Pearl capsule with twenty-five components, preparation method and quality detection method thereof

A quality inspection method, pearl technology, applied in the direction of measuring devices, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of limited research in laboratories and less industrial production, so as to improve curative effect, increase stability, The effect of increasing compliance

Active Publication Date: 2009-09-16
NINGXIA DUOWEI PHARMA
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AI Technical Summary

Problems solved by technology

[0008] Inclusion technology is more and more widely used in traditional Chinese medicine preparations. Due to the limitations of β-cyclodextrin itself and the specific technical conditions required for inclusion technology, many studies are limited to laboratories, and industrial production is less

Method used

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  • Pearl capsule with twenty-five components, preparation method and quality detection method thereof

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Embodiment Construction

[0045] The present invention is described in detail below in conjunction with accompanying drawing with example,

[0046] Take the preparation of 1000 preparation units as an example:

[0047] Prescription: pearl 8.44g, nutmeg 16.89g, travertine 42.23g

[0048] Tsaoko 12.67g, Cloves 21.11g, Dalbergia 42.23g

[0049] Cardamom 16.89g Myrobalan 54.89g Sandalwood 33.78g

[0050] Amla 42.23g, Agarwood 33.78g, Cinnamon 16.89g

[0051] Myrobalan 42.23g, crab 21.11g, woody fragrance 33.78g

[0052] Mallow fruit 33.78g Piper longum 16.89g Strawberry seedling 42.23g

[0053] Golden stone 16.89g Concentrated powder of buffalo horn 25.34g Celery seed 16.89g.

[0054] Saffron 8.44g Nigella seeds 12.67g Bezoar 0.42g

[0055] Musk 0.42g

[0056] The twenty-five medicinal materials in the prescription are divided into four parts according to the category and chemical properties of each medicinal flavor, precious mineral drugs, precious an...

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Abstract

The invention provides pearl capsule with twenty-five components, a preparation method and a quality detection method thereof. The preparation method includes steps of dividing the twenty-five medicinal materials into four parts, namely mineral and precious medicine, precious and refine medicine, medicinal material containing volatile oil and medicinal material containing water-soluble components, crushing the mineral and precious medicine to 80 mesh, uniformly mixing; crushing the medicinal material containing high volatile oil to crude powder, extracting volatile oil, using beta-cyclodextrin for clathration; carrying out water extraction for the medicinal material containing water-soluble components, concentrating to relative density of 1.25-1.35 under reduction pressure, mixing the three parts, drying at 60-80 DEG C, crushing to 80 mesh; respectively grinding the precious and refine medicine, namely buffalo horn concentrated powder, cow-bezoar and musk into fine powder, mixing, adding beta-cyclodextrin and dextrin for mixing, and packaging into capsule. The high efficiency liquid chromatogram method is used for detecting content of piperine, and the thin layer chromatography method is used for discriminating nine objects.

Description

Technical field: [0001] The invention relates to the technical field of new traditional Chinese medicines, in particular to twenty-five flavor pearl capsules, a preparation method and a quality detection method thereof. Background technique: [0002] Cerebrovascular disease is an important disease mainly caused by cerebral arterial system lesions. Because of its acute onset and serious condition, it has been listed as a key topic in clinical research. The disease is called stroke in traditional Chinese medicine, and it often manifests as hemiplegia and aphasia. It is mainly caused by three aspects of vascular disease, blood pressure and blood changes, and the clinical manifestations are mostly cerebral thrombosis and cerebral hemorrhage. [0003] The formation of cerebral hemorrhage is due to the sclerosis and degeneration of the cerebrovascular wall, which makes the intima of the artery rough, the wall of the vessel is narrow, the blood flow is slow, and the formed compone...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P9/10G01N30/36G01N30/90A61K33/06A61K33/10A61K35/32A61K35/413A61K35/55A61K35/56A61K35/612
Inventor 王文超王景冷晓红王春红李晓萍
Owner NINGXIA DUOWEI PHARMA
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