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Medicine composition for enhancing immunity of animals and method for preparing medicine composition

A composition and immunity technology, applied in the field of medicine, to achieve the effects of increased dissolution, improved bioavailability and increased specific surface area

Inactive Publication Date: 2017-03-08
CHENGDU QIANKUN VETERINARY PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there is no report on the combination of Paulownia leaves and Astragalus to improve the immune enhancement effect of Astragalus

Method used

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  • Medicine composition for enhancing immunity of animals and method for preparing medicine composition

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Comparison scheme
Effect test

Embodiment 1

[0026] The preparation of embodiment 1 medicine micropowder of the present invention

[0027] Take the medicinal materials, air-dry them so that the water content is less than 5%, and conventionally crush them through a No. 5 sieve (80 mesh) to obtain a fine powder mixture of the medicinal materials. Pulverize for more than 20 minutes to obtain superfine powder with a particle size of less than 50 μm.

Embodiment 2

[0028] The preparation of embodiment 2 pharmaceutical granules of the present invention

[0029] Take the medicinal materials, add 20 times the amount of water to decoct and extract twice, extract for 1 hour each time, filter the decoction, combine the filtrates, concentrate to an extract with a relative density of 1.15-1.20 (measured at 60°C), add ethanol to make the alcohol-containing The amount reaches 60%, stir, stand still for more than 24 hours, filter, the filtrate is concentrated to an extract with a relative density of 1.30-1.35 (measured at 60°C), add an appropriate amount of lactose, mix well, granulate, and dry at 60°C for 12 hours. Made into 1000g, that is.

Embodiment 3

[0030] Embodiment 3 The preparation of drug-soluble powder of the present invention

[0031] Take the medicinal material, add 20 times the amount of water to decoct and extract twice, extract for 1 hour each time, filter the decoction, combine the filtrates, concentrate to an extract with a relative density of 1.10-1.12 (measured at 60°C), spray-dry the extract and Collect the powder, add an appropriate amount of dextrin to 1000g, mix well, and obtain.

[0032] Prove the beneficial effects of the present invention below by drug effect experiment.

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Abstract

The invention discloses a medicine composition for enhancing the immunity of animals. The medicine composition is a preparation prepared from radix astragali and leaves of paulownia chinense. The medicine composition has the advantages that as shown by pharmacological experiments, the humoral immunity can be obviously enhanced if the leaves of the paulownia chinense and the radix astragali are jointly applied although obvious effects of enhancing the immunity cannot be realized by the leaves of the paulownia chinense, and the maintenance time of serum antibodies can be prolonged; pharmacological functions are superior to effects of the individually used radix astragali if the radix astragali and the leaves of the paulownia chinense are jointly used under the condition of identical administration dosage, and synergistic effects can be realized; the medicine composition has the optimal pharmacological functions when a mass proportion of the radix astragali to the leaves of the paulownia chinense is 333:667, and accordingly reference can be provided for clinical application of the preparation.

Description

technical field [0001] The invention relates to a pharmaceutical composition for enhancing animal immunity and a preparation method thereof, belonging to the field of medicine. Background technique [0002] Immunity is a protective physiological response for the body to recognize and eliminate its own substances. It has the functions of maintaining its own stability, preventing infection and immune surveillance. The level of immune function directly affects the body's disease resistance and production capacity. At present, the breeding industry is generally plagued by low animal immune function, especially immunosuppressive diseases such as pig blue ear disease, swine fever, and foot-and-mouth disease often lead to vaccine immunity failure, which not only wastes a lot of medical resources, but also increases the risk of disease transmission Sexuality makes animal diseases more and more complicated, and has caused serious impact and heavy losses on the healthy, rapid and stabl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/80A61K39/255A61P37/04A61P31/22
CPCA61K36/481A61K36/80A61K39/12A61K2236/331A61K2236/39A61K2236/51C12N2710/16334A61K2300/00
Inventor 吴学渊李军李超唐华侨李犹平
Owner CHENGDU QIANKUN VETERINARY PHARMA
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