaporate to obtain desogestrel, ethinyl estradiol and peanut powder Polylactic acid porous microspheres; prepare a saturated aqueous solution of cyclodextrin, impregnate chitosan porous microspheres with a saturated aqueous solution of cyclodextrin, then heat and stand at 60°C for 10 hours to obtain cyclodextrin-coated chitosan Porous microspheres; Prepare food material, said food material is made of 15% soy flour, 58% flour, 8% fish meal, 15% peanut powder, 2...

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Abstract

The invention provides a poison bait capable of inhibiting rat reproduction. The poison bait comprises a component particle A and a component particle B. The component particle A is a compound bait adopting a multilayer structure, the compound bait adopting the multilayer structure comprises a degradable porous carrier which is loaded with a chemosterilant and peanut flour, a biodegradable coating layer which can internally coat the degradable porous carrier and the chemosterilant and the peanut flour loaded on the degradable porous carrier, and a food layer which comprises foods and coats the biodegradable coating layer internally in sequence from inside to outside, wherein the chemosterilant is desogestrel and ethinyloestradiol. The component particle B is a food particle. The poison bait disclosed by the invention is conducive to long-term and all-weather application, especially the sublimation, degradation or loss of effective components are avoided when the poison bait is applied and released in the field or in the wild, so that secondary pollution to the environment is not caused, and the palatability of the poison bait is good.

Description

technical field [0001] The invention relates to a rodent-killing bait and a preparation method thereof, in particular to a bait capable of inhibiting rodent reproduction and a preparation method thereof. Background technique [0002] The traditional method of controlling the number of pests - the extermination method, will bring about the problems of short control effect, rapid population recovery and poisoning of non-target animals, and the method of extermination is also accused by animal rights organizations for being "inhumane" . Especially the method of chemical rodent control, although it can temporarily reduce the rodent density within a certain range and time, but the ensuing environmental pollution, secondary poisoning, and rodent refusal to eat due to long-term use of rodenticides, Issues such as the emergence of drug resistance and adaptability cannot be ignored. At the same time, the use of rodenticides has played the role of "artificial selection" on rodents, ...

Claims

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Application Information

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IPC IPC(8): A01N45/00A01N25/08A01N25/10A01N25/26A01P19/00A01P23/00
CPCA01N25/08A01N25/10A01N25/26A01N45/00
Inventor 常罡陈晓宁韩宁侯祥靳铁治张博陈雅娟王京封托申健
Owner SHAANXI INST OF ZOOLOGY NORTHWEST INSTOF ENDANGERED ZOOLOGICAL SPECIES
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