Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Streptococcus equi subsp and production technology for preparing hyaluronic acid through streptococcus equi subsp

A technology of Streptococcus equi and hyaluronic acid, applied in bacteria, microorganisms, microorganisms, etc., can solve the problems such as the inability to stimulate the activity of bacteria, the low yield of hyaluronic acid, and the long fermentation period. The effect of high output rate and lower production cost

Active Publication Date: 2017-02-22
东营佛思特生物工程有限公司
View PDF3 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, the process of producing hyaluronic acid by microbial fermentation has a long fermentation cycle, and the fermentation process cannot be carried out according to the characteristics of the strain, resulting in the inability to stimulate the activity of the strain, low yield of hyaluronic acid, and poor product quality

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment １

[0021] Streptococcus equi subsp. zooepidemicus ( Streptococcus equi subsp. zooepidemicus ) DCS005. At present, this Streptococcus equi subspecies zooepidemicus is preserved in the General Microbiology Center of the China Microbiological Culture Collection Management Committee. .12782, the Latin name for the strain is Streptococcus equi subsp. zooepidemicus , The reference microorganism (strain): DCS005, the date of preservation is July 14, 2016.

[0022] The production process for preparing hyaluronic acid with the described Streptococcus equi subspecies zooepidemicus comprises the following steps:

[0023] (1) Shake flask seed solution culture;

[0024] (2) Bacterial expansion and cultivation;

[0025] (3) Fermentation, first feed sterile oxygen-containing air to ferment, and then feed nitrogen to continue fermentation;

[0026] (4) Purification.

[0027] The culture solution in steps (1), (2), and (3) includes starch 1%, sucrose 0.5%, beef extract 0.5%, yeast powder 0.5...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a streptococcus equi subsp and a production technology for preparing hyaluronic acid through the streptococcus equi subsp. According to the novel screened streptococcus equi subsp, the improved fermentation technology is combined, the output rate of a hyaluronic acid product is high, and can be 9.5 g / L. The fermented streptococcus equi subsp is easy to separate and purify, and the production cycle is short; production is easy to control, the streptococcus equi subsp is suitable for industrial mass production, the yield is high, and the production cost is greatly reduced.

Description

technical field [0001] The invention relates to the technical field of hyaluronic acid production, in particular to a Streptococcus equi subsp. Background technique [0002] At present, the process of producing hyaluronic acid by microbial fermentation has a long fermentation period, and the fermentation process cannot be carried out according to the characteristics of the strain, resulting in the inability to stimulate the activity of the strain, resulting in low hyaluronic acid yield and poor product quality. It is a technical problem to be solved in the present invention to develop new strains for fermentation and to improve the production process according to the characteristics of the strains to increase the quality and output of hyaluronic acid. Contents of the invention [0003] The object of the present invention is to provide a streptococcus equi subspecies zooepidemicus and a production process for preparing hyaluronic acid in view of the above-mentioned defects....

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C12N1/20C12P19/26C12R1/46
CPCC12P19/26C12N1/205C12R2001/46
Inventor 张振武朱连明肖馗缨惠贤秋马骞寰牛玲晓
Owner 东营佛思特生物工程有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com