Skin whitening toning lotion containing lipidosome and preparation method thereof

The technology of liposome and lotion is applied in the field of whitening lotion and its preparation, which can solve the problems that it is difficult to achieve the best effect of a whitening agent, the affinity penetrant is not good enough, and the whitening lotion has not yet been seen, and achieves outstanding whitening effect. , The effect of moisturizing and softening the skin, inhibiting the production of melanin

Inactive Publication Date: 2016-12-14
上海乐宝日化股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And there are many whitening agents that are unstable to light and heat, and are prone to discoloration or inactivation
Water-soluble skin-friendly penetrants are not good enough, and oil-soluble whitening agents are more compatible with the skin, but there are two methods for water-based formulations of oil-soluble ingredients: one is emulsification and the other is solubilization. It will increase the risk of irritation, and the emulsified water is difficult to stabilize
And the amount that the skin can really absorb is not much, it is difficult to achieve the best effect of whitening agent
[0003] At present, there are no related products or literature reports about whitening lotion containing liposomes

Method used

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  • Skin whitening toning lotion containing lipidosome and preparation method thereof
  • Skin whitening toning lotion containing lipidosome and preparation method thereof
  • Skin whitening toning lotion containing lipidosome and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Example 1 Whitening lotion containing liposomes

[0041] The formula (weight percentage) of the liposome-containing whitening lotion in this example is as follows:

[0042] Liposomes, including:

[0043]

[0044]

[0045] Other raw materials, including:

[0046]

[0047] The preparation process of the liposome-containing whitening lotion in this embodiment is as follows:

[0048] 1. Prefabricated liposomes: Disperse hydrogenated lecithin in glycerol and 1,3-butanediol and stir well. Add ascorbyl tetraisopalmitate and tocopherol acetate into the stirring, mix well, add an appropriate amount of water at 50°C, stir evenly, heat to about 75°C, homogenize at 3000rpm / min for 5 minutes, and measure the particle size. The particle size is about 100nm, ready for use;

[0049] 2. Mix water and EDTA-2Na, (PEMULEN TR-1), xanthan gum, stir and disperse evenly, heat to 85°C and continue stirring for 30 minutes;

[0050] 3. Cool to 45°C, add 1,3-propanediol, dipropylene glycol, PEG-8, nicotinam...

Embodiment 2

[0062] Example 2 Whitening lotion containing liposomes

[0063] The formula (weight percentage) of the liposome-containing whitening lotion in this example is as follows:

[0064] Liposomes, including:

[0065]

[0066] Other raw material components include:

[0067]

[0068] The preparation process of the liposome-containing whitening lotion in this example is the same as that in Example 1.

Embodiment 4

[0069] Example 4 Whitening lotion containing liposomes-whitening contrast test

[0070] Choose a liposome-free whitening lotion (the formula of the comparative example) and a liposome-containing whitening lotion (Example 1) for comparison, and select 10 volunteers for testing. After the same tester cleans the facial skin, Dry it and pat the lotion on the face skin with your hands. Use liposome-free whitening lotion on the left face and liposome-containing lotion on the right face for 2 weeks, using the skin melanin and hemoglobin test probe (Mexameter MX18) produced by COURAGE+KHAZAKA (CK) in Germany ) The melanin content of the tested area was measured respectively, and the results are shown in Table 1.

[0071] Table 1 Average melanin reduction results

[0072] Time

[0073] It can be seen from Table 1 that although liposome-free whitening lotion also has the effect of whitening skin, the whitening effect of liposome-containing whitening lotion is significantly better than tha...

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Abstract

The invention relates to the field of cosmetics and particularly discloses skin whitening toning lotion containing lipidosome and a preparation method thereof. The skin whitening toning lotion is prepared from, by weight, 0.1-10% of lipidosome, 0.01-5% of thickener, 1-30% of polyalcohol humectant, 0.1-5% of cosmetically-accepted carrier and the balance water. The sum of the weight percentages is 100%. The lipidosome ingredient is added to the toning lotion, the formula is reasonable, the dry environment can be effectively resisted, the elastic and smooth skin can be restored, the skin is moisturized and tender, production of melanin is effectively restrained, the skin is brighter and whiter, the skin whitening toning lotion can deeply penetrate into the bottom layer of the skin, the dry environment is effectively resisted, the elastic and smooth skin is restored, and the skin is moisturized and tender.

Description

Technical field [0001] The invention belongs to the field of cosmetics, and specifically relates to a whitening lotion containing liposomes and a preparation method thereof. Background technique [0002] There are water-soluble, oil-soluble and alcohol-soluble types of whitening agents. Basically, the whitening agent is directly added to the formula to dissolve or emulsify into the product. And there are many whitening agents that are unstable to light and heat, and are easy to change color or inactivate. Water-soluble whitening agents are not good enough for skin affinity, and oil-soluble whitening agents have good skin compatibility, but there are two ways to add oil-soluble ingredients in water formulations: one is emulsification, the other is solubilization and solubilization It will increase the risk of irritation, and the emulsion is difficult to stabilize. And the amount that the skin can really absorb is not much, it is difficult to achieve the best effect of the whiten...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/67A61K8/55A61K8/34A61K8/14A61Q19/02A61Q19/00
CPCA61K8/676A61K8/14A61K8/345A61K8/553A61K8/678A61Q19/00A61Q19/02
Inventor 黄萍王晓娟
Owner 上海乐宝日化股份有限公司
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