603results about "Crustacean material medical ingredients" patented technology

This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and / or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical CO2 or CO2 plus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical CO2 in combination with approximately 20% ethanol. The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.

A phospholipid extract from a marine or aquatic biomass possesses therapeutic properties. The phospholipid extract comprises a variety of phospholipids, fatty acid, metals and a novel flavonoid.

Methods and compositions for the prevention, therapy and / or treatment of several disease states. The methods comprise the administration of a therapeutically effective amount of a composition including krill extract and conjugated linoleic acid. In addition, the present invention provides new and improved therapeutic compositions including krill extracts and conjugated linoleic acid.

The present invention relates to a method of treatment and / or prevention of cardiovascular disease, rheumatoid arthritis, skin cancer, premenstrual syndrome, diabetes and transdermal transport enhancement. The method comprises the administration of a therapeutically effective amount of krill and / or marine oil to a patient. The present invention also relates to a composition for the treatment and / or prevention of these diseases.

A new method for krill meal production has been developed using a two step cooking process. In the first step the proteins and phospholipids are removed from the krill and precipitated as a coagulum. In the second stage the krill without phospholipids are cooked. Following this, residual fat and astaxanthin are removed from the krill using mechanical separation methods. A novel krill meal product with superior nutritional and technical properties is prepared.

The invention discloses an externally-used plaster which is prepared from more than 80 kinds of Chinese medicinal materials including frankincense, myrrh, mercurous chloride, dragon's blood resin, camphor, boneol, orpiment, sulfur, gamboge, lead monoxide, native copper, white alum, colophony, dragon's blood resin, musk, orpiment, lead monoxide, alkanna tinctoria, colophony, buck grass, wasp's nest, camphor, mercurous chloride, wood louse, and can be used for treating rheumatic arthritis and proliferative arthritis.

The invention relates to processing crustaceans such as krill to oils comprising phospholipids that are Newtonian fluids and / or and have low viscosity, and in particular to the production of oils containing astaxanthin and phospholipids that show Newtonian fluidity and have a low viscosity.

Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and / or rheumatoid arthritis have been found with krill oil and / or marine oil in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.

Organic solvent-free processes for obtaining krill oil compositions are disclosed. The processes include a) cooking krill in a cooker vessel for a time and at a temperature sufficient to denature the protein content of the krill and cause a first solid krill fraction and a first liquid krill fraction to be formed while substantially avoiding emulsification of the first solid and first liquid hill fractions; b) removing the first solid and first liquid krill fractions from the cooker vessel at a temperature of at least about 90° C.; c) separating the first solid fraction and the first liquid fraction; and d) obtaining krill oil with neutral enriched from the first liquid fraction, and e) by pressing of first solid fraction to obtain press liquid or a second liquid krill fraction for obtaining hill oil with phospholipids enriched krill oil, the separating and the obtaining steps being carried out without the use of organic solvents. Krill oil compositions made by the process are also disclosed.

The present disclosure provides for novel krill oil-based compositions, method of administration and method of manufacture which provide for the treatment and prevention of cardiovascular disease, including the reduction of one or more significant risk factors involved with cardiovascular disease. The active ingredients of the composition include krill oil, combined in one embodiment with niacin, and combined in an alternate embodiment with polymethoxylated flavones (PMFs), and combined in yet another embodiment with Cissus quadrangularis, and combined in a further embodiment with Gynostemma pentaphyllum.

The present invention relates to a method of treatment and / or prevention of cardiovascular disease, rheumatoid arthritis, skin cancer, premenstrual syndrome, diabetes and transdermal transport enhancement. The method comprises the administration of a therapeutically effective amount of krill and / or marine oil to a patient. The present invention also relates to a composition for the treatment and / or prevention of these diseases.

This invention discloses methods of using krill oil and compositions comprising krill oil to treat risk factors for metabolic, cardiovascular, and inflammatory disorders. The present invention also relates to methods of using compositions comprising krill oil to modulate biological processes selected from the group consisting of glucose metabolism, lipid biosynthesis, fatty acid metabolism, cholesterol biosynthesis, and the mitochondrial respiratory chain. The present invention further includes pharmaceutical and / or nutraceutical formulations made from krill oil, methods of making such formulations, and methods of administering them to treat risk factors for metabolic, cardiovascular, and inflammatory disorders.

