8 results about "Carotenoid composition" patented technology

Provided herein are pharmaceutical compositions comprising carotenoids, including liposomes that encapsulate carotenoids including ionizable carotenoids such as trans-crocetin. The provided compositions have uses in treating diseases, disorders and conditions associated with, but not limited to, infection, endotoxemia, inflammation, sepsis, ischemia, hypoxia, shock, stroke, lung injury, wound healing, traumatic injury, reperfusion injury, cardiovascular disease, kidney disease, liver disease, inflammatory disease, metabolic disease, pulmonary disorders, blood related disorders and hyperproliferative diseases such as cancer. Methods of making, delivering, and using the pharmaceutical compositions are also provided.

Carotenoid compositions are described for management, treatment, and / or prevention of stress by reducing cortisol levels and / or improving distribution and / or density of macular pigment and thus improving overall health status. More particularly, a subject in need thereof for the method has disturbed macular pigment optical density or increased levels of cortisol as markers of psychological and physiological stress. Methods are also described of administering macular carotenoid compositions in daily doses of at least or about 0.005 mg / kg body weight of lutein, and at least or about 0.001 mg / kg body weight of meso-zeaxanthin and zeaxanthin isomer along with at least one food grade excipient and evaluating overall health status. The composition may be derived from plant extract containing xanthophylls and / or xanthophylls esters. The composition also reduces cortisol levels in the blood and relieves physiological stress, thus improving overall health status of a subject in need thereof.

The present invention provides a technique for synthesizing a carotenoid composition by a genetic recombination technique.　A transformant in which a first promoter, an upstream gene of a carotenoid biosynthesis gene including a crtY and crtZ operably linked to the first promoter, a second promoter having higher promoter intensity than the first promoter, and a ZEP gene and a CCS gene operably linked to the second promoter have been introduced into a host cell.

An encapsulated carotenoid composition is disclosed, wherein vegetable oils and fatty acids are mixed with a carotenoid with desired purity and at desired concentrations and emulsified with aqueous solution of maltodextrin, further adding specific ingredients such as ascorbic acid, Vitamin E acetate to arrive at a homogenous mixture, which is then spray died to obtain encapsulated fine powder of a carotenoid, wherein the said carotenoid ensures comparatively enhanced end- use formulation compatibility retaining the potency of the said carotenoids thereby imparting prolonged shelf life of such end-use formulations comprising the encapsulated carotenoids of the present invention. The carotenoid according to this invention may be lutein, or any other xanthophyll or a carotenoid and esters thereof and are water-dispersible.

A Capsicum annum extract composition (600) includes capsanthin in the range from 50% to 80%, zeaxanthin in the range from 5% to 15%, and cryptoxanthin in the range from 1% to 5%.

This invention discloses a method for preparing a pollen and carotenoid composition and its application. The composition is prepared using the following raw materials in parts by weight: 100-10000 parts bee pollen and 0.1-100 parts carotenoids. The carotenoid crystals are then processed into carotenoid microcapsule powder using food colloids or similar methods at 50-70°C. The bee pollen and carotenoid microcapsule powder can be directly mixed to prepare solid beverages, hard capsules, etc.; alternatively, bee pollen can be granulated by adding 5-10% povidone solution, then mixed with the microcapsule powder raw material and excipients, and prepared into tablets under 5-15 kN pressure. The product obtained by this invention exhibits significantly improved storage and delivery stability in the combined application of carotenoid and pollen raw materials, effectively improving and expanding the application scenarios and synergistic effects of the two functional raw materials. It is suitable for the industrial production and functional creation applications of these two related raw materials.

Provided herein are pharmaceutical compositions comprising carotenoids, including liposomes that encapsulate carotenoids including ionizable carotenoids such as trans-crocetin. The provided compositions have uses in treating diseases, disorders and conditions associated with, but not limited to, infection, endotoxemia, inflammation, sepsis, ischemia, hypoxia, shock, stroke, lung injury, wound healing, traumatic injury, reperfusion injury, cardiovascular disease, kidney disease, liver disease, inflammatory disease, metabolic disease, pulmonary disorders, blood related disorders and hyperproliferative diseases such as cancer. Methods of making, delivering, and using the pharmaceutical compositions are also provided.

A Capsicum annum extract composition (600) includes capsanthin in the range from 50% to 80%, zeaxanthin in the range from 5% to 15%, and cryptoxanthin the range from 1% to 5%.