Medicine composition for treating tuberculosis and preparation method thereof

A composition and technology of pulmonary tuberculosis, applied in the direction of drug combination, pharmaceutical formula, active ingredient of heterocyclic compounds, etc., can solve the problem of not obvious inhibition of dextran arthritis

Inactive Publication Date: 2017-03-22
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

It has also been reported that horse chestnut bark glucoside also has inhibitory effect on formaldehyde-induced arthri...

Method used

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  • Medicine composition for treating tuberculosis and preparation method thereof

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Effect test

Embodiment 1

[0040] Embodiment 1: the pharmaceutical composition for the treatment of pulmonary tuberculosis and preparation method thereof

[0041] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating pulmonary tuberculosis are: 5575g of walnut kernels, 1300g of lapis lazuli, 4735g of oysters, 2200g of nutmeg, 900g of fenugreek, 40g of lauric anhydride, 85g of (+)-scopolamine, and 65g of glycine;

[0042] Preparation:

[0043] (1) Take walnut kernels, lapis lazuli, oysters, nutmeg, cinnamon bark, lauric anhydride, (+)-scopolamine, glycine according to the ratio of raw materials, mix well, use ethanol with a concentration of 38% by weight as a solvent, and heat at 38°C Warm immersion extraction, the number of extractions is 8 times, each extraction time is 20 hours, and the amount of solvent used each time is 40 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, c...

Embodiment 2

[0046] Embodiment 2: the pharmaceutical composition for the treatment of pulmonary tuberculosis and preparation method thereof

[0047] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating pulmonary tuberculosis are: 5525g of walnut kernel, 1350g of kelp, 4685g of oyster, 2250g of nutmeg, 850g of fennel, 45g of lauric anhydride, 80g of (+)-scopolamine, and 70g of glycine;

[0048] Preparation:

[0049] (1) Take walnut kernels, lapis lazuli, oysters, nutmeg, cinnamon bark, lauric anhydride, (+)-scopolamine, glycine according to the ratio of raw materials, mix well, use ethanol with a concentration of 38% by weight as a solvent, and heat at 38°C Warm immersion extraction, the number of extractions is 8 times, each extraction time is 20 hours, and the amount of solvent used each time is 40 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates ...

Embodiment 3

[0052] Embodiment 3: the pharmaceutical composition for the treatment of pulmonary tuberculosis and preparation method thereof

[0053] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating pulmonary tuberculosis are: 5625g of walnut kernels, 1250g of lapis lazuli, 4785g of oysters, 2150g of nutmeg, 950g of fennel, 35g of lauric anhydride, 90g of (+)-scopolamine, and 60g of glycine;

[0054] Preparation:

[0055] (1) Take walnut kernels, lapis lazuli, oysters, nutmeg, cinnamon bark, lauric anhydride, (+)-scopolamine, glycine according to the ratio of raw materials, mix well, use ethanol with a concentration of 38% by weight as a solvent, and heat at 38°C Warm immersion extraction, the number of extractions is 8 times, each extraction time is 20 hours, and the amount of solvent used each time is 40 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, conc...

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Abstract

The invention discloses a medicine composition for treating tuberculosis and a preparation method thereof. The medicine composition is prepared from juglans regia, chlorite schist, oyster, nutmeg, cortex fraxini, lauric anhydride, (+)-scopolamine and glycine serving as raw medical materials in proportions, can be made into various dosage forms according to a conventional preparation technology and has an obvious curative effect on the treatment of the tuberculosis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a medicinal composition for treating pulmonary tuberculosis and a preparation method thereof. Background technique [0002] Tuberculosis is one of the common infectious diseases. In recent years, the incidence of pulmonary tuberculosis in my country has been increasing year by year, and the trend of rejuvenation is obvious... Clinically, the combined application of conventional bactericidal and bacteriostatic drugs against Mycobacterium tuberculosis has achieved relatively satisfactory therapeutic effects, but with the prolongation of medication time, the problem of drug resistance of Mycobacterium tuberculosis is becoming more and more serious. The development of the drug provides a reliable direction for the treatment of pulmonary tuberculosis, can significantly improve the therapeutic effect, is safe for use, and is worthy of clinical popularization and ...

Claims

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Application Information

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IPC IPC(8): A61K36/63A61K9/48A61K9/20A61P31/06A61P11/00A61K31/198A61K31/20A61K31/46A61K33/26A61K35/618
CPCA61K9/2031A61K9/2059A61K9/4866A61K31/198A61K31/20A61K31/46A61K33/26A61K35/618A61K36/185A61K36/52A61K36/63A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61K2300/00
Inventor 不公告发明人
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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