The invention relates to a health-care medicated wine and a preparation method thereof. The health-care medicated wine comprises the following components: cervus elaphus linnaeus, spotted deer antler slice, sea horse, kidneys of horse and deer, kidney of donkey, kidney of dog, gecko, herba epimedii, morinda officinalis, Chinese chive seed, dried shrimps, cistanche, the seed of Chinese dodder, babchi seed, flastem milkvetch seed, fenugreek, cinnamon, ootheca mantidis, rhizoma drynariae, honey, crystal sugar and white spirit. In the invention, by adopting the traditional compatibility principle, the health-care medicated wine has the functions of tonifying Qi and strengthening kidney, replenishing essence and nourishing medulla, regulating the balance of Yin and Yang, enhancing sex function, improving immunity and the like, and has the advantages of exquisite material selection, strict preparation process and no bad and side effects.

The present disclosure provides for novel krill oil-based compositions, method of administration and method of manufacture which provide for the treatment and prevention of cardiovascular disease, including the reduction of one or more significant risk factors involved with cardiovascular disease. The active ingredients of the composition include krill oil, combined in one embodiment with niacin, and combined in an alternate embodiment with polymethoxylated flavones (PMFs), and combined in yet another embodiment with Cissus quadrangularis.

This invention discloses methods of using krill oil and compositions comprising krill oil to treat risk factors for metabolic, cardiovascular, and inflammatory disorders. The present invention also relates to methods of using compositions comprising krill oil to modulate biological processes selected from the group consisting of glucose metabolism, lipid biosynthesis, fatty acid metabolism, cholesterol biosynthesis, and the mitochondrial respiratory chain. The present invention further includes pharmaceutical and / or nutraceutical formulations made from krill oil, methods of making such formulations, and methods of administering them to treat risk factors for metabolic, cardiovascular, and inflammatory disorders.

The present invention relates to the field of nutritional support for individuals and reducing the effects of muscle conditions caused by high levels of physical activity. In particular, the invention provides dietary formulations, compositions comprising these formulations and uses of these compositions to support the body's muscle regeneration process.

A medicine delivery system includes an inner capsule containing carotenoids and an outer capsule in which the inner capsule is contained within the outer capsule and the outer capsule containing a therapeutically effective amount of krill oil. In one example, the carotenoids comprise at least S, S′-astaxanthin derived from Haematococcus pluvialis, and one or more of lutein and / or trans-zeaxanthin or meso-zeaxanthin. The medicine delivery system also includes 0.5 to 8 mg of astaxanthin, 2 to 15 mg of lutein and 0.2 to 12 mg of trans-zeaxanthin contained within the inner capsule. In a specific example, the medicine delivery system includes about 4 mg of astaxanthin, about 10 mg of lutein and about 1.2 mg of trans-zeaxanthin contained within the inner capsule.

The invention discloses a deer-horn gelatin health product for conditioning eight types of abnormal body constitution. The deer-horn gelatin health product comprises the following raw materials in parts by mass: 1-10 parts of deer-horn gelatin powder, 1-10 parts of panax ginseng, 1-10 parts of cordyceps militaris, 0.1-4 parts of tissue culture of saussurea involucrate, 1-6 parts of polygonatum sibiricum and 1-4 parts of radix polygonati officinalis, into which the following materials can be added: sanguis cervi, deer bone meal, lepidium meyenii walp, moringa oleifera leaves, earthworm protein, noni berry smoothie, Chinese wolfberries, fructus mori, phyllanthus emblica, dunaliella salina, white hyacinth beans, arillus longan, semen cassiae torae, lilium brownie, semen euryales, hippophae rhamnoides, alpinia oxyphylla, fructus jujubae, herba elsholtziae, semen ziziphi spinosae, poria cocos, fructus citri sarcodactylis, citrus medica, exocarpium citri rubrum, peach kernels, tortoise, coix seeds, lonicera japonica, licorice, semen ginkgo, Chinese yam, carica papaya, myristica fragrans, pollen pini, rosa roxburghii, eucommia staminate flower, flos rosae rugosae, euryale ferox, linderae aggregate leaves, honey, krill oil, sacha inchi oil, wheat oligopeptides, yeast beta-glucosan, milk minerals, tomato seed oil and eucommia seed oil. The deer-horn gelatin health product provided by the invention has a good curative effect for people with qi-blood deficiency and viscera function failures and for low-immunity sub-healthy groups with all kinds of deficiency syndromes.

The invention discloses a traditional Chinese medicine composition for treating bone fracture diseases, which is prepared into a medicine for internal use from certain weight parts of Chinese angelica, pseudo-ginseng root, rhizoma drynariae, himalayan teasel root, prepared frankincense, prepared myrrh, native copper, peach kernel, rheum officinale, eucommia bark, bletilla, crab, dragon's blood, ground beeltle, red paeony root, muskmelon seed, safflower, cutch, pangolin scales, cassia twig, szechuan lovage rhizome, medicinal cyathula root, earthworm, sappan wood, cortex albiziae, obscured homalomena rhizome, cibotiumbarometz, drgon's bones, gecko, nux vomica, common clubmoss herb, platycodon root, herb of oldham groundsel, papaya and cinnabar. The traditional Chinese medicine composition for treating bone fracture diseases belongs to a pure traditional Chinese medicinal preparation, is safe and reliable, has no toxic and side effect, has the characteristics of low price, high efficiency and quick effectiveness compared with medicaments of the same kind, and is mainly used for treating symptoms such as bone fracture, bone injury, bone crack, bone nonunion, comminuted fracture, old fracture and the like.

The invention relates to a preparation method of a pharmaceutical composition preparation treating apoplexy sequelae. The method includes volatile oil extraction and inclusion, ethanol extraction, water extraction, medicinal fine powder crushing, preparation molding and other steps. Compared with traditional preparations, the medication compliance of patients can be improved obviously. Under the premise of retaining original preparation efficacy, the pharmaceutical preparation prepared by the method provided in the invention can realize rapid absorption, effective components can intensively reach nidi to take fast effect, and the bioavailability is high. The pharmaceutical preparation prepared by the method disclosed in the invention has improved efficacy.

The invention provides pearl capsule with twenty-five components, a preparation method and a quality detection method thereof. The preparation method includes steps of dividing the twenty-five medicinal materials into four parts, namely mineral and precious medicine, precious and refine medicine, medicinal material containing volatile oil and medicinal material containing water-soluble components, crushing the mineral and precious medicine to 80 mesh, uniformly mixing; crushing the medicinal material containing high volatile oil to crude powder, extracting volatile oil, using beta-cyclodextrin for clathration; carrying out water extraction for the medicinal material containing water-soluble components, concentrating to relative density of 1.25-1.35 under reduction pressure, mixing the three parts, drying at 60-80 DEG C, crushing to 80 mesh; respectively grinding the precious and refine medicine, namely buffalo horn concentrated powder, cow-bezoar and musk into fine powder, mixing, adding beta-cyclodextrin and dextrin for mixing, and packaging into capsule. The high efficiency liquid chromatogram method is used for detecting content of piperine, and the thin layer chromatography method is used for discriminating nine objects.

The invention discloses a bone fracture setting ointment and method for preparing same. The bone fracture setting ointment is prepared by the following components: standard roots, Eupolyphaga, keel, crabs, wild grape root, Wu Chia Pee, alpine yallow herb, kusnezoff monkshood, Sichuan aconite root, strychnos nux-vomica, datura flower, pyrite, cassia twig, Asarum, monkshood, Eupatorium japonicum, borneol, gentiana macrophylla pall, notoginseng, buck grass, bark of eucommia, black bone, Drynaria, angelica, frankincense, myrrh, bletilla, aucklandia root, loranthus mulberry mistletoe, amber, elder, Vaseline, sesame oil, and wine. The method includes: placing the Vaseline into the wok, simmering, removing the fire and adding in benne oil and wine, and then adding the other components in the wok, stirring evenly and then spreading cool to form the bone fracture setting ointment. The invention can rapidly disperse the swelling and stop the pain, quicken the bone healing without any stimulation to the skin and any toxic side effects.

The invention relates to omega-3 phospholipid supplements for females, and in particular to omega-3 phospholipid supplements with increased bioavailability as evidenced by increased EPA and DHA in plasma phospholipids and an increase in omega-3 index as compared to males. In preferred embodiments, the omega-3 phospholipid is krill oil.

