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Application of theabrownin to senescence resistance

A theabrownin, anti-aging technology, applied in the direction of application, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problem that the application of theabrownin has not been found, and it has not been involved in improving telomerase To achieve the effects of slowing down organ aging, maintaining skin elasticity, and removing skin elasticity and pigmentation

Inactive Publication Date: 2017-01-25
杭州茗褐生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, the application of theabrownin in the field of anti-aging has not been found, especially related technical solutions for improving the activity of telomerase

Method used

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  • Application of theabrownin to senescence resistance
  • Application of theabrownin to senescence resistance
  • Application of theabrownin to senescence resistance

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0040] The preparation method of theabrownin used in the present invention comprises the steps:

[0041] A. Cross-linking of glucose oxidase to nanoscale Fe 3 o 4 , spread on the bottom of the container, add CO 2 and inert material Al 2 o 3 Form the enzyme mixture, seal and set aside;

[0042] B. Crush the tea leaves, add water, heat to boiling, let stand and cool, then filter to form tea soup;

[0043] C. Mix the enzyme mixture with the tea soup for circulation heating-cooling;

[0044] D. After circulating heating-cooling for 12-48 hours, put the magnet into the container, absorb the supernatant and filter it;

[0045] E. Evaporating the filtrate to obtain crude tea pigment extract, then dissolving the crude tea pigment extract with an alcoholic aqueous solution, and then concentrating and drying the obtained solution to obtain highly active theabrownin.

[0046] The method that the present invention is used for testing telomerase activity is:

[0047] 1 Select the c...

Embodiment 1

[0053] sample discription:

[0054]

[0055] Telomerase Boost Percentage:

[0056]

[0057]

[0058] The above data shows that under the same quality, theabrownin prepared by the method of the present application is superior to resveratrol in terms of telomerase activity enhancement level.

Embodiment 2

[0060] sample discription

[0061]

[0062] Telomerase Boost Percentage:

[0063] concentration Theabrownin 0.3μg / mL 9.31％ 1.2μg / mL 18.01％ 4.8μg / mL 32.59％ 19.2μg / mL 67.21％

[0064] The above data shows that when theabrownin reaches the same enhanced level of telomerase activity, the sample quality required for the theabrownin prepared by the method of the present application is less than that of the theabrownin prepared by the general method.

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Abstract

The invention relates to application of theabrownin to senescence resistance, in particular to application of the theabrownin to improvement in activity of telomerase. When the concentration of the theabrownin is 0.15-30 microgram / mL, 5-75% of the activity of the telomerase can be improved. The application of the theabrownin to senescence resistance has the advantages that according to determination, the theabrownin is capable of improving the activity of the telomerase, can be prepared into food, drinks, drugs, quasi-drugs or cosmetics, and can be further prepared into an additive of the food, the drinks, the drugs, the quasi-drugs or the cosmetics.

Description

technical field [0001] The invention relates to the application of theabrownin in anti-aging, in particular to the use of theabrownin to improve the activity of telomerase. Background technique [0002] Theabrownin (TB) is a kind of brown pigment in tea which is soluble in water and insoluble in ethyl acetate and n-butanol, and is an important component of tea pigment in tea. The invention patent with the publication number CN103478336A previously applied by the applicant discloses "a highly active tea pigment and its extraction method and application". Through the technical scheme disclosed in this invention, the content percentage of theabrownin can be extracted to be 50% -90% tea pigments. In this patent application, tea pigments are collectively referred to as theabrownin dry powder. [0003] Theabrownin maintains the cardiovascular and cerebrovascular system and reduces the incidence of cardiovascular and cerebrovascular diseases by assisting in lowering blood fat and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/82A61K47/46A61P39/06A61K8/9789A61Q19/08A23L33/105A23L33/00A61Q19/02A61Q19/00A61Q17/04G01N21/33G01N27/447
CPCA61K36/82A23V2002/00A61K8/97A61K47/46A61K2236/331A61Q17/04A61Q19/00A61Q19/02A61Q19/08G01N21/33G01N27/447A23V2200/318A23V2200/302A23V2250/214
Inventor 张进
Owner 杭州茗褐生物科技有限公司
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