Application of Forsythin, Forsythin Derivatives, Forsythin and Forsythin Composition in Preparation of Drugs for Alleviating or/and Treating Vomiting

The technology of a forsythin derivative and forsythiacin, which is applied in the field of medicine, can solve the problems of delayed vomiting and poor curative effect, and achieve the effects of strong pharmacological action, good medicinal prospect and good safety.

Active Publication Date: 2020-02-11
富力
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It has a wide range of tolerance, few side effects, and has obvious curative effect on acute vomiting, but some studies have found that 5-HT 3 Receptor antagonists are less effective in delayed emesis

Method used

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  • Application of Forsythin, Forsythin Derivatives, Forsythin and Forsythin Composition in Preparation of Drugs for Alleviating or/and Treating Vomiting
  • Application of Forsythin, Forsythin Derivatives, Forsythin and Forsythin Composition in Preparation of Drugs for Alleviating or/and Treating Vomiting
  • Application of Forsythin, Forsythin Derivatives, Forsythin and Forsythin Composition in Preparation of Drugs for Alleviating or/and Treating Vomiting

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Embodiment 1 forsythin tablet

[0042] 1. Prepare raw materials according to the following ratio

[0043]

[0044] 2. Mix forsythin and starch evenly, make granules, add talcum powder and magnesium stearate, mix evenly, and press into 10,000 tablets.

Embodiment 2

[0045] Embodiment 2 forsythin capsules

[0046] 1. Prepare raw materials according to the following ratio

[0047] Forsythin (purity 60%) 200g

[0048] Starch 1000g

[0049] 2. Mix forsythin and starch evenly and pack into capsules to make 10,000 capsules.

Embodiment 3

[0050] Embodiment 3 forsythin capsules

[0051] 1. Prepare raw materials according to the following ratio

[0052] Forsythin (purity 98%) 500g

[0053] Starch 1000g

[0054] 2. Mix forsythin and starch evenly and pack into capsules to make 10,000 capsules.

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Abstract

The invention discloses new application of phillyrin, phillyrin derivatives, and a phillyrin-phillygenin composition in preparation of drugs or health care products for relief or / and treatment of vomiting. Tests prove that the phillyrin, phillyrin derivatives, and phillyrin-phillygenin composition have the characteristics of significant vomiting relief or treatment effect, quick effect and small toxic and side effect, are a safe, efficient and stable vomiting treatment drug with a simple preparation process, and are suitable for industrial production and easy for popularization. The invention provides a new drug source for prevention and treatment of vomiting and its complications.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a medicine for treating vomiting, in particular to an application of traditional Chinese medicine forsythia and forsythia leaf extract components in medicine for alleviating or / and treating vomiting. Background technique [0002] Vomiting is a defensive reaction involving the peripheral and central nervous systems. It is a phenomenon in which the contents of the stomach are excreted reflexively through the esophagus and oral cavity due to the strong joint contraction of the diaphragm and abdominal muscles. Vomiting can remove harmful substances in the stomach. discharge. Many factors can cause nausea and vomiting, such as labyrinth stimulation, after surgery, internal organ pain, pregnancy, vestibular stimulation, etc. Chemotherapy and radiotherapy, the current important means of cancer treatment, lead to strong nausea and vomiting, which not only affect the appetite and digestion of tum...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61K36/9064A61K36/9062A61K36/754A61K36/899A61K36/8888A61K36/532A61K36/835A61K36/28A61K36/535A61K36/61A61K36/73A23L33/00A61P1/08A61K31/34A61K31/375
Inventor 王凯乾富力惠敏鲁明明王硕樊宏宇柳洋盖鑫周庆丰
Owner 富力
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