Five-kernel soft capsule and preparation method thereof
A technology of soft capsules and capsules is applied in the directions of capsule delivery, medical preparations containing active ingredients, medical raw materials derived from gymnosperm subphylum, etc. Effects of adverse reactions
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Embodiment 1
[0026] Example 1 Preparation of Wuren Soft Capsules
[0027] Take hemp seed 100g, Yu Liren 100g, Baiziren 50g, Trichosanthes kernel 100g and sweet almond 50g according to the formula, squeeze the five kernels respectively to obtain 65g of oil; the squeezed residue is steam distilled at 100°C for 120min to obtain volatile oil 15g, mixed for later use; the above oil was added into the auxiliary material polyethylene glycol 200 in a ratio of 1:1, mixed evenly, and machined to make soft capsules with glycerin gelatin as the capsule material; bottled, packaged, and passed the inspection to obtain Wuren soft capsules capsule.
Embodiment 2
[0028] Example 2 Preparation of Wuren Soft Capsules
[0029] Take hemp seed 100g, Yu Liren 100g, Baiziren 50g, Trichosanthes kernel 100g and sweet almond 50g according to the recipe, clean and press, put the oil separately, put the residue into a supercritical extraction kettle for extraction, the extraction pressure is 25MPa, extract The temperature is 50°C, the extraction time is 120min, CO 2 The flow rate is 18~20L · h -1 . The pressure of the separation tank I is controlled at 6 MPa and the temperature is 45°C; the pressure of the separation tank II is controlled at 5 MPa and the temperature is controlled at 35°C, and the oil can be obtained through separation, and the volatile oils of various raw materials are obtained, which are active ingredients and are used for later use; the above The oil is added with soybean oil and polyethylene glycol 300 as auxiliary materials in a ratio of 3:7, mixed evenly, and machined to make soft capsules with glycerin gelatin as the caps...
Embodiment 3
[0030] Example 3 Preparation of Wuren Soft Capsules
[0031] According to the formula, take 100g of hemp seed, 100g of Yu Liren, 50g of Baiziren, 100g of Trichosanthes kernel and 50g of sweet almond, clean them, dry them at 50°C for 10h, crush them to 0.42mm, and supercritical CO 2 Extraction, the extraction time is 5h, the extraction temperature is 45°C, and the extraction pressure is 30MPa, to obtain the volatile oils of various raw materials, which are the active ingredients, for use; add the above oils into the auxiliary materials polyethylene glycol 300 and Glycerin, mixed evenly, machine-made soft capsules with glycerin gelatin as the capsule material; pressed into aluminum-plastic foam boards, packaged, and passed the inspection to obtain Wuren soft capsules.
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