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Compound preparation capable of treating rheumatoid arthritis

A technology for compound preparations and arthritis, which is applied in the direction of anti-inflammatory agents, medical preparations containing active ingredients, pharmaceutical formulas, etc. It can solve problems that affect the quality of work and life, and achieve low cost, convenient administration, and high efficiency.

Inactive Publication Date: 2017-05-10
武汉名实生物医药科技有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most patients have recurrent illnesses, sometimes mild and sometimes severe, seriously affecting work and quality of life

Method used

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Examples

Experimental program
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Effect test

example 1

[0019] 1) 60g of Centella asiatica, 60g of guaiac wood, 60g of laurel, 60g of celery, 60g of white willow, 60g of cohosh racemosa, 60g of Zanthoxylum bungeanum, and 60g of millet pepper are mixed and then ultrafinely pulverized to obtain Chinese medicine powder;

[0020] 2) Mix the traditional Chinese medicine powder obtained in step 1) with 1 g of stevioside and 60 g of starch to prepare a mixed powder.

[0021] 3) Place the mixed powder obtained in step 2) in a wet mixing granulator, and add 40 g of sodium carboxymethyl cellulose under high-speed mixing to make a soft material; the speed is 188 rpm;

[0022] 4) Install the 16-mesh screen on the oscillating granulator, and make the soft material obtained in step 3) into wet granules;

[0023] 5) Pour the wet granules obtained in step 4) into a fluidized granulator in batches at a temperature of 75 to 80°C, and when the water content is less than 5% during random inspection, stop drying and discharge to obtain dry granules;

...

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Abstract

The invention relates to a compound preparation capable of treating rheumatoid arthritis. A preparation method comprises the following steps: carrying out superfine grinding on centella, lignum vitae, laurus nobilis, celery, white willow, black cohosh, Chinese prickly ash and capsicum frutescens to obtain traditional Chinese medicine powder; mixing the traditional Chinese medicine powder with stevioside and starch; putting the mixed powder into a wet type mixing granulator; in a high-speed mixed state, adding sodium carboxymethylcellulose to prepare a soft material; preparing the soft material into wet granules; pouring the wet granules into a boiling granulating machine in batches, and stopping drying when moisture is below 5%, so that dry granules are obtained; and sieving the dry granules, pouring into a three-dimensional mixing machine, adding magnesium stearate and mixing, pouring into a loading hopper of a high-speed tabletting machine to be tabletted, and carrying out sub-packaging, so that the compound preparation product is obtained. The compound preparation provided by the invention can dispel the wind and relieve pain, dispel cold and remove dampness, activate blood and remove stasis as well as tonify the liver and kidneys. Clinical observation tests verify that the compound preparation has the function of treating rheumatoid arthritis.

Description

technical field [0001] The invention relates to a compound preparation capable of treating rheumatoid arthritis. Background technique [0002] Rheumatoid arthritis is an inflammatory, progressive, symmetrical and destructive joint disease. Rheumatoid arthritis is one of the common diseases. It is a chronic and recurrent systemic disease mainly characterized by joint inflammation. In the early stage, there are migratory joint pain, swelling and dysfunction, and in the late stage, it is manifested as joint stiffness and deformity. loss, resulting in disability. Most patients suffer from repeated illnesses, sometimes mild and sometimes severe, seriously affecting work and quality of life. [0003] Traditional Chinese medicine believes that such diseases are mostly caused by exogenous wind, cold, and dampness, that is, the deficiency of righteousness is the root of the disease, the invasion of external evils is an important condition for the disease, and the deficiency of the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/81A61K9/16A61P19/02A61P29/00
CPCA61K36/81A61K9/1652A61K36/185A61K36/23A61K36/54A61K36/71A61K36/758A61K36/76A61K2300/00
Inventor 谈运良周捷刘浩
Owner 武汉名实生物医药科技有限责任公司
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