The present invention relates to a plaster for relief pain of viscera muscle joint, and a method for preparing the same. To resolve the problems of worse treating effect and side effect using existing medicine, the medicine provided by the invention is prepared from raw materials added plant oil and yellow lead of unsaturated fatty acid by weight rate as follows: 5-15 parts toad, 2-7 parts lbamboo knot cyperus rotundus l, 0.7-2.2 parts jiazhu, 3-10 parts paris, 5-15 parts crab, 2-7 parts seseli mairei wolff, 2-7 parts dragon arum, 2-7 parts herb of alpine yarrow, 2.5-7.5 parts raw radix aconiti kusnezoffii, 3-8 parts curcuma, 2.5-7.5 parts raw monkshood, 3-8 parts zedoary, 4-12 parts zushima, 2-5 parts olibanum, 2-5 parts myrrh, 2-7 parts qianjin vine, 2-7 parts nux vomica, 3-8 parts xugufeng, 4-9 parts angelica, 4-12 parts hawthorn, 2-7 parts raw pinellia ternate, 3-8 parts naoyanghua, 2-5 parts liquorice, 4-12 parts bamboo knot sanchi, 4-12 parts clematis root, 3-7 parts datura stramonium seed, 3-8 parts aconitum pendulum, 0.02-0.08 moschus. The plant oil is 50-150 parts tung oil and 30-90 parts black sesame oil. The weight rate of plant oil and yellow lead is 120-200 / 14-22. The medicine has wide application effect, and is suitable for treating pain of viscera muscle joint, long chronic illness. The medicine also has obvious cure effects without toxic side effect for treating acute or chronic gastritis, enteritis, diarrhea, dysmenorrhea, low back pain, neck and lumbar disc herniation, orthopaedics and traumatology. The medicine has effects of promoting circulation of qi and blood, clearing meridians and collaterals, using poisons as antidotes, dehydration detumescence, resolving the nodule, promoting blood circulation and removing blood stasis, dispelling wind chill and dampness syndromes, and can reach aim at both temporary solution and permanent control.

The invention relates to a traditional Chinese medicine powder for eliminating slough and promoting granulation and a preparation method thereof, frankincense, myrrh, catechu, borneol, musk, dragon's blood, sanchi, fossilized and crab spawn are taken as raw materials, the traditional Chinese medicine powder is characterized in that the contents (weight) of the raw materials are as follows: 5-15g of frankincense, 5-15g of myrrh, 5-15g of catechu, 5-15g of dragon's blood, 5-15g of sanchi, 1-6g of borneol, 0.1-1g of musk, 1-6g of fossilized and 5-12g of crab spawn, and the herbal medicines are well prepared according to the standards and ground to fine powder for standby. The invention has the advantages that, the cost of the raw materials is low, the traditional Chinese medicine powder can kill bacteria, remove suppuration and eliminate sore of various types of ulcerative skin stubborn diseases in a short period of time and simultaneously has the effects of eliminating slough and promoting granulation, thereby being applicable to all the skin ulcers and all the ulcerative running sores, malignant tumors, unhealed wounds and other symptoms, such as ulcers of upper and lower extremities, periostitis, unknown running sores, and the like; the effect is significant, the treatment course is short, the medical cost is low, and the economic burden of patients is reduced.

The invention discloses a Ruyizhenbao medicine composite, which is prepared by adopting the following steps of essential oil extraction and inclusion, ethanol extraction, water extraction, fluid extract drying, medicinal material fine powder crushing, expensive and fine medicine fine powder preparation and the like. Pharmaceutically conventional auxiliary materials are added according to a conventional process to be prepared into clinically acceptable dosage forms such as: powders, capsules, tablets, oral liquid, condensed pills, granular formulations, pills, pellets and slow release preparations. The invention is characterized in that the Ruyizhenbao composite is prepared by taking phytochemical components as the material base and the pharmacodynamics activity as the guidance by adoptinga modern extraction preparation method. The medicinal preparation prepared by the method disclosed by the method has the advantages of high absorption rate, stable pharmacodynamic components, high bioavailability and the like under the condition that the pesticide effects of the raw preparation are remained.

The present invention provides a strong coaptation medicine 'shuanglongjiegusan' for treating fracture, injuries from falls which belongs to plarmacy technology field. The shuanglongjiegusan is a hereditary secret formula of meng's coaptation. The medicine is prepared from Chinese traditional medicines by weight including 8-12 parts olibanum, 8-12 parts myrrh, 8-12 parts radix dipsaci, 3-8 parts ephedra, 8-12 parts tuchong, 18-22 parts dragon's blood, 8-12 parts melon seed, 8-12 parts angelic, 3-8 parts medicated leaven, 8-12 parts shenjiang, 8-12 parts crab shell, 5-10 parts fired pyrite, 17-22 parts deer's horn, 3-8 parts saffron, 0.1-0.3 parts muskiness, 2-5 parts vermilion, 3-8 parts borneol; The preparing technology is: weighing as formulation, then pulverizating into fine powder. The medicine treats mainly in: all large fractures, injuries from falls, all closed fracture, fracture delay connection, lumbago etc., and has advantages of positive curing effect, simply processing, non-toxic side effect, rapid stop-pain and coaptation.

A dietary supplement composition is formulated in a therapeutically effective amount to treat the eye of an individual. The composition includes a perilla seed oil extract, astaxanthin, and at least one carotenoid selected from the group consisting of lutein, trans-zeaxanthin and meso-zeaxanthin.