Traditional Chinese medicine composition improving dementia and preparation method and application thereof

A dementia and composition technology, applied in the field of traditional Chinese medicine, can solve the problems of no effective treatment measures, achieve the effect of improving the shape and quantity, and reducing the plaque area

Active Publication Date: 2016-11-23
北京润康普瑞生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many studies in various aspects of the world, but there is still no effective treatment

Method used

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  • Traditional Chinese medicine composition improving dementia and preparation method and application thereof
  • Traditional Chinese medicine composition improving dementia and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] The preparation of each component in the Chinese medicine composition of embodiment 1

[0035] Anemarrhena extract: dry and pulverize Anemarrhena, reflux extraction with 75% ethanol for 3 times, each time for 2 hours, each time the ratio of solid to liquid is 1:8, combine the extracts, filter, and spray the filtrate into powder ;

[0036] Ginkgo biloba extract: Ginkgo biloba is dried and pulverized, refluxed and extracted with 65% ethanol for 3 times, each time for 1.5 hours, each time the ratio of solid to liquid is 1:6, combined extracts, filtered under reduced pressure, combined filtrates, and The filtrate is spray-dried into powder;

[0037] Turmeric extract: dry the rhizome of Turmeric and make it into powder, extract it with 95% ethanol for 1 hour, concentrate the extract, crystallize it, and dry it;

[0038] Soybean lecithin: add 2-3% water to soybean crude oil, heat to 75°C under stirring, hydrate the phospholipids into colloidal phospholipid slurry, centrifug...

Embodiment 2

[0047] The capsule preparation of embodiment 2 Chinese medicine composition

[0048] Prepared according to Example 1: Anemarrhena anemarrhena extract 300g, Ginkgo biloba extract 300g, turmeric extract 200g, soybean lecithin 300g, Rhodiola rosea extract 100g, Polygala extract 300g, Yizhiren extract 300g, Green tea extract 300g, grape seed extract 200g, phosphatidylserine 200g, Y-aminobutyric acid 200g, Antarctic krill oil powder 200g and pomegranate polyphenol 100g.

[0049] The method for preparing the above-mentioned Chinese medicine composition into capsules:

[0050] Anemarrhena extract, Ginkgo biloba extract, Turmeric extract, Soy lecithin, Rhodiola rosea extract, Polygala extract, Yizhi kernel extract, Green tea extract, Grape seed extract, Phosphatidylserine, Y - After GABA, Antarctic krill oil powder and pomegranate polyphenols are mixed evenly, 4g of silicon dioxide is added, and capsules are filled to obtain the product, wherein each capsule contains 0.5g of the abov...

Embodiment 3

[0051] The powder preparation of embodiment 3 Chinese medicine composition

[0052] Take prepared according to Example 1: Anemarrhena anemarrhena extract 260g, Ginkgo biloba extract 300g, turmeric extract 180g, soybean lecithin 320g, Rhodiola rosea extract 90g, Polygala extract 340g, Yizhiren extract 280g, Green tea extract 320g, grape seed extract 240g, phosphatidylserine 180g, Y-aminobutyric acid 200g, Antarctic krill oil powder 210g and pomegranate polyphenol 110g.

[0053] The method for preparing the above-mentioned Chinese medicine composition into a powder:

[0054] Anemarrhena extract, Ginkgo biloba extract, Turmeric extract, Soy lecithin, Rhodiola rosea extract, Polygala extract, Yizhi kernel extract, Green tea extract, Grape seed extract, Phosphatidylserine, Y - After GABA, Antarctic krill oil powder and pomegranate polyphenols are evenly mixed, 10 g of magnesium stearate is added, and the powder is packed into bags, wherein each bag contains 1.5 g of the above-ment...

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Abstract

The invention discloses a traditional Chinese medicine composition improving dementia and a preparation method and application thereof. The traditional Chinese medicine composition improving the dementia is prepared from a rhizoma anemarrhenae extract, a folium ginkgo extract, a rhizoma curcumae longae extract, soybean lecithin, a kirilow rhodiola root extract, a radix polygalae extract, a sharpleaf galangal fruit extract, a green tea extract, a grape seed extract, phosphatidylserine, Y-aminobutyric acid, euphausia superba oil powder and punicosides. The traditional Chinese medicine composition can obviously decrease the beta-AP plaque area inside the brain, forms and number of nerve cells around an injection region and in a more distant region can be obviously improved, and a protective effect on the neuronal toxicity caused by beta-AP is achieved. Meanwhile, according to the experiment, an objective basis is provided for further researching and developing the traditional Chinese medicine for treating the dementia by researching the reaction and action mechanism of a traditional Chinese medicine composition dementia animal model.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for improving dementia and its preparation method and application. The invention belongs to the technical field of traditional Chinese medicine. Background technique [0002] With the development of society and the aging of the population, people's mental health diseases are becoming more and more prominent, especially dementia, which is the most harmful. A kind of primary brain atrophy, that is, in the state of no disturbance of consciousness, there are obstacles in memory, thinking, analysis and judgment, visuospatial recognition, emotion, etc. The patient lives a life of dependence. The disease seriously affects the quality of life of patients and brings heavy burden to the country, society and family. With the increase of the elderly population in the future, the number of patients will continue to increase. Therefore,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/48A61K9/20A61K9/16A23L33/00A61P25/28A61K31/197A61K31/685A61K35/612
CPCA23V2002/00A61K9/1652A61K9/2059A61K9/485A61K9/4858A61K31/197A61K31/685A61K35/612A61K36/16A61K36/185A61K36/41A61K36/48A61K36/69A61K36/82A61K36/87A61K36/8964A61K36/9062A61K36/9066A61K2300/00A23V2200/322
Inventor 王志文
Owner 北京润康普瑞生物技术有限公司